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Home > "T" Clinical Trials Conditions > Therapy for Reading Problems in Adults After Brain Injury Therapy for Reading Problems in Adults After Brain Injury
Therapy for Reading Problems in Adults After Brain Injury
For Condition: Dyslexia, Acquired,Cerebrovascular Accident,Brain Injuries
Status: Recruiting
Sponsor(s): National Institute of Child Health and Human Development (NICHD) ,
Synopsis: Adults who sustain brain damage due to stroke, head injury, or traumatic surgery may develop difficulty reading. This study examines the effectiveness of behavior-based programs to improve reading ability in these individuals.
Details: Acquired disorders of reading (acquired dyslexia) are common in patients with aphasia subsequent to left hemisphere stroke. Even when language functions recover sufficiently to enable the patient to return to work, continuing dyslexia often interferes significantly with job performance. This study will evaluate cognitive therapies for the treatment of acquired dyslexia. Each therapy is based upon a cognitive neuropsychological model of reading; the therapies target specific types of reading deficit and stem from the question of re-learning versus re-organization of function. The therapies focus on dyslexic disorders stemming from the following underlying deficits: 1) impaired access to the orthographic word form from the visual modality (pure alexia); 2) impaired orthographic/phonologic connections (phonologic/deep dyslexia); and 3) decreased ability to hold phonologic codes in memory (phonologic text alexia). Participants in this study will undergo a comprehensive and detailed battery of reading and reading-related tests to determine the underlying impairment causing the reading deficit. Based upon the results of these tests, the patient's dyslexic disorder will be characterized and, if appropriate, the patient will be assigned to one of the treatment programs devised specifically for that type of deficit. Treatment programs are evaluated for efficacy by comparing the accuracy and speed of reading pre- and post-treatment.
Eligibility:
Study Type: Interventional, Treatment, Non-Randomized, Open Label, Active Control, Parallel Assignment, Efficacy Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria - Reading deficit subsequent to stroke, traumatic brain injury, brain surgery, or other brain damage Exclusion Criteria - History of developmental dyslexia or learning disabilities - Best corrected vision less than 20/40 - Less than 10 years of formal education - Significant memory or comprehension problems
Total Enrollment: 58
Location and Contact Information:
Overall Study Official:
RhondaFriedman, Principal Investigator, Georgetown University Medical School
Georgetown University Medical Center *Recruiting*
Washington D.C., District of Columbia, 20057
United States
Recruiting
Additional Information:
Study ID Numbers: R01HD36019;
Study Start Date: October 1994
Record last reviewed: September 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00064805
Other Cerebrovascular Accident Studies:
1. Therapy for Reading Problems in Adults After Brain Injury
Related Studies:
Other Cerebrovascular Accident Clinical Trials
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Therapy for Reading Problems in Adults After Brain Injury
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