Search Clinical Trials
By Condition
By Location (USA)
By Location (Other)
By Sponsor
Resources
Privacy Policy
About Us
Disclaimer
Safety and efficacy study of Interferon gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for qualified medical advice, visits or professional assistance by using a real mD. We are not docs. Always confer with your physician about Safety and efficacy study of Interferon gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Safety and efficacy study of Interferon gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis Clinical research trials and Safety and efficacy study of Interferon gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis health trials occur in many of cities throughout the US. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally evaluate the effectivity of new does drugs. The intent of the studies / undertakings is to resolve particular human health questions. Clinical trials are a popular way for physicians, government agencies, and private sector companies to detect remedies for all sorts of conditions, including Safety and efficacy study of Interferon gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis. Safety and efficacy study of Interferon gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis Clinical Trials and other clinical trials permit volunteers to obtain healthcare treatment alternatives before they are available to the masses. Most times the participants undergo professional assistance for without cost, and occasionally they are compensated for their time. Occasionally there is a cost for a Safety and efficacy study of Interferon gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis clinical trial. Test subjects typically receive the most expert healthcare available for their Safety and efficacy study of Interferon gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis condition. Dangers are a reality, however, and may include more or frequent mD visits, healthcare dangers (perhaps life-endangering), and/or the treatment being ineffectual. Trials are federally regulated with rigid guidelines to protect clinical trials patients.

Home > "S" Clinical Trials Conditions > Safety and efficacy study of Interferon gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis

Safety and efficacy study of Interferon gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis



Safety and efficacy study of Interferon gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis

For Condition: Liver Fibrosis,Cirrhosis
Status: Completed
Sponsor(s): InterMune ,
Synopsis: The purpose of this research study is to test the safety and effectiveness of Interferon gamma-1b (IFN-g 1b) injected subcutaneously (under the skin) for the treatment of advanced liver fibrosis and cirrhosis in patients with chronic hepatitis C infections. IFN-g 1b is not currently approved for the treatment of liver fibrosis.
Details: This study will evaluate the safety and tolerability of IFN-g 1b in patients with advanced liver fibrosis and cirrhosis due to hepatitis C. This study will also evaluate whether IFN-g 1b is effective in reducing the amount of fibrosis in the liver.
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Double-Blind, Placebo Control, Single Group Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/75 Years
Genders: Both
Protocol Entry Criteria: - Men or women 18 to 75 years - Chronic hepatitis C infection based on a history of positive anti-HCV antibody and/or HCV RNA - History of prior treatment with interferon-a-based therapies or an assessment by the investigator that the patient would not benefit from interferon-a-based therapy or that treatment with interferon-a is contraindicated - Stage 4, 5 or 6 liver fibrosis according to the Ishak scoring system. - Cannot have presence of clinically evident ascites requiring active diuretic therapy, history of or therapy for hepatic encephalopathy, or history of GI variceal bleeding within the last 2 years (diuretic therapy of stable mild-to-moderate peripheral edema is permitted) - Must meet minimum blood chemistry requirements - Cannot have unstable or uncontrolled thyroid disease - Cannot have a variety of other diseases (listed in protocol - Other conditions for enrollment exist which would be discussed with a Clinician upon screening for the study.
Total Enrollment: 500

Location and Contact Information:


Additional Information:
Study ID Numbers:
  GILF-001; 
Study Start Date: September 2001
Record last reviewed: July 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00043303

Other Liver Fibrosis Studies:
1. Prevention of Disease Progress in Chronic HepC Pts Significant Liver Fibrosis who failed PEG-Intron + Rebetol in P02370

2. PEG-Intron Plus Rebetol Treatment of Chronic Hepatitis C Subjects Who Failed Response to alpha-Interferon Plus Ribavirin

3. Safety and efficacy study of Interferon gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis

Related Studies:

Other Liver Fibrosis Clinical Trials
Other Clinical Trials
Other Clinical Trials

Safety and efficacy study of Interferon gamma-1b in hepatitis C patients with liver fibrosis or cirrhosis

Modify your Search

  Other Liver Fibrosis Clinical Trials
  Other Clinical Trials
  Other Clinical Trials


Warning: include(/var/www/cgi-bin/traxis/counter.php) [function.include]: failed to open stream: No such file or directory in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103

Warning: include() [function.include]: Failed opening '/var/www/cgi-bin/traxis/counter.php' for inclusion (include_path='.:/usr/local/lib/php') in /home/cts/domains/clinicaltrialssearch.org/public_html/index.php on line 103