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Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults with Repaired or Palliated Conotruncal Cardiac Defects Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for certified health advice, travels to or treatment by using a genuine physician. We are not physicians. Always consult your dr. on Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults with Repaired or Palliated Conotruncal Cardiac Defects conditions. Clinical Trials Search.org is a site committed to listing clinical research studies in human subjects. Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults with Repaired or Palliated Conotruncal Cardiac Defects Clinical research trials and Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults with Repaired or Palliated Conotruncal Cardiac Defects health trials occur in hundreds of cities throughout the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectivity of new drugs. The propose of the studies / undertakings is to resolve certain human health questions. Clinical trials are a popular means for physicians, government agencies, and private sector companies to locate treatments for all sorts of conditions, including Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults with Repaired or Palliated Conotruncal Cardiac Defects. Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults with Repaired or Palliated Conotruncal Cardiac Defects Clinical Trials and other clinical trials permit volunteers to acquire medical treatment choices before they are available to the masses. Some times the test subjects obtain professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults with Repaired or Palliated Conotruncal Cardiac Defects clinical trial. Participants oftentimes recieve the most expert healthcare available for their Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults with Repaired or Palliated Conotruncal Cardiac Defects condition. Hazards are a reality, however, and can include extra or frequent physician visits, health risks (potentially life-endangering), and/or the treatment being uneffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.
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Home > "S" Clinical Trials Conditions > Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults with Repaired or Palliated Conotruncal Cardiac Defects Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults with Repaired or Palliated Conotruncal Cardiac Defects
Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults with Repaired or Palliated Conotruncal Cardiac Defects
For Condition: Tetralogy of Fallot,Pulmonary Valve Stenosis,Pulmonary Atresia,Hypoparathyroidism,Conotruncal Cardiac Defects,Heart Defects, Congenital
Status: Completed
Sponsor(s): National Center for Research Resources (NCRR) , Children's Memorial Hospital, Chicago
Synopsis: OBJECTIVES: I. Identify latent hypoparathyroidism in normocalcemic adult survivors with repaired conotruncal cardiac defects, by evaluating parathyroid gland secretory function after induced hypocalcemia. II. Determine the relationship of parathyroid hormone secretion to microdeletions in the same region of chromosome 22q11 as found in patients with DiGeorge anomaly.
Details: PROTOCOL OUTLINE: Patients are given sodium citrate over a 2 hour infusion on day 1. Blood is drawn at times -30, -15, 0, and every 10 minutes thereafter during the infusion. On day 2, patients are given calcium gluconate over a 2 hour infusion. Blood is drawn at times -30, -15, 0, and every 10 minutes thereafter during the infusion.
Eligibility:
Study Type: Observational, Screening
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: - Diagnostically shown repaired or palliated conotruncal cardiac defects, including tetralogy of Fallot with pulmonary stenosis or pulmonary atresia, truncus arteriosus, or interrupted aortic arch type B
Total Enrollment: 150
Location and Contact Information:
Overall Study Official:
CraigLangman, Study Chair, Children's Memorial Hospital, Chicago
Additional Information:
Study ID Numbers: 199/11936; NU-553
Study Start Date: July 1995
Record last reviewed: January 2001
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00004361
Other Pulmonary Atresia Studies:
1. Studies of Elevated Parathyroid Activity
2. Study to Evaluate the Effects of Zemplar Injection and Calcijex on Intestinal Absorption of Calcium
3. Treatment of Hypoparathyroidism with Synthetic Human Parathyroid Hormone 1-34
4. Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults with Repaired or Palliated Conotruncal Cardiac Defects
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Study of the Relationship Between Calcium Levels and Intact Parathyroid Hormone (iPTH) in Adults with Repaired or Palliated Conotruncal Cardiac Defects
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