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Study of Genotype and Phenotype in Patients With Alpha 1-Antitrypsin Deficiency



Study of Genotype and Phenotype in Patients With Alpha 1-Antitrypsin Deficiency

For Condition: alpha 1-Antitrypsin Deficiency
Status: Terminated
Sponsor(s): National Center for Research Resources (NCRR) , Children's Hospital of Pittsburgh
Synopsis: OBJECTIVES: I. Establish cell lines from patients with alpha 1-antitrypsin deficiency in order to examine genetic traits that predispose to liver injury.
Details: PROTOCOL OUTLINE: Patients undergo blood draw and skin biopsy. Cells are isolated from patients' blood and skin, cell lines are established, and genetic traits are examined.
Eligibility:
Study Type:
  Observational, Screening
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: - Alpha 1-antitrypsin deficiency
Total Enrollment: 160

Location and Contact Information:

Overall Study Official:
DavidPerlmutter,  Study Chair,  Children's Hospital of Pittsburgh

Children's Hospital of Pittsburgh
Pittsburgh,  Pennsylvania,  15213
United States
 


Additional Information:
Study ID Numbers:
  199/14810;  WUSM-930603
Study Start Date: March 1999
Record last reviewed: May 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00005098

Other Alpha 1-Antitrypsin Deficiency Studies:
1. Characterization of the Pathobiology of Early Lung Destruction in Alpha 1-Antitrypsin Deficient Individuals

2. 4-PBA: Will it increase the level of Alpha 1-Antitrypsin(AAT) in persons with AAT deficiency?

3. Study of Genotype and Phenotype in Patients With Alpha 1-Antitrypsin Deficiency

Related Studies:

Other alpha 1-Antitrypsin Deficiency Clinical Trials
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Other Pittsburgh Clinical Trials

Study of Genotype and Phenotype in Patients With Alpha 1-Antitrypsin Deficiency

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