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Study of OSI-211 vs. Topotecan in Patients with Relapsed Epithelial Ovarian Cancer



Study of OSI-211 vs. Topotecan in Patients with Relapsed Epithelial Ovarian Cancer

For Condition: Ovarian Neoplasms
Status: Recruiting
Sponsor(s): OSI Pharmaceuticals ,
Synopsis: The purpose of this study is to estimate the efficacy and safety of OSI-211 and topotecan in patients with relapsed epithelial ovarian cancer.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Open Label, Active Control, Parallel Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/
Genders: Female
Protocol Entry Criteria: Inclusion Criteria: - Confirmed relapsed ovarian cancer. - Measurable disease greater than or equal to 20 mm (or greater than or equal to 10 mm on spiral CT scan). - One or two prior regimens of chemotherapy. At least one regimen must have contained cisplatin or carboplatin. - At least three weeks since prior chemotherapy and recovery from any related toxicities. - At least four weeks since prior radiotherapy and recovery from any related toxicities.
Total Enrollment: 80

Location and Contact Information:

Royal Surrey County Hospital *Recruiting*
Guildford, Surrey,  ,  GU2 7XX
United Kingdom
Recruiting OSIP  Information (800) 572-1932

The Sarah Cannon Cancer Center, Centennial Medical Center *Recruiting*
Nashville,  Tennessee,  37203
United States
Recruiting OSIP  Information 800-572-1932

Beatson Oncology Centre *Recruiting*
Glasgow,  ,  G11 6NT
United Kingdom
Recruiting OSIP  Information (800) 572-1932

Northern Centre for Cancer Research, Newcastle General Hospital *Recruiting*
Newcastle upon Tyne,  ,  NE4 6BE
United Kingdom
Recruiting OSIP  Information (800) 572-1932

Royal Marsden NHS Trust *Recruiting*
London,  ,  SW3 6JJ
United Kingdom
Recruiting OSIP  Information (800) 572-1932

Taunton & Somerset Hospital *Recruiting*
Taunton,  ,  TA1 5DA
United Kingdom
Recruiting OSIP  Information (800) 572-1932

St Chad's Unit *Recruiting*
Birmingham,  ,  B18 7QH
United Kingdom
Recruiting OSIP  Information (800) 572-1932

NYU- Kaplan Comprehensive Cancer Center *Recruiting*
New York City,  New York,  10016
United States
Recruiting OSIP  Information 800-572-1932

Mount Vernon Hospital *Recruiting*
Northwood, Middlesex,  ,  HA6 2RN
United Kingdom
Recruiting OSIP  Information (800) 572-1932

CRC Department of Medical Oncology *Recruiting*
Sutton Surrey,  ,  SM2 5PT
United Kingdom
Recruiting OSIP  Information (800) 572-1932

Medical Oncology Unit, Torbay District General Hospital *Recruiting*
Torquay,  ,  TQ2 7AA
United Kingdom
Recruiting OSIP  Information (800) 572-1932


Additional Information:
Study ID Numbers:
  110-20; 
Study Start Date: September 2002
Record last reviewed: November 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00046800

Other Ovarian Neoplasms Studies:
1. Removal of the ovaries/fallopian tubes and CA-125 Screening to Reduce the Risk of Ovarian Cancer in Women at Increased Genetic Risk

2. EPO906 Therapy in Patients with Advanced Ovarian, Primary Fallopian, or Primary Peritoneal Cancer

3. A Safety and Effectiveness Study of Aroplatin in Patients with Advanced Solid Malignancies

4. Safety/Efficacy Study of SGN-15 (Antibody-Drug Conjugate) Combined with Gemcitabine in Patients with Ovarian Cancer

5. Study of OSI-211 vs. Topotecan in Patients with Relapsed Epithelial Ovarian Cancer

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