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The effect of LY333531 on protein in the urine in patients with type 2 diabetes.



The effect of LY333531 on protein in the urine in patients with type 2 diabetes.

For Condition: Diabetic Nephropathy
Status: No longer recruiting
Sponsor(s): Eli Lilly and Company ,
Synopsis: The purpose of this study are to determine 1) Whether Ly333531 can reduce uriniary albumin/creatinine excretion in patients with Type II diabetes and persistent albuminuria 2) Whether LY333531 reduces urinary TGF-B, 3) the safety of LY333531 and any side effects that may be associated with it.
Details:
Eligibility:
Study Type:
  Interventional, Treatment
Minimum Age/Maximum Age: 30 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Type 2 diabetes mellitus - Greater than or equal to 30 years of age - Albumin to Creatinine ratio (greater than 200 mg/g and less than 2000 mg/g) 4)Without language barrier. Exclusion Criteria: - Serum Creatinine greater than 2.0 mg/dl males or greater than 1.7 mg/dl females - B/P greater than 150 systolic and greater than 90 diastolic - Hemoglobin Alc greater than 11% - Liver Function Tests 2 times upper limit of normal - Poor medical or psychiatric risk.
Total Enrollment: 

Location and Contact Information:


Additional Information:
Study ID Numbers:
  6249; 
Study Start Date: 
Record last reviewed: July 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00044148

Other Diabetic Nephropathy Studies:
1. Soy Protein in Early Diabetic Nephropathy

2. Pirfenidone: A New Drug to Treat Kidney Disease in Patients with Diabetes

3. Treatment of Diabetic Nephropathy

4. Matrix metalloproteinases and Diabetic Nephropathy

5. Study of Drugs for High Blood Pressure and High Cholesterol in American Indians with Type 2 Diabetes at High Risk of Kidney or Heart Disease

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