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The Connection Between Areas in the Brain of Blind Patients



The Connection Between Areas in the Brain of Blind Patients

For Condition: Blindness,Brain Mapping,Healthy
Status: Completed
Sponsor(s): National Institute of Neurological Disorders and Stroke (NINDS) ,
Synopsis: The purpose of this study is to test the belief that specific areas of the brain are connected differently in blind patients than patients with sight. In addition, the study will examine the different anatomical connections between brain areas of patients who became blind early in life versus patients who became blind later.
Details: The purpose of this protocol is to test the hypothesis that the anatomical connectivity of occipital and somatosensory areas in early blind subjects differs from that in subjects who became blind later in life and from that in sighted volunteers.
Eligibility:
Study Type:
  Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: INCLUSION CRITERIA: Subjects with late blindness. Subjects with early blindness. Sighted volunteers. Age between 18 and 65 years. EXCLUSION CRITERIA: Subjects with personal or family history of seizures or other neurological or demyelinating disorders. Pregnant women tested after urine pregnancy test. Subjects with metal in the cranium except mouth. Subjects with intracardiac lines and implanted medication pumps. Subjects with increased intracranial pressure as evaluated by clinical means. Subjects with cardiac pacemakers. Intake or neuroleptics. Subjects with blindness secondary to degenerative CNS diseases.
Total Enrollment: 45

Location and Contact Information:

National Institute of Neurological Disorders and Stroke (NINDS)
Bethesda,  Maryland,  20892
United States
 


Additional Information:
Study ID Numbers:
  990031;  99-N-0031
Study Start Date: April 8, 1999
Record last reviewed: November 12, 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001926

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