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Zometa - Femara Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women with Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy Clinical Trials Information presented on Clinical Trials Search isn't designed to be a substitute for certified healthcare advice, travels to or professional assistance using a genuine medical doctor. We are not physicians. Always confer with your dr. about Zometa - Femara Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women with Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy conditions. Clinical Trials Search.org is a site devoted to listing clinical research studies in human subjects. Zometa - Femara Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women with Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy Clinical research trials and Zometa - Femara Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women with Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy medical trials happen in hundreds of places across the United States. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials usually measure the effectualness of new drugs. The intention of the studies / undertakings is to solve certain human healthcare questions. Clinical trials are a popular manner for mDs, government agencies, and private sector companies to locate treatments for all forms of circumstances, such as Zometa - Femara Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women with Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy. Zometa - Femara Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women with Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy Clinical Trials and other clinical trials allow for volunteers to undergo medical treatment choices before they are available to the general public. Some times the human subjects get treatment for free of charge, and sometimes they are paid for their time. Occasionally there is a cost for a Zometa - Femara Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women with Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy clinical trial. Participants frequently get the best healthcare available for their Zometa - Femara Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women with Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy condition. Risks are a reality, nonetheless, and can include extra or frequent physician trips, medical risks (possibly life-jeopardising), and/or the treatment being ineffective. Trials are federally governed with exacting guidelines to protect clinical trials subjects.

Home > "Z" Clinical Trials Conditions > Zometa - Femara Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women with Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy

Zometa - Femara Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women with Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy



Zometa - Femara Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women with Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy

For Condition: Breast Neoplasms,Osteoporosis
Status: Completed
Sponsor(s): Novartis Pharmaceuticals ,
Synopsis: This protocol is designed to compare the effect on bone of Zometa 4 mg every 6 months when given upfront versus delayed start ( based on a post-baseline BMD T- Score below –2.0 SD at either the lumbar spine or total hip, or any clinical fracture unrelated to trauma, or an asymptomatic fracture discovered at the month 36 scheduled visit) in stage I-IIIa postmenopausal women with hormone receptor positive breast cancer who will receive Femara 2.5 mg daily as an adjuvant therapy.
Details:
Eligibility:
Study Type:
  Interventional, Prevention, Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/85 Years
Genders: Female
Protocol Entry Criteria: - Postmenopausal women with Stage I, II, or IIIa, ER and/or PR+ breast cancer with no clinical or radiological evidence of recurrent or metastatic disease before randomization. - Patients must have undergone complete tumor resection and margins of the resected specimen must be microscopically free of tumor. - In patients with tumor positive margins of the resected specimen, radiotherapy is mandatory.
Total Enrollment: 500

Location and Contact Information:

New Mexico Oncology Hematology, Ltd.
Albuquerque,  New Mexico,  87109
United States
 

Bay Area Oncology
Tampa,  Florida,  33607
United States
 

St. Joseph Regional Cancer Center
Bryan,  Texas,  77802
United States
 

Swedish Cancer Institute
Seattle,  Washington, 
United States
 

New England Hematology/Oncology Associates
Wellesley,  Massachusetts,  02481
United States
 

Oncology Partners Network
Cincinnati,  Ohio,  45238
United States
 

Northern Virginia Oncology Group
Fairfax,  Virginia,  22031
United States
 

Highlands Oncology Group
Springdale,  Arkansas,  72764
United States
 

The Sarah Cannon Cancer Center
Nashville,  Tennessee,  37203
United States
 

Methodist Cancer Center
Omaha,  Nebraska,  68114
United States
 

Pacific Shores Medical Group
Long Beach,  California,  90813
United States
 

Center for Oncology Research & Tx. PA
Dallas,  Texas,  75230
United States
 

Space Coast Medical
Titusville,  Florida,  32796
United States
 

VA Medical Center
San Juan,  ,  00927
Puerto Rico
 

Wilshire Oncology Medical Group
LaVerne,  California,  91750
United States
 

Cancer Research Network, Inc.
Plantation,  Florida,  33324
United States
 

Clinical Trials & Research Associates, Inc.
Montebello,  California,  90640
United States
 

Elmhurst Memorial Hospital
Elhurst,  Illinois, 
United States
 

Hematology-Oncology Associates of Northern NJ
Morristown,  New Jersey,  07962
United States
 

Odyssey Research Services
Bismark,  North Dakota,  58501
United States
 

Cancer and Blood Institute of the Desert
Rancho Mirage,  Colorado,  92270
United States
 

Charleston Hematology Oncology
Charleston,  South Carolina,  29403
United States
 

Nashat Y. Gabrail MD Inc.
Canton,  Ohio,  44718
United States
 

University of Pittsburgh Cancer Institute/Magee Womens Hospital
Pittsburgh,  Pennsylvania,  15213
United States
 

Rockwood Clinic, PS
Spokane,  Washington,  99220
United States
 

East Valley Hematology & Oncology
Burbank,  California,  91505
United States
 

Eastern Connecticut Hematology/Oncology Associates
Norwich,  Connecticut,  06360
United States
 

Kentuckiana Cancer Institute
Louisville,  Kentucky, 
United States
 

Virginia Physicians, Inc.- Oncology
Richmond,  Virginia,  23294
United States
 

Metro Minnesota CCOP
St. Louis Park,  Minnesota,  55416
United States
 

Pasco Pinellas Cancer Center
New Port Richey,  Florida,  34652
United States
 

Robert R. Carroll, MD, PA
Gainesville,  Florida,  32605
United States
 

Dayton Clinical Oncology Program
Dayton,  Ohio, 
United States
 

Louisiana Oncology Associates
Lafayette,  California,  70506
United States
 

Cancer Specialists of South Texas
Corpus Christi,  Texas,  78412
United States
 

Oncology Hematology Group of South Florida
Miami,  Florida,  33176
United States
 

Hemoncare PC
Brooklyn,  New York,  11235
United States
 

FL Community Cancer Center
Brooksville,  Florida,  34613
United States
 

Redwood Regional Medical Group
Santa Rosa,  California,  95403
United States
 

Cook Research Department at Spectrum Health
Grand Rapids,  Michigan,  49503
United States
 

Frederick Memorial Hospital Regional Cancer Therapy Center
Frederick,  Maryland,  21701
United States
 

Ocala Oncology Center
Ocala,  Florida,  33479
United States
 

Hematology-Oncology Centers of the Northern Rockies, PC
Billings,  Montana,  59101
United States
 

Physician Associates, Inc.
Cincinnati,  Ohio,  45238
United States
 


Additional Information:
Study ID Numbers:
  CZOL446E US32; 
Study Start Date: July 2002
Record last reviewed: March 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00050011

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2. Improving Bone Health in Adolescent Girls: The Youth Osteoporosis and Understanding Total Health (YOUTH) Study

3. Program to Prevent Osteoporosis in Girls

4. HORIZON-PFT: Pivotal Fracture Trial

5. The BONES Project: Building Healthy Bones in Children

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Zometa - Femara Adjuvant Synergy Trial (ZFAST) - Cancer Treatment Related Bone Loss in Postmenopausal Women with Estrogen Receptor Positive and/or Progesterone Receptor Positive Breast Cancer Receiving Adjuvant Hormonal Therapy

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