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Vitamin D Metabolism and the Williams Syndrome Clinical Trials Facts presented on Clinical Trials Search isn't designed to be a substitute for proven healthcare advice, calls or treatment using a real mD. We aren't mDs. Always confer with your physician on Vitamin D Metabolism and the Williams Syndrome conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Vitamin D Metabolism and the Williams Syndrome Clinical research trials and Vitamin D Metabolism and the Williams Syndrome healthcare trials happen in a lot of of localities across the United States of America. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally measure the potency of new drugs. The aim of the studies / undertakings is to answer particular human medical questions. Clinical trials are a popular manner for doctors, government agencies, and private sector corporations to discover remedies for all kinds of circumstances, such as Vitamin D Metabolism and the Williams Syndrome. Vitamin D Metabolism and the Williams Syndrome Clinical Trials and other clinical trials allow volunteers to get healthcare treatment alternatives before they are available to the general public. Most times the participants receive treatment for without cost, and occasionally they are paid for their time. Sometimes there is a cost for a Vitamin D Metabolism and the Williams Syndrome clinical trial. Human subjects often receive the most effective healthcare possible for their Vitamin D Metabolism and the Williams Syndrome condition. Risks are a reality, nonetheless, and may include more or frequent dr. calls, healthcare hazards (perhaps life-threatening), and/or the treatment being ineffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.

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Vitamin D Metabolism and the Williams Syndrome



Vitamin D Metabolism and the Williams Syndrome

For Condition: Williams Syndrome
Status: Completed
Sponsor(s): National Center for Research Resources (NCRR) ,
Synopsis: The Williams syndrome is a disease in which supravalvular aortic stenosis, an elfin facies, mental retardation and other congenital defects are sometimes associated with abnormal vitamin D and calcium metabolism. Whereas some patients have been reported to show increased sensitivity to vitamin D or an exaggerated response of serum 25-hydroxyvitamin D {25(OH)D} to administration of vitamin D and to have hypercalcemia caused by increased circulating 1,25-dihydroxyvitamin D{1,25(OH)2D} in infancy and early childhood, most patients have normal calcium metabolism and normal values for circulating 25(OH)D and 1,25(OH)2D. We propose to carry out further studies of vitamin D metabolism to elucidate the mechanism(s) for abnormal vitamin D metabolism. We will determine the response of serum 1,25(OH)2D to administration of 1,25(OH)2D3. Measurement of the 1,25(OH)2D in the patients compared to normal subjects will be the primary outcome.
Details:
Eligibility:
Study Type:
  Observational, Natural History, Case Control
Minimum Age/Maximum Age: 18 Years/50 Years
Genders: Both
Protocol Entry Criteria: Age 18 years to 50 years of age, patients and normal subjects
Total Enrollment: 

Location and Contact Information:

Medical University of South Carolina
Charleston,  South Carolina,  29425
United States
 


Additional Information:
Study ID Numbers:
  NCRR-M01RR01070-0562; 
Study Start Date: 
Record last reviewed: December 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00013962

Other Williams Syndrome Studies:
1. Study of Phenotype and Genotype Correlations in Patients With Contiguous Gene Deletion Syndromes

2. Vitamin D Metabolism and the Williams Syndrome

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