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Tissue Acquisition for Molecular Diagnostics



Tissue Acquisition for Molecular Diagnostics

For Condition: Neoplasm
Status: Completed
Sponsor(s): National Cancer Institute (NCI) ,
Synopsis: Acquisition of fresh tumor and normal tissue samples are necessary for the preparation of cDNA libraries, microarray chips, and tissue specific probes, and proteomics development and validation. This protocol will allow acquisition of samples at the time of tissue sampling for surgery, diagnostic tests, or therapeutic phereses. These samples will be forwarded without patient identifiers, pathology reports, or other labels. Tissue pathology will be verified within the Laboratory of Pathology and samples used strictly for CGAP and Proteomic Initiative indications.
Details: Acquisition of fresh tumor and normal tissue samples is necessary for the preparation of cDNA libraries, microarray chips, tissue specific probes, and proteomics development and validation. This protocol will allow acquisition of patient samples at the time of tissue sampling for surgery, diagnostic tests, or therapeutic phereses. These samples will be forwarded without patient identifiers, pathology reports, or other labels. Tissue pathology will be verified within the Laboratory of Pathology and samples used strictly for CGAP and Proteomic Initiative indications.
Eligibility:
Study Type:
  Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: INCLUSION CRITERIA: All patients willing to sign the informed consent for whom tissue, blood or body fluids will be available are eligible. Histopathologic diagnosis will be confirmed in the Laboratory of Pathology, National Cancer Institute and is not a criteria for inclusion.
Total Enrollment: 50

Location and Contact Information:

National Cancer Institute (NCI)
Bethesda,  Maryland,  20892
United States
 


Additional Information:
Study ID Numbers:
  970138;  97-C-0138
Study Start Date: June 13, 1997
Record last reviewed: March 28, 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001580

Other Neoplasm Studies:
1. Phase I/II Study of Tac-Expressing Malignancies [Other than Adult T-Cell Leukemia (ATL)] with Yttrium-90 Radiolabeled Humanized Anti-Tac and Calcium-DTPA

2. Vaccine Therapy and Detection of Immunologic Responses with Tumor Specific Mutated RAS Peptides in Adult Cancer Patients with Solid Tumors

3. A Phase I Trial of Oral Perifosine with Different Loading Schedules in Patients with Refractory Neoplasms

4. Treatment of Patients with Cancer with Genetically Modified Salmonella Typhimurium Bacteria

5. A Pilot Study of Oxaliplatin in Combination with Capecitabine in Adult Cancer Patients

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