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Study of LymphoStat-B (monoclonal anti-BLyS antibody) in Subjects with Rheumatoid Arthritis (RA) Clinical Trials References presented on Clinical Trials Search is not intended to be a substitute for proven healthcare advice, trips or professional assistance by using a real medical. We aren't mDs. Always confer with your physician about Study of LymphoStat-B (monoclonal anti-BLyS antibody) in Subjects with Rheumatoid Arthritis (RA) conditions. Clinical Trials Search.org is a website devoted to listing clinical research studies in human subjects. Study of LymphoStat-B (monoclonal anti-BLyS antibody) in Subjects with Rheumatoid Arthritis (RA) Clinical research trials and Study of LymphoStat-B (monoclonal anti-BLyS antibody) in Subjects with Rheumatoid Arthritis (RA) medical trials take place in hundreds of localities across the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials usually evaluate the effectualness of new does drugs. The purpose of the studies / projects is to solve specific human health questions. Clinical trials are a popular way for physicians, government agencies, and private sector companies to discover treatments for all sorts of conditions, such as Study of LymphoStat-B (monoclonal anti-BLyS antibody) in Subjects with Rheumatoid Arthritis (RA). Study of LymphoStat-B (monoclonal anti-BLyS antibody) in Subjects with Rheumatoid Arthritis (RA) Clinical Trials and other clinical trials permit volunteers to access healthcare treatment choices before they are available to the general public. Some times the subjects recieve professional assistance for without cost, and every now and again they are compensated for their time. Sometimes there is a cost for a Study of LymphoStat-B (monoclonal anti-BLyS antibody) in Subjects with Rheumatoid Arthritis (RA) clinical trial. Subjects often receive the most expert healthcare possible for their Study of LymphoStat-B (monoclonal anti-BLyS antibody) in Subjects with Rheumatoid Arthritis (RA) condition. Risks are a reality, nevertheless, and could include additional or frequent dr. calls, healthcare dangers (perhaps life-jeopardising), and/or the treatment being ineffective. Trials are federally governed with stern guidelines to protect clinical trials subjects.
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Home > "S" Clinical Trials Conditions > Study of LymphoStat-B (monoclonal anti-BLyS antibody) in Subjects with Rheumatoid Arthritis (RA)  Study of LymphoStat-B (monoclonal anti-BLyS antibody) in Subjects with Rheumatoid Arthritis (RA)
Study of LymphoStat-B (monoclonal anti-BLyS antibody) in Subjects with Rheumatoid Arthritis (RA)
For Condition: Arthritis, Rheumatoid
Status: Recruiting
Sponsor(s): Human Genome Sciences ,
Synopsis: The purpose of this study is to evaluate the safety and efficacy of 3 different doses of LymphoStat-B, administered in addition to standard therapy, in subjects with RA.
Details:
Eligibility:
Study Type: Interventional, Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/65 Years
Genders: Both
Protocol Entry Criteria: Primary Inclusion Criteria: - Diagnosis of RA for at least 1 year - Failed at least 1 disease modifying anti-rheumatic drug (DMARD) due to toxicity or lack of efficacy. These drugs must include 1 or more of the following: methotrexate, parenteral gold, sulfasalazine, leflunomide, and TNFα inhibitors (infliximab, etanercept or adalimumab) - Active RA disease of at least moderate disease activity - Be on a stable RA treatment regimen for at least the past 60 days (for DMARDS); if on non-steroidal anti-inflammatory drugs (NSAIDs) or steriods these must be at a stable dose for the last 30 days Primary Exclusion Criteria: - Received a non-FDA approved investigational agent within the last 28 days - Currently receiving or received within the last 60 days the following: TNFα-inhibitors (infliximab, etanercept, adalimumab) or interleukin-1 receptor antagonist (anakinra) - Currently receiving or received within the last 6 months the following: anti-CD20 antibody(rituximab)or cyclophosphamide - Steroid injection into any joint within the last 30 days - History of hypogammaglobulinemia or IgA deficiency - History of chronic infection that has been active within last 6 months, or herpes zoster within last 90 days, or any infection requiring hospitalization or intravenous medication within last 60 days - HIV, Hepatitis-B, Heptatitis-C
Total Enrollment:
Location and Contact Information:
Rheumatic Disease Associates *Recruiting*
Willow Grove, Pennsylvania, 19090
United States
Recruiting
Tampa Medical Group, P.A. *Recruiting*
Tampa, Florida, 33614
United States
Recruiting
Arthritis and Rheumatic Disease Specialties *Not yet recruiting*
Aventura, Florida, 33180
United States
Not yet recruiting
Stanford University School of Medicine *Recruiting*
Palo Alto, California, 94304
United States
Recruiting
The University of Michigan Health System *Not yet recruiting*
Ann Arbor, Michigan, 48109-0358
United States
Not yet recruiting
Scripps Clinic *Not yet recruiting*
LaJolla, California, 92037
United States
Not yet recruiting
SUNY-Downstate Medical Center *Not yet recruiting*
Brooklyn, New York, 11203
United States
Not yet recruiting
Thomas Jefferson University Hospital *Not yet recruiting*
Philadelphia, Pennsylvania, 19107
United States
Not yet recruiting
UT Southwestern Medical Center at Dallas *Not yet recruiting*
Dallas, Texas, 75390-8884
United States
Not yet recruiting
UCDMC *Not yet recruiting*
Sacramento, California, 95817-1418
United States
Not yet recruiting
Arthritis and Rheumatic Diseases Clinic *Not yet recruiting*
Weber, Utah, 84403
United States
Not yet recruiting
Boling Clinical Trials *Recruiting*
Rancho Cucamonga, California, 91730
United States
Recruiting
Arthritis Center of Nebraska *Recruiting*
Lincoln, Nebraska, 68506
United States
Recruiting
Rockford Clinic *Not yet recruiting*
Rockford, Illinois, 61103
United States
Not yet recruiting
Research Associates of North Texas *Not yet recruiting*
Dallas, Texas, 75246
United States
Not yet recruiting
Arthritis Care Center, Inc. *Recruiting*
San Jose, California, 95126-1650
United States
Recruiting
Ochsner Clinic Foundation *Recruiting*
Baton Rouge, Louisiana, 70809
United States
Recruiting
Arthritis Associates & Osteoporosis Center Of Colorado Springs *Not yet recruiting*
Colorado Springs, Colorado, 80910
United States
Not yet recruiting
Evergreen Clinical Reserach *Recruiting*
Edmonds, Washington, 98026-8047
United States
Recruiting
Washington University in St. Louis *Not yet recruiting*
St. Louis, Missouri, 63110
United States
Not yet recruiting
University of Southern California *Not yet recruiting*
Los Angeles, California, 90033
United States
Not yet recruiting
University of Pittsburgh School of Medicine & ASPH *Not yet recruiting*
Pittsburgh, Pennsylvania, 15261
United States
Not yet recruiting
Gundersen Clinic, Ltd. *Not yet recruiting*
La Crosse, Wisconsin, 54610
United States
Not yet recruiting
The Osteoporosis and Arthritis Clinical Trial Center *Recruiting*
Cumberland, Maryland, 21502
United States
Recruiting
Northwestern University Medical School *Not yet recruiting*
Chicago, Illinois, 60611
United States
Not yet recruiting
Arthritis and Osteoporosis Center *Not yet recruiting*
Concord, New Hampshire, 03301
United States
Not yet recruiting
Rheumatic Disease Center *Not yet recruiting*
Glendale, Wisconsin, 53217
United States
Not yet recruiting
The Medical College of Wisconsin , Inc *Not yet recruiting*
Milwaukee, Wisconsin, 53226
United States
Not yet recruiting
Arthritis Northwest Rheumatology *Recruiting*
Spokane, Washington, 99204
United States
Recruiting
Arthritis Clinic and Carolina Bone and Joint *Recruiting*
Charlotte, North Carolina, 28210
United States
Recruiting
Arthritis Clinic of Northern Virginia, P.C. *Not yet recruiting*
Arlington, Virginia, 22205
United States
Not yet recruiting
Arizona Arthritis Research *Not yet recruiting*
Paradise Valley, Arizona, 85253
United States
Not yet recruiting
University of North Carolina at Chapel Hill *Not yet recruiting*
Chapel Hill, North Carolina, 27599-7280
United States
Not yet recruiting
Kentuckiana Center for Better Bone and Joint Health *Not yet recruiting*
Louisville, Kentucky, 40202
United States
Not yet recruiting
Johns Hopkins Hospital *Not yet recruiting*
Baltimore, Maryland, 21287
United States
Not yet recruiting
Mayo Clinic *Not yet recruiting*
Rochester, Minnesota, 55905
United States
Not yet recruiting
Edmonds Rheumatology Associates *Not yet recruiting*
Edmonds, Washington, 98026-8047
United States
Not yet recruiting
Oklahoma Center For Arthritis Therapy & Research *Not yet recruiting*
Tulsa, Oklahoma, 74114
United States
Not yet recruiting
University of Arizona *Not yet recruiting*
Tucson, Arizona, 85724
United States
Not yet recruiting
Washington Hospital Center *Not yet recruiting*
Washington D.C., District of Columbia, 20010
United States
Not yet recruiting
Strafford Medical Associates, P.A. *Recruiting*
Dover, New Hampshire, 03820
United States
Recruiting
North Shore University Hospital *Not yet recruiting*
Manhasset, New York, 11030
United States
Not yet recruiting
Oklahoma Medical Research Foundation *Not yet recruiting*
Oklahoma City, Oklahoma, 73104
United States
Not yet recruiting
Medical Specialists *Recruiting*
Munster, Indiana, 46321
United States
Recruiting
Marshfield Medical Research Foundation *Not yet recruiting*
Wausau, Wisconsin, 54401
United States
Not yet recruiting
Cedars-Sinai Medical Center *Not yet recruiting*
Los Angeles, California, 90048
United States
Not yet recruiting
Arthritis Centers of Texas *Recruiting*
Dallas, Texas, 75246
United States
Recruiting
Center for Rhematology and Bone Research *Recruiting*
Wheaton, Maryland, 20902
United States
Recruiting
McBride Clinic *Recruiting*
Oklahoma City, Oklahoma, 73101
United States
Recruiting
Radiant Research Boise *Recruiting*
Boise, Idaho, 83704
United States
Recruiting
University of Alabama at Birmingham *Not yet recruiting*
Birmingham, Alabama, 35294-0006
United States
Not yet recruiting
Jacobi Medical Center *Not yet recruiting*
Bronx, New York, 10461
United States
Not yet recruiting
Wake Forest University School of Medicine *Not yet recruiting*
Winston Salem, North Carolina, 27157
United States
Not yet recruiting
Additional Information:
Study ID Numbers: LBRA01;
Study Start Date:
Record last reviewed: January 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00071812
Other Arthritis, Rheumatoid Studies:
1. Methotrexate Alone Versus Combination of Methotrexate and Subcutaneous Fludarabine for Severe Rheumatoid Arthritis: Safety, Tolerance and Efficacy
2. Study of LymphoStat-B (monoclonal anti-BLyS antibody) in Subjects with Rheumatoid Arthritis (RA)
3. Safety Study of SCIO-469 to treat Patients with Active Rheumatoid Arthritis Receiving Methotrexate
4. The Pathogenesis of Inflammatory Synovitis: A Study of Early Arthritis
5. A Rheumatoid Arthritis (RA) Study Treating Signs and Symptoms of RA in People With RA & Receiving Methotrexate
Related Studies:
Other Arthritis, Rheumatoid Clinical Trials
Other Texas Clinical Trials
Other Dallas Clinical Trials
Study of LymphoStat-B (monoclonal anti-BLyS antibody) in Subjects with Rheumatoid Arthritis (RA)
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