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Home > "S" Clinical Trials Conditions > Safety and Efficacy of Natalizumab in Combination with Avonex in the Treatment of Multiple Sclerosis

Safety and Efficacy of Natalizumab in Combination with Avonex in the Treatment of Multiple Sclerosis



Safety and Efficacy of Natalizumab in Combination with Avonex in the Treatment of Multiple Sclerosis

For Condition: Multiple Sclerosis
Status: No longer recruiting
Sponsor(s): Biogen Idec , Elan Pharmaceuticals
Synopsis: The purpose of this study is to determine if natalizumab in combination with AVONEX is safe and effective in delaying progression of individuals diagnosed with relapsing remitting MS.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Double-Blind, Placebo Control, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/50 Years
Genders: Both
Protocol Entry Criteria: Male and female subjects between 18 and 50 years of age who have a diagnosis of relapsing remitting multiple sclerosis and who have been treated with Avonex for at least 12 months prior to study entry.
Total Enrollment: 

Location and Contact Information:

University Hospital at Stony Brook
Stony Brook,  New York,  11794
United States
 

LSU Neurolgoy Clinic in New Orleans
New Orleans,  Louisiana,  70112
United States
 

University of Pittsburgh, Department of Neurology
Pittsburgh,  Pennsylvania,  15213
United States
 

Healthsouth Rehabilitation Hospital
Colorado Springs,  Colorado,  80910
United States
 

North Ridge NeuroScience Center
Ft. Lauderdale,  Florida,  33334
United States
 

Kaiser-Permanente Medical Center
Redwood City,  California,  94063
United States
 

Hopital Universitaire U.L.B. Erasme
Brussels,  ,  1780
Belgium
 

Universitaetsklinikum Giessen, Oberarzt Neurologie
Giessen,  ,  35390
Germany
 

Buffalo General Hospital, Department of Neurology
Buffalo,  New York,  14203
United States
 

Marietta Neurological Associates
Marietta,  Georgia,  30060
United States
 

Allegheny Singer Research Institute
Pittsburgh,  Pennsylvania,  15212
United States
 

Northwestern University, Department of Neurology
Chicago,  Illinois,  60611
United States
 

Griffin Hospital
Derby,  Connecticut,  06418
United States
 

St. Luke's Roosevelt Hospital, MS Research & Treatment Center
New York City,  New York,  10019
United States
 

Greenstein Neurology Associates & MS Institute
Philadelphia,  Pennsylvania,  19146
United States
 

Michigan Institute for Neurological Disorders
Farmington Hills,  Michigan,  48334
United States
 

Indiana University Medical Center
Indianapolis,  Indiana,  46202
United States
 

Maimonides Medical Center, Division of Neurology
Brooklyn,  New York,  11219
United States
 

MS Center at Carolinas Medical Center
Charlotte,  North Carolina,  28232-2861
United States
 

Noran Neurological Clinic
Minneapolis,  Minnesota,  55404
United States
 

Albany Medical Center
Albany,  New York,  12208
United States
 

UTSW Medical School
Dallas,  Texas,  75235-9036
United States
 

Providence Saint Vincent Medical Center
Portland,  Oregon,  97225
United States
 

University of Arkansas For Medical Sciences
Little Rock,  Arkansas,  72205
United States
 

Cleveland Clinic Foundation
Cleveland,  Ohio,  44195
United States
 

Henry Ford Hospital
Detroit,  Michigan,  48202-2608
United States
 

St. John's Mercy Medical Center
St. Louis,  Missouri,  63141
United States
 

New York Hospital - Cornell Medical Center
New York City,  New York,  10021
United States
 

Springfield Clinic Neuroscience Institute
Springfield,  Illinois,  62702
United States
 

Bernard W. Gimbel MS Center
Teaneck,  New Jersey,  07666
United States
 

Fachbereich Neurologie und Klinische Neurophysiologie
Wiesbaden,  ,  65191
Germany
 

Staten Island University Hospital
Staten Island,  New York,  10305
United States
 

University of Alabama-Birmingham, Department of Neurology
Birmingham,  Alabama,  35233
United States
 

Elisabeth Ziekenhuis
Sijsele,  ,  8340
Belgium
 

University of Massachusetts Memorial Medical Center
Worcester,  Massachusetts,  01655-0138
United States
 

Hospital of the University of Pennsylvania
Philadelphia,  Pennsylvania,  19104
United States
 

Mercy Hospital Outpatient Pharmacy
Des Moines,  Iowa,  50314
United States
 

Consultants in Neurology Northbrook
Northbrook,  Illinois,  60062
United States
 

Michigan State University MS Clinic
East Lansing,  Michigan,  48824
United States
 

Alexian Brothers Center for Clinical Research
Elk Grove Village,  Illinois,  60007
United States
 

Hadassah Hebrew Uni Hospital, Department of Neurology
Jerusalem,  , 
Israel
 

MS Center at UCSF
San Francisco,  California,  94117
United States
 

Virginia Mason Medical Center
Seattle,  Washington,  98111
United States
 

Neurologische Abteilung
Henningsdorf,  ,  16761
Germany
 

Universita di Genova, Clinica Neurologica
Genova,  ,  16132
Italy
 

MS Care Center
New York City,  New York,  10003
United States
 

Loyola Medical Center
Maywood,  Illinois,  60153
United States
 

Judisches Krankenhaus
Berlin,  ,  13347
Germany
 

Maine Neurology
Scarborough,  Maine,  04074-8926
United States
 

Geisinger Medical Center
Danville,  Pennsylvania,  17822
United States
 

Phoenix Neurological Associates, Ltd.
Phoenix,  Arizona,  85008
United States
 

University of California - Irvine
Irvine,  California,  92697
United States
 

Vanderbilt Medical Center
Nashville,  Tennessee,  37215
United States
 

Brigham and Women's Hospital
Boston,  Massachusetts,  02115
United States
 

University of Maryland Hospital, Department of Neurology
Baltimore,  Maryland,  21201
United States
 

SUNY Upstate Medical University
Syracuse,  New York,  13210
United States
 

University of Miami, Department of Neurology
Miami,  Florida,  33136
United States
 

University of Virginia Health Sciences
Charlottesville,  Virginia,  22908
United States
 

Upstate Clinical Research, LLC
Albany,  New York,  12205
United States
 

University of Colorado MS Center
Denver,  Colorado,  80262
United States
 

Hopital neurologique Pierre Werth
Lyon,  ,  69394
France
 

Baylor Methodist International MS Center
Houston,  Texas,  77030
United States
 

MS Research Center
Seattle,  Washington,  98195
United States
 

USC MS Comprehensive Care Center
Los Angeles,  California,  90033
United States
 

Wake Forest University School of Medicine, Department of Neurology
Winston Salem,  North Carolina,  27157
United States
 

Option Care Infusion
Dallas,  Texas,  75226
United States
 

Universitatsklinik fur Neurologie
Innsbruck,  ,  6020
Austria
 

University of Mississippi Medical Center
Jackson,  Mississippi,  39216-4505
United States
 

New York State Psychiatric Institution
New York City,  New York,  10032
United States
 

The Multiple Sclerosis Center of Atlanta
Atlanta,  Georgia,  30327
United States
 

Rush-Presbyterian St. Luke's Medical Center
Chicago,  Illinois,  60612
United States
 

Riverhills Neurology
Cincinnati,  Ohio,  45219
United States
 

Fletcher Allen Health Care
Burlington,  Vermont,  05401
United States
 

Strong Health Pharmacy Services
Rochester,  New York,  14642
United States
 

Asklepios Klinik Schildautal
Seesen/Harz,  ,  38723
Germany
 

George Washington University MS Center
Washington D.C.,  District of Columbia,  20037
United States
 

Sheba Medical Center, MS Center
Tel Hashomer,  ,  52621
Israel
 

Universitatsklinik fur Neurologie
Graz,  ,  8036
Austria
 

Central Texas Neurology
Round Rock,  Texas,  78681
United States
 

Hopital Pellegrin Tripode, Neurologie
Bordeaux,  ,  33076
France
 

Medizinische Hochschule Hannover, Neurologische Klinik
Hannover,  ,  30625
Germany
 

Maitland Neurology
Maitland,  Florida,  32751
United States
 

Neurological Associates, Inc.
Richmond,  Virginia,  23226
United States
 

St. Francis Hospital, Center for Neurological Disorders
Milwaukee,  Wisconsin,  53215
United States
 

University of Tennessee - Memphis
Memphis,  Tennessee,  38163
United States
 

Städtische Kliniken Osnabrück
Osnabrück,  ,  49076
Germany
 

Raleigh Neurology Associates
Raleigh,  North Carolina,  27607
United States
 

Georgetown Univesity Hospital, Research Pharmacy
Washington D.C.,  District of Columbia,  20007
United States
 


Additional Information:
Study ID Numbers:
  C-1802; 
Study Start Date: January 2002
Record last reviewed: January 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00030966

Other Multiple Sclerosis Studies:
1. A 48-Week (24-Week Baseline Followed by a 24-Week Treatment) Phase II Pilot Study of the Tolerability and Effect/Efficacy of Subcutaneously Administered Insulin-Like Growth Factor-1 (rhIGF) (CEP-151) in Multiple Sclerosis (MS) Patients

2. Zenapax to Treat Multiple Sclerosis

3. Combination Therapy with Avonex and BiMonthly High Dose Intravenous Methotrexate in Multiple Sclerosis

4. Diagnostic Study of Quantitative Imaging and Spectroscopy in Patients With Multiple Sclerosis

5. Safety and Efficacy of AVP-923 for Pseudobulbar Affect in Multiple Sclerosis Patients

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Safety and Efficacy of Natalizumab in Combination with Avonex in the Treatment of Multiple Sclerosis

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