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Study of the Safety and Efficacy of an Investigational Drug in Adult Patients with Multiple Myeloma



Study of the Safety and Efficacy of an Investigational Drug in Adult Patients with Multiple Myeloma

For Condition: Multiple Myeloma
Status: Completed
Sponsor(s): Pfizer ,
Synopsis: The primary goal of the study is to determine the best dose of an investigational drug to give to patients with multiple myeloma and to evaluate the investigational drug's effectiveness as a treatment for mulitiple myeloma.
Details:
Eligibility:
Study Type:
  Interventional, Treatment
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Other specific inclusion/exclusion criteria may apply. In order to determine eligibility, further examination by the investigator is necessary. Inclusion Criteria: - Eligible patients must be at least 18 years of age with a diagnosis of multiple myeloma including elevated M-blood/urine protein or a tumor that can be evaluated by the doctor during the investigational drug's treatment. - The patient's multiple myeloma must have gotten worse during/after previous chemotherapy was given. - Any side-effects from prior chemotherapy must have subsided - Blood and urine tests must show adequate bone marrow, liver, and kidney function. Exclusion Criteria: Any of the following will exclude patients from study participation: - indolent or smoldering myeloma or localized plasmacytoma - hyperviscosity syndrome - irradiation to 25% or more of bone marrow - prior high dose chemotherapy with bone marrow or stem cell support - current participation in other clinical trials - pregnant or breast-feeding women - known HIV-positive or AIDS-related illness - patients planning to have radiation therapy or surgery that would interrupt study therapy in the next 6 months.
Total Enrollment: 

Location and Contact Information:

Research Center
Marshfield,  Wisconsin,  54449
United States
 

Research Center
Los Angeles,  California,  90033
United States
 

Research Center
Los Angeles,  California,  90048
United States
 

Research Center
Rancho Mirage,  California,  92270
United States
 

Research Center
Cleveland,  Ohio,  44106
United States
 


Additional Information:
Study ID Numbers:
  196-ONC-0100-006; 
Study Start Date: 
Record last reviewed: March 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00036140

Other Multiple Myeloma Studies:
1. Comparing Treatments for Multiple Myeloma

2. T Cell Immunotherapy for Multiple Myeloma Patients Undergoing a Bone Marrow Transplant

3. Immunotherapy in Treating Patients Who Are Undergoing Bone Marrow or Peripheral Stem Cell Transplantation

4. Suberoylanilide Hydroxamic Acid in Treating Patients With Advanced Solid Tumors That Have Not Responded to Previous Therapy

5. Pyroxamide in Treating Patients With Advanced Cancer

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Study of the Safety and Efficacy of an Investigational Drug in Adult Patients with Multiple Myeloma

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