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Safety and Efficacy Study of RTS,S AS02A/AS01B Vaccine to Prevent Malaria



Safety and Efficacy Study of RTS,S AS02A/AS01B Vaccine to Prevent Malaria

For Condition: Malaria
Status: Recruiting
Sponsor(s): Walter Reed Army Institute of Research (WRAIR) , GlaxoSmithKline Biologicals
Synopsis: This is a double blinded study where 2 test vaccines will be evaluated to see if they protect persons who have never had malaria against malaria infection when bitten by mosquitoes.
Details:
Eligibility:
Study Type:
  Interventional, Prevention, Randomized, Double-Blind, Active Control, Single Group Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/45 Years
Genders: Both
Protocol Entry Criteria: - Be in good general health; not pregnant or planning pregnancy - Have no past history of malaria; no exposure to malaria in past 12 months - Have never received an investigational malaria vaccine - Have no past history of allergic reaction to previous immunization - Have negative blood tests for HIV and specific types of hepatitis - Be able to participate for 4-15 months
Total Enrollment: 104

Location and Contact Information:

Walter Reed Army Institute of Research *Recruiting*
Silver Spring,  Maryland,  20910
United States
Recruiting Oman  Salazar 866-856-3259


Additional Information:
Study ID Numbers:
  1032;  257049/027,Malaria-027
Study Start Date: December 2003
Record last reviewed: March 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00075049

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2. Evaluation, Treatment and Monitoring of Patients with a Known or Suspected Parasitic Infection

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