|
Visceral Adiposity and CVD Risk in Women Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for certified health advice, travels to or treatment by using a genuine physician. We are not physicians. Always consult your dr. on Visceral Adiposity and CVD Risk in Women conditions. Clinical Trials Search.org is a site committed to listing clinical research studies in human subjects. Visceral Adiposity and CVD Risk in Women Clinical research trials and Visceral Adiposity and CVD Risk in Women health trials occur in hundreds of cities throughout the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectivity of new drugs. The propose of the studies / undertakings is to resolve certain human health questions. Clinical trials are a popular means for physicians, government agencies, and private sector companies to locate treatments for all sorts of conditions, including Visceral Adiposity and CVD Risk in Women. Visceral Adiposity and CVD Risk in Women Clinical Trials and other clinical trials permit volunteers to acquire medical treatment choices before they are available to the masses. Some times the test subjects obtain professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a Visceral Adiposity and CVD Risk in Women clinical trial. Participants oftentimes recieve the most expert healthcare available for their Visceral Adiposity and CVD Risk in Women condition. Hazards are a reality, however, and can include extra or frequent physician visits, health risks (potentially life-endangering), and/or the treatment being uneffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.
|
|
|
|
|
|
|
Home > "V" Clinical Trials Conditions > Visceral Adiposity and CVD Risk in Women  Visceral Adiposity and CVD Risk in Women
Visceral Adiposity and CVD Risk in Women
For Condition: Heart Diseases,Obesity,Cardiovascular Diseases,Diabetes Mellitus
Status: No longer recruiting
Sponsor(s): National Heart, Lung, and Blood Institute (NHLBI) ,
Synopsis: To investigate the influence of total body fat and visceral fat on risk factors of diabetes and cardiovascular disease (CVD) in black and white women.
Details: BACKGROUND: Obesity is associated with increased morbidity and mortality. Concern about obesity has increased as the prevalence and severity have increased and the age of onset has decreased. It has also become clear that the location of fat may play an important role in determining the risk associated with obesity. Intra-abdominal fat has been shown to have particularly adverse consequences related to cardiovascular risk factors. Of interest is the fact that a number of studies have shown that the impact of overall adiposity differs by race. For each unit increase in adiposity, blacks appear to have less of an increase in blood pressure and triglycerides and less of a decrease in HDL cholesterol compared to whites. This racial difference in the relationship of adiposity to cardiovascular risk status may be related to differences in the distribution of fat. It is hypothesized that for a given level and increase in total body fat (measured by DEXA) black women will have less intra-abdominal fat (measured by magnetic resonance imaging). The cohort to be studied is a defined group of black and white women who were initially recruited into the study as children at age nine or 10 years as part of the National Heart, Lung and Blood Institute National Growth and Health Study. The cohort has been maintained and studied continuously over the past 11 to 12 years with about 75 percent of the original cohort remaining. DESIGN NARRATIVE: Subjects will be studied at age 23 and again at age 25 years. At each examination, subjects will have measurement of total fat (DEXA), intra-abdominal fat (MRI), fasting lipids and lipoproteins, insulin and glucose, blood pressure, and left ventricular mass (by echocardiography). In addition, the timing of pubertal maturation and dietary intake of fat and sucrose will be evaluated as potential determinants of intra-abdominal fat using data previously collected from age nine years to age 22 years. Study of this cohort provides a unique opportunity to evaluate whether differences in deposition of intraabdominal fat are related to racial differences in the relationship between adiposity and cardiovascular risk factors. It will also allow evaluation of childhood and adolescent determinants of adult intra-abdominal adiposity. The results of this investigation may provide insight into the prevention of intra-abdominal fat accumulation and ultimate lowering of risk for cardiovascular disease.
Eligibility:
Study Type: Observational, Natural History, Longitudinal, Defined Population
Minimum Age/Maximum Age: 23 Years/25 Years
Genders: Female
Protocol Entry Criteria: No eligibility criteria
Total Enrollment:
Location and Contact Information:
Overall Study Official:
StephenDaniels, , Children's Hospital Medical Center
Additional Information:
Study ID Numbers: 972;
Study Start Date: March 2001
Record last reviewed: April 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00021879
Other Heart Diseases Studies:
1. Pediatric Cardiomyopathy Registry
2. Central Obesity and Disease Risk in Japanese Americans
3. Measuring Sensitivity to Nonignorability
4. Heritage Study--Genetics, Exercise and Risk Factors
5. Inflammation Markers Over Time in Cardiovascular Disease
Related Studies:
Other Heart Diseases Clinical Trials
Other Clinical Trials
Other Clinical Trials
Visceral Adiposity and CVD Risk in Women
|
|
|
|
|
|
|
|
