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Sleep Disorders of Patients with Diseases of the Nervous System



Sleep Disorders of Patients with Diseases of the Nervous System

For Condition: Hypersomnia,Narcolepsy,Nervous System Disease,Sleep Disorder
Status: Recruiting
Sponsor(s): National Institute of Neurological Disorders and Stroke (NINDS) ,
Synopsis: The purpose of this study is to assist training doctors about different diseases of the nervous system affecting sleep. Patients selected to participate in this study will have any of a variety of sleep disorders. They will undergo several tests including an overnight recording of brain activity, eye movement, leg movement, breathing, heart rate, and other measures. Results of these tests will be used to better understand diseases causing sleep disorders and may be used to develop better treatments for them.
Details: The objective of this protocol is to provide an opportunity of a broad experience of various neurological sleep disorders for the purpose of training clinical associates who are eligible for sitting in the Board examination of the Added Qualification of Clinical Neurophysiology administered by the American Board of Psychiatry and Neurology. This protocol is to supplement small accrual of research patients who are referred from within the NIH.
Eligibility:
Study Type:  Interventional, Training
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: IINCLUSION CRITERIA: Patients 5 years of age and older, with the following referring diagnoses: Narcolepsy Hypersomnia REM behavior disorder Frontal nocturnal dystonia Restless legs syndrome Insomnia Parasomnia Nocturnal epileptic seizure Nocturnal movement disorder Sleep-related diagnostic dilemma Sleep apnea associated with neurological disorders Patients who are ambulatory and who are able to comply with the study procedures. Patients who are able to understand and sign the informed consent. (Parent or guardian for minors). EXCLUSION CRITERIA: Patients who have been diagnosed with acute and progressive neurological disorders. Patients who are unable to comply with the study procedures and require other than standard care.
Total Enrollment: 80

Location and Contact Information:

National Institute of Neurological Disorders and Stroke (NINDS) *Recruiting*
Bethesda,  Maryland,  20892
United States
Recruiting Patient  and Public Liaison Office 1-800-411-1222


Additional Information:
Study ID Numbers:  970070;  97-N-0070
Study Start Date: December 4, 1996
Record last reviewed: December 17, 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001664

Other Nervous System Disease Studies:
1. Safety and Efficacy Study of CEP-10953 in the Treatment of Excessive Sleepiness Associated with Narcolepsy

2. Safety and efficacy of Xyrem oral solution (sodium oxybate) compared with placebo in narcoleptic patients

3. Trial Comparing Effects of Xyrem taken Orally and Modafinil with Placebo in Treating Daytime Sleepiness in Narcolepsy

4. Sleep Disorders of Patients with Diseases of the Nervous System

5. CEP-10953 for Treatment of Narcolepsy, Obstructive Sleep Apnea/Hypopnea Syndrome, or Chronic Shift Work Sleep Disorder

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