Search Clinical Trials
By Condition
By Location (USA)
By Location (Other)
By Sponsor
Resources
Privacy Policy
About Us
Disclaimer
Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter Clinical Trials Information presented on Clinical Trials Search isn't intended to be a substitute for proven healthcare advice, trips or treatment using a real physician. We are not docs. Always confer with your mD on Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter conditions. Clinical Trials Search.org is a site dedicated to listing clinical research studies in human subjects. Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter Clinical research trials and Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter medical trials take place in hundreds of localities across the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials usually measure the effectiveness of new drugs. The intention of the studies / projects is to resolve certain human health questions. Clinical trials are a popular means for physicians, government agencies, and private sector corporations to detect remedies for all forms of circumstances, like Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter. Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter Clinical Trials and other clinical trials allow for volunteers to undergo healthcare treatment options before they are available to the masses. Most times the participants receive treatment for free, and every now and again they are paid for their time. Occasionally there is a cost for a Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter clinical trial. Subjects typically recieve the finest healthcare available for their Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter condition. Hazards are a reality, nonetheless, and might include more or frequent mD trips, health risks (potentially life-endangering), and/or the treatment being ineffective. Trials are federally regulated with stern guidelines to protect clinical trials subjects.

Home > "T" Clinical Trials Conditions > Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter

Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter



Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter

For Condition: Infection
Status: Recruiting
Sponsor(s): United Kingdom Children's Cancer Study Group ,
Synopsis: RATIONALE: Giving the antibioticteicoplanin by infusion and allowing bacteria to be exposed to the antibiotic for a longer period of time may be effective in preventing or controlling septicemia. PURPOSE: Randomized clinical trial to compare two different methods of giving teicoplanin in treating septicemia in patients who are receiving chemotherapy through a central venous catheter.
Details: OBJECTIVES: - Compare the response and cure rate of coagulase-negative staphylococcal septicemia in patients receiving chemotherapy through a central venous catheter treated with 2 different schedules of teicoplanin. OUTLINE: This is a randomized, multicenter study. Patients are stratified according to participating center and number of central venous catheter lumens (1 vs 2). Patients are randomized to one of two treatment arms. - Arm I: Patients receive teicoplanin IV bolus every 12 hours for 3 doses and then once daily for 5 doses (total of 7 days). - Arm II: Patients receive teicoplanin IV over 2 hours and/or by antibiotic lock every 12 hours for 3 doses and then once daily for 5 doses (total of 7 days). PROJECTED ACCRUAL: Approximately 490-1,360 patients will be accrued for this study within 2.2-6.2 years.
Eligibility:
Study Type:
  Interventional, Treatment
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: DISEASE CHARACTERISTICS: - Suspected septicemia caused by coagulase-negative staphylococci - Single or double lumen (no triple lumen) central venous catheter (CVC) (including subcutaneous ports) that can be flushed and aspirated - Expected to remain in situ for at least 8 weeks - No coagulase-negative septicemia associated with existing CVC within the past 12 weeks - Receiving chemotherapy for neoplastic condition, aplastic anemia, Fanconi's anemia, Langerhans' cell histiocytosis, or myelodysplasia PATIENT CHARACTERISTICS: Age: - 2 months and over Performance status: - Not specified Life expectancy: - Not specified Hematopoietic: - Not specified Hepatic: - Not specified Renal: - Creatinine clearance at least 60 mL/min PRIOR CONCURRENT THERAPY: Biologic therapy - Not specified Chemotherapy - See Disease Characteristics Endocrine therapy - Not specified Radiotherapy - Not specified Surgery - Not specified
Total Enrollment: 

Location and Contact Information:

Overall Study Official:
BarryPizer,  Study Chair,  Royal Liverpool Children's Hospital, Alder Hey

Addenbrooke's NHS Trust *Recruiting*
Cambridge,  England,  CB2 2QQ
United Kingdom
Recruiting Denise  Williams 44-1223-216-878

Birmingham Children's Hospital *Recruiting*
Birmingham,  England,  B4 6NH
United Kingdom
Recruiting Bruce  Morland 44-121-333-8233

Bristol Royal Hospital for Children *Recruiting*
Bristol,  England,  BS2 8BJ
United Kingdom
Recruiting Annabel  Foot 44-117-921-5411

Royal Liverpool Children's Hospital, Alder Hey *Recruiting*
Liverpool,  England,  L12 2AP
United Kingdom
Recruiting Heather  McDowell 44-151-228-4811

Southampton General Hospital *Recruiting*
Southampton,  England,  SO16 6YD
United Kingdom
Recruiting Janice  Kohler 170-379-6942

Queen's Medical Centre *Recruiting*
Nottingham,  England,  NG7 2UH
United Kingdom
Recruiting David  Walker 44-115-924-9924

Royal Marsden Hospital - Sutton *Recruiting*
Sutton,  England,  SM2 5PT
United Kingdom
Recruiting Kathy  Pritchard-Jones 44-20-8661-3496

Royal Hospital for Sick Children *Recruiting*
Edinburgh,  Scotland, 
United Kingdom
Recruiting Hamish  Wallace 0131-536-0426

Meyerstein Institute of Oncology at Middlesex Hospital *Recruiting*
London,  England,  WIT 3AA
United Kingdom
Recruiting Maria  Michelagnoli 44-20-7380-9950

Great Ormond Street Hospital for Children NHS Trust *Recruiting*
London,  England,  WC1N 3JH
United Kingdom
Recruiting Penelope  Brock 44-20-829-8832

Royal Hospital for Sick Children *Recruiting*
Glasgow,  Scotland,  G3 8SJ
United Kingdom
Recruiting E.M.  Simpson 44-141-201-0000

Children's Hospital - Sheffield *Recruiting*
Sheffield,  England,  S10 2TH
United Kingdom
Recruiting Mary  Gerrard 00-44-0114-271-7229

Leicester Royal Infirmary *Recruiting*
Leicester,  England,  LE1 5WW
United Kingdom
Recruiting Rosemary  Shannon 44-116-254-1414

Royal Belfast Hospital for Sick Children *Recruiting*
Belfast,  Northern Ireland,  BT12 6BE
United Kingdom
Recruiting Anthony  Mccarthy 44-289-063-3631

Our Lady's Hospital for Sick Children *Recruiting*
Crumlin,  ,  12
Ireland
Recruiting Fin  Breatnach 353-1-409-6659

St. James's University Hospital *Recruiting*
Leeds,  England,  LS9 7TF
United Kingdom
Recruiting Adam  Glaser 44-113-206-4986

Aberdeen Royal Infirmary *Recruiting*
Aberdeen,  Scotland,  AB25 2ZN
United Kingdom
Recruiting D.J.  King 44-1224-681-818

Oxford Radcliffe Hospital *Recruiting*
Oxford,  England,  0X3 9DU
United Kingdom
Recruiting Kate  Wheeler 44-186-522-1066

Newcastle Upon Tyne Hospitals NHS Trust *Recruiting*
Newcastle upon Tyne,  England,  NE7 7DN
United Kingdom
Recruiting Andrew  J. Pearson 44-191-232-5131 ext. 24101

Saint Bartholomew's Hospital *Recruiting*
London,  England,  EC1A 7BE
United Kingdom
Recruiting Judith  Kingston 44-20-7943-1339

Manchester Children's Hospitals (NHS Trust) *Recruiting*
Manchester,  England,  M27 1HA
United Kingdom
Recruiting Bernadette  Brennan 44-161-727-2222


Additional Information:
Study ID Numbers:
  CDR0000068944;  EU-20124,UKCCSG-SC-1999-01
Study Start Date: 
Record last reviewed: February 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00024453

Other Infection Studies:
1. Voriconazole With or Without Interferon gamma in Treating Patients With Aspergillosis or Other Fungal Infections

2. Anidulafungin in Treating Immunocompromised Children With Neutropenia

3. Levofloxacin to Prevent Infection Following Chemotherapy in Treating Patients With Solid Tumors or Lymphoma

4. Moxifloxacin Compared With Ciprofloxacin/Amoxicillin in Treating Fever and Neutropenia in Patients With Cancer

5. Detection and Characterization of Host Defense Defects

Related Studies:

Other Infection Clinical Trials
Other England Clinical Trials
Other London Clinical Trials

Teicoplanin in Treating Septicemia in Patients Who Are Receiving Chemotherapy Through a Central Venous Catheter

Modify your Search

  Other Infection Clinical Trials
  Other England Clinical Trials
  Other London Clinical Trials


Warning: include(/var/www/cgi-bin/traxis/counter.php) [function.include]: failed to open stream: No such file or directory in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103

Warning: include() [function.include]: Failed opening '/var/www/cgi-bin/traxis/counter.php' for inclusion (include_path='.:/usr/local/lib/php') in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103