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Screening Protocol for Patients with Neurologic Disorders with Muscle Stiffness Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for qualified medical advice, visits or professional assistance by using a real mD. We are not docs. Always confer with your physician about Screening Protocol for Patients with Neurologic Disorders with Muscle Stiffness conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Screening Protocol for Patients with Neurologic Disorders with Muscle Stiffness Clinical research trials and Screening Protocol for Patients with Neurologic Disorders with Muscle Stiffness health trials occur in many of cities throughout the US. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally evaluate the effectivity of new does drugs. The intent of the studies / undertakings is to resolve particular human health questions. Clinical trials are a popular way for physicians, government agencies, and private sector companies to detect remedies for all sorts of conditions, including Screening Protocol for Patients with Neurologic Disorders with Muscle Stiffness. Screening Protocol for Patients with Neurologic Disorders with Muscle Stiffness Clinical Trials and other clinical trials permit volunteers to obtain healthcare treatment alternatives before they are available to the masses. Most times the participants undergo professional assistance for without cost, and occasionally they are compensated for their time. Occasionally there is a cost for a Screening Protocol for Patients with Neurologic Disorders with Muscle Stiffness clinical trial. Test subjects typically receive the most expert healthcare available for their Screening Protocol for Patients with Neurologic Disorders with Muscle Stiffness condition. Dangers are a reality, however, and may include more or frequent mD visits, healthcare dangers (perhaps life-endangering), and/or the treatment being ineffectual. Trials are federally regulated with rigid guidelines to protect clinical trials patients.
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Home > "S" Clinical Trials Conditions > Screening Protocol for Patients with Neurologic Disorders with Muscle Stiffness  Screening Protocol for Patients with Neurologic Disorders with Muscle Stiffness
Screening Protocol for Patients with Neurologic Disorders with Muscle Stiffness
For Condition: Neurological Disorder,Muscle Cramp
Status: Recruiting
Sponsor(s): National Institute of Neurological Disorders and Stroke (NINDS) ,
Synopsis: This study will evaluate patients with muscle stiffness for possible participation in current or future research studies. It will determine the cause of muscle stiffness or cramps and measure the severity of symptoms. Children and adults with muscle stiffness, cramps or spasticity may be eligible for this study. Participants will provide a medical history and have a physical examination. In addition to the standard neurological examination, patients may be tested on how long it takes to make some movements, such as walking or tapping on a keyboard. To determine the cause of the muscle problem, patients may also undergo blood tests and the following procedures: Magnetic resonance imaging (MRI) - MRI uses a strong magnetic field and radio waves to show structural and chemical changes in tissue. The patient lies on a table in a space enclosed by a metal cylinder (the scanner) for about 45 minutes, lying very still for 10 to 15 minutes at a time. The patient can communicate with the technician at all times during the procedure. Electromyography (EMG) and nerve conduction studies - EMG measures the electrical activity of the muscles. A needle is inserted into a muscle to record its electrical activity. Nerve conduction studies measure the speed with which nerves conduct electrical impulses. A wire is taped on the skin over a nerve to deliver a small electrical stimulus and another wire taped to the skin records the impulses. Patients will also be asked to fill out a health questionnaire no more than once a year. The information will be used to determine their eligibility for new studies.
Details: The purpose of this protocol is to perform a screening evaluation of patients referred with muscle stiffness and to determine the cause of the abnormal muscle contraction. Muscle stiffness can be caused by abnormalities of the muscle itself, of peripheral nerves, or by disorders of the central nervous system. Diagnostic tests such as Nerve conduction studies and electromyography can help to determine the site of abnormality. This protocol is intended to identify patients for participation in future investigations of how the spinal and peripheral motor system coordinate movement.
Eligibility:
Study Type: Observational, Screening
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: INCLUSION CRITERIA Adult or pediatric patients with involuntary muscle contraction, muscle cramps, or spasticity. EXCLUSION CRITERIA Non-neurological disorders that produce muscle stiffness, such as fasciitis or rheumatological conditions. Disorders in which pain limits the ability to move muscles, such as fibromyalgia or complex regional pain syndromes. Profound weakness of voluntary movement. Anticoagulation (will be an exclusion for needle EMG). Implanted devices or metal fragments in the brain or spinal cord will be an exclusion for MRI scanning.
Total Enrollment: 60
Location and Contact Information:
National Institute of Neurological Disorders and Stroke (NINDS) *Recruiting*
Bethesda, Maryland, 20892
United States
Recruiting Patient and Public Liaison Office 1-800-411-1222
Additional Information:
Study ID Numbers: 010145; 01-N-0145
Study Start Date: April 11, 2001
Record last reviewed: February 27, 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00015444
Other Muscle Cramp Studies:
1. Screening Protocol for Patients with Neurologic Disorders with Muscle Stiffness
Related Studies:
Other Muscle Cramp Clinical Trials
Other Maryland Clinical Trials
Other Bethesda Clinical Trials
Screening Protocol for Patients with Neurologic Disorders with Muscle Stiffness
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