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Resistance to Vitamin D or Parathyroid Hormone Clinical Trials Facts presented on Clinical Trials Search is not designed to be a substitute for certified medical advice, travels to or treatment with a real dr.. We aren't doctors. Always consult your mD on Resistance to Vitamin D or Parathyroid Hormone conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Resistance to Vitamin D or Parathyroid Hormone Clinical research trials and Resistance to Vitamin D or Parathyroid Hormone medical trials occur in many of places across the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally assess the effectiveness of new does drugs. The role of the studies / undertakings is to figure out certain human healthcare questions. Clinical trials are a popular means for doctors, government agencies, and private sector corporations to locate treatments for all forms of circumstances, including Resistance to Vitamin D or Parathyroid Hormone. Resistance to Vitamin D or Parathyroid Hormone Clinical Trials and other clinical trials permit volunteers to get medical treatment options before they are available to the masses. Most times the human subjects acquire treatment for free of charge, and sometimes they are paid for their time. Occasionally there is a cost for a Resistance to Vitamin D or Parathyroid Hormone clinical trial. Participants oftentimes recieve the finest healthcare available for their Resistance to Vitamin D or Parathyroid Hormone condition. Dangers are a reality, nonetheless, and might include extra or frequent physician calls, health hazards (potentially life-endangering), and/or the treatment being ineffectual. Trials are federally regulated with strict guidelines to protect clinical trials subjects.
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Home > "R" Clinical Trials Conditions > Resistance to Vitamin D or Parathyroid Hormone  Resistance to Vitamin D or Parathyroid Hormone
Resistance to Vitamin D or Parathyroid Hormone
For Condition: Hypocalcemia,Osteomalacia,Pseudohypoparathyroidism,Pseudopseudohypoparathyroidism,Rickets
Status: Recruiting
Sponsor(s): National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ,
Synopsis: Patients with confirmed or suspected conditions with a resistance to vitamin D or parathyroid hormone (PTH) will be admitted for diagnosis and treatment, and inclusion in other studies pertaining to similar conditions. This study will provide information about problems relating to calcium in the blood, urine, and bones. Patients in this study will undergo a general evaluation / check-up to give researchers an idea of each person's condition or disease. Patients will receive treatment based on their diagnosis and asked to provide specimen samples for further research studies.
Details: Patients with confirmed or suspected states with resistance to vitamin D or parathyroid hormone (PTH) will be admitted for diagnosis and treatment and for inclusion in other protocols. These states include hypocalcemia, rickets, osteomalacia, pseudohypoparathyroidism. Resistance to a factor is manifested by deficient bioeffect despite high levels of the factor in blood. Patients will be tested with multiple indices of mineral metabolism to establish the diagnosis and examine the spectrum of the underlying disorder. The principal therapies will be combinations of calcium, phosphate, and a vitamin D analog. Selected patients will have localization and surgery to remove a tumor that causes renal wasting of phosphate. Patients will also undergo research tests which may include skin biopsy or apheresis and will be considered for entry into other protocols.
Eligibility:
Study Type: Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: INCLUSION CRITERIA Patients of any age or sex with vitamin D resistance, rickets, osteomalacia, pseudohypoparathyroidism, pseudo-pseudohypoparathyroidism, or suspicion of these or related disorders based upon the appropriateness of their problem to ongoing investigations. Current investigations are focused primarily upon subjects with target tissue resistance to 1,25-dihydroxyvitamin D, pseudohypoparathyroidism, and pseudo-pseudohypoparathyroidism.
Total Enrollment: 9999
Location and Contact Information:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) *Recruiting*
Bethesda, Maryland, 20892
United States
Recruiting Patient and Public Liaison Office 1-800-411-1222
Additional Information:
Study ID Numbers: 890173; 89-DK-0173
Study Start Date: September 29, 1989
Record last reviewed: August 11, 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001242
Other Osteomalacia Studies:
1. Studies with Vitamin D
2. Resistance to Vitamin D or Parathyroid Hormone
Related Studies:
Other Osteomalacia Clinical Trials
Other Maryland Clinical Trials
Other Bethesda Clinical Trials
Resistance to Vitamin D or Parathyroid Hormone
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