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Treatment of Erectile Dysfunction (ED) in Patients Treated for Prostate Cancer



Treatment of Erectile Dysfunction (ED) in Patients Treated for Prostate Cancer

For Condition: Prostate Cancer
Status: Recruiting
Sponsor(s): National Institute of Nursing Research (NINR) ,
Synopsis: The purpose of this study is to see if there is a significant difference in erectile function between men treated with sildenafil (FDA approved drug for treatment of erectile dysfunction) versus placebo after radiation therapy (RT) plus neoadjuvant total androgen suppression (TAS) for prostate cancer and to determine if there is a significant difference in overall sexual function and satisfaction between men treated with sildenafil versus placebo.
Details: This is a Phase III study. The study targets men with stage II and III prostate cancer recruited from the Radiation Therapy Oncology Group clinical trial (RTOG 99-10) treated with either 8 or 28 weeks of neoadjuvant TAS and RT with concurrent (8 week duration) TAS.
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Double-Blind, Placebo Control, Crossover Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 25 Years/65 Years
Genders: Male
Protocol Entry Criteria: - Men with prostate cancer in stages II-III.
Total Enrollment: 332

Location and Contact Information:

American College of Radiology *Recruiting*
Philadelphia,  Pennsylvania,  19107
United States
Recruiting Deborah  Bruner 215-728-2967


Additional Information:
Study ID Numbers:
  1-R01-NR007971-01; 
Study Start Date: September 2001
Record last reviewed: January 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00075127

Other Prostate Cancer Studies:
1. Perifosine to Treat Prostate Cancer

2. Vitamin E, Selenium, and Soy Protein in Preventing Cancer in Patients With High-Grade Prostate Neoplasia

3. A Phase III, Randomized Study of Atrasentan in Men with Metastatic, Hormone-Refractory Prostate Cancer

4. Thalidomide for the Treatment of Hormone-Dependent Prostate Cancer

5. Preoperative Thalidomide Followed By Radical Retropubic Prostatectomy In Select Patients With Locally Advanced Prostate Cancer

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Treatment of Erectile Dysfunction (ED) in Patients Treated for Prostate Cancer

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