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Trial for First-Line Treatment of Colorectal Cancer Clinical Trials Resources presented on Clinical Trials Search is not meant to be a substitute for proven health advice, calls or treatment with a real medical. We aren't mDs. Always consult your doctor on Trial for First-Line Treatment of Colorectal Cancer conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Trial for First-Line Treatment of Colorectal Cancer Clinical research trials and Trial for First-Line Treatment of Colorectal Cancer healthcare trials take place in a lot of of localities throughout the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectiveness of new does drugs. The function of the studies / projects is to figure out specific human medical questions. Clinical trials are a popular means for doctors, government agencies, and private sector corporations to find cures for all varieties of conditions, like Trial for First-Line Treatment of Colorectal Cancer. Trial for First-Line Treatment of Colorectal Cancer Clinical Trials and other clinical trials allow volunteers to access health treatment options before they are available to the masses. Many times the subjects receive professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a Trial for First-Line Treatment of Colorectal Cancer clinical trial. Human subjects often obtain the finest healthcare possible for their Trial for First-Line Treatment of Colorectal Cancer condition. Hazards are a reality, nevertheless, and might include additional or frequent dr. calls, health hazards (potentially life-jeopardizing), and/or the treatment being uneffective. Trials are federally regulated with stern guidelines to protect clinical trials patients.
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Home > "T" Clinical Trials Conditions > Trial for First-Line Treatment of Colorectal Cancer Trial for First-Line Treatment of Colorectal Cancer
Trial for First-Line Treatment of Colorectal Cancer
For Condition: Colorectal Cancer
Status: Recruiting
Sponsor(s): Eli Lilly and Company ,
Synopsis: In this study, patients will receive either ALIMTA (pemetrexed) plus irinotecan or 5-fluorouracil (5-FU), leucovorin, and irinotecan. The purposes of this study are to determine: - How ALIMTA plus irinotecan compares with 5-FU, leucovorin, and irinotecan in terms of efficacy. - The safety of ALIMTA plus irinotecan and any side effects that might be associated with it as compared with 5-FU, leucovorin, and irinotecan. - Whether ALIMTA can help patients with colorectal cancer.
Details:
Eligibility:
Study Type: Interventional, Treatment, Randomized
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: The patient must have: - Histologic or cytologic diagnosis of adenocarcinoma of the colon or rectum. - Performance status of 0 to 2 on the ECOG Performance Status Scale. - Standard postoperative adjuvant radiation therapy for rectal cancer is allowed. - Locally advanced or metastatic disease. - Must be 18 years of age. Exclusion Criteria: The patient must not have: - Received prior chemotherapy for advanced disease. Prior adjuvant therapy, including 5-FU, is allowed if it has been more than 12 months since the last treatment. - Received prior treatment with irinotecan in the adjuvant setting. - Are unable to take vitamin B12 or folic acid. - Are unable to interrupt aspirin, other nonsteroidal anti-inflammatory drugs, or COX-2 inhibitors for a 5-day period. - Have a second primary malignancy except carcinoma in situ of the cervix or nonmelanomatous skin cancer, unless that prior malignancy was diagnosed and definitively treated at least 5 years previously with no subsequent evidence of recurrence.
Total Enrollment:
Location and Contact Information:
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Hornsby, New South Wales,
Australia
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Wodonga, Victoria,
Australia
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Amsterdam, ,
Netherlands
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Krete, ,
Greece
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Geelong, Victoria,
Australia
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Trier, Rheinland-Pfalz,
Germany
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Douglas, Queensland,
Australia
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Magdeburg, ,
Germany
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Heraklion, Krete,
Greece
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
St Petersburg, Moscow,
Russian Federation
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Redcliffe, Queensland,
Australia
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Perth, Western Australia,
Australia
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Moscow, ,
Russian Federation
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Munchen, ,
Germany
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Madrid, ,
Spain
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Bedford Park, South Australia,
Australia
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Elche, Alicante,
Spain
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Halle, Munchen,
Germany
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Bankstown, New South Wales,
Australia
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
HOMBURG / SAAR, ,
Germany
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Sevilla, Barcelona,
Spain
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Amsterdam, ,
Netherlands
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Badalona, Barcelona,
Spain
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Kingswood Penrith, New South Wales,
Australia
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Halle, ,
Germany
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
NSW, QLD, South Australia, Victoria,
Australia
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Bielefeld, Nordrhein-Westfalen,
Germany
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
St Petersburg, ,
Russian Federation
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Woodville, South Australia,
Australia
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Hamburg, ,
Germany
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Tamworth, New South Wales,
Australia
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Berlin, ,
Germany
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Frankfurt/Main, ,
Germany
Recruiting
For additional information regarding investigative sites for this trial, contact the Clinical Trials Support Center at 1-877-CTLILLY (1-877-285-4559) or speak with your personal physician. *Recruiting*
Sevilla, ,
Spain
Recruiting
Additional Information:
Study ID Numbers: 2929;
Study Start Date:
Record last reviewed: April 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00079872
Other Colorectal Cancer Studies:
1. A Trial of ALIMTA (pemetrexed) Plus Irinotecan in Patients Who Have Been Previously Treated For Metastatic Colorectal Cancer.
2. Endoscopic Placement of Metal Stents in Treating Patients With Cancer- Related Duodenal Obstruction
3. Oxaliplatin Plus Irinotecan in Treating Patients With Metastatic Gastrointestinal Cancer
4. The identification of prognostic factors of late stage disease, particularly those that are modifiable, that might explain the worsened prognosis with colorectal cancer among veterans.
5. A Phase I Study To Test The Safety Of DAVANAT With and Without 5-Fluorouracil In Patients With Solid Tumors
Related Studies:
Other Colorectal Cancer Clinical Trials
Other South Australia Clinical Trials
Other Bedford Park Clinical Trials
Trial for First-Line Treatment of Colorectal Cancer
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