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Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases Clinical Trials Resources presented on Clinical Trials Search is not meant to be a substitute for proven health advice, calls or treatment with a real medical. We aren't mDs. Always consult your doctor on Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases Clinical research trials and Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases healthcare trials take place in a lot of of localities throughout the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectiveness of new does drugs. The function of the studies / projects is to figure out specific human medical questions. Clinical trials are a popular means for doctors, government agencies, and private sector corporations to find cures for all varieties of conditions, like Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases. Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases Clinical Trials and other clinical trials allow volunteers to access health treatment options before they are available to the masses. Many times the subjects receive professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases clinical trial. Human subjects often obtain the finest healthcare possible for their Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases condition. Hazards are a reality, nevertheless, and might include additional or frequent dr. calls, health hazards (potentially life-jeopardizing), and/or the treatment being uneffective. Trials are federally regulated with stern guidelines to protect clinical trials patients.
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Home > "R" Clinical Trials Conditions > Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases  Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases
Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases
For Condition: brain metastases
Status: No longer recruiting
Sponsor(s): National Cancer Institute (NCI) , Radiation Therapy Oncology Group
Synopsis: RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. It is not yet known whether giving radiation therapy during surgery is more effective than standard radiation therapy in treating brain metastases. PURPOSE: Randomized phase III trial to compare the effectiveness of radiation therapy with or without radiosurgery in treating patients with brain metastases that cannot be removed during surgery.
Details: OBJECTIVES: I. Compare the overall survival of patients with one unresected brain metastasis treated with conventional whole brain radiotherapy (WBRT) with vs. without a stereotactic radiosurgery (SRS) boost. II. Compare sites of recurrence and cause of death in these patients treated with WBRT followed by SRS vs. WBRT alone. PROTOCOL OUTLINE: This is a randomized, multicenter study. Patients are stratified according to center and extracranial disease (yes or no). Patients are randomized to one of two treatment arms. Arm I: Patients receive fractionated external beam whole brain irradiation (WBRT) 5 days each week for 3 weeks. Both portals are treated during each radiotherapy session. Patients who still have a solitary lesion with a diameter no greater than 4.0 cm also receive stereotactic radiosurgery within 7 days of completing WBRT. Arm II: Patients receive WBRT only. Patients are followed every 3 months for 1 year, then every 4 months for 2 years, and then annually. PROJECTED ACCRUAL: A total of 262 patients will be accrued over 2.5-3.75 years for this study. The study may close early if interim analysis after 33% and 67% of patients have been followed for 6 months produces significant results. After 6/14/99 an additional 46 patients with a solitary brain metastasis only will be accrued.
Eligibility:
Study Type: Interventional, Treatment
Minimum Age/Maximum Age: 18 Years/
Genders:
Protocol Entry Criteria: PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- - No more than 1 unresected or subtotally resected brain metastasis lesion from histologically confirmed systemic malignancy - Eligible only if surgical resection refused by patient or resection deemed inappropriate by patient's physician - 1 intraparenchymal metastasis clearly defined on contrast enhanced MRI - Maximum diameter of lesion no greater than 4.0 cm - No leukemia or lymphoma - Extracranial sites of primary metastatic disease allowed if no clinical or radiographic evidence of progression within 1 month prior to entry - No metastasis to brainstem, midbrain, pons, or medulla - No leptomeningeal metastasis by MRI or CSF evaluation - No metastasis within 10 mm of optic nerves and chiasm (area must be excluded from high dose stereotactic radiosurgery boost field) --Prior/Concurrent Therapy-- - Biologic therapy: Not specified - Chemotherapy: No concurrent chemotherapy for systemic cancer - Endocrine therapy: Concurrent hormonal therapy, including tamoxifen, allowed - Radiotherapy: No prior cranial radiotherapy - Surgery: Prior subtotal resection allowed - Other: No other concurrent treatment for brain metastasis until recurrence --Patient Characteristics-- - Age: 18 and over - Performance status: 70-100% Karnofsky - Hematopoietic: Absolute neutrophil count at least 1,000/mm3; Platelet count at least 50,000/mm3; Hemoglobin at least 8 g/dL - Hepatic: Not specified - Renal: Not specified - Other: Neurologic status 0-2; No major medical or psychiatric contraindication to protocol entry; Fertile patients must use effective contraception
Total Enrollment:
Location and Contact Information:
Overall Study Official:
DavidAndrews, Study Chair, Radiation Therapy Oncology Group
Mount Diablo Medical Center
Concord, California, 94524-4110
United States
Radiation Oncology Center - Sacramento
Sacramento, California, 95816
United States
Wilford Hall - 59th Medical Wing
Lackland Air Force Base, Texas, 78236-5300
United States
Southern Wisconsin Radiotherapy Center
Madison, Wisconsin, 53713
United States
Veterans Affairs Medical Center - Indianapolis (Roudebush)
Indianapolis, Indiana, 46202
United States
Cancer Center, University of Virginia HSC
Charlottesville, Virginia, 22908
United States
Western Baptist Hospital
Paducah, Kentucky, 42001
United States
Dixie Regional Medical Center
St. George, Utah, 84770
United States
Urology Associates - Mobile AL
Mobile, Alabama, 36640
United States
Deaconess Medical Center
Spokane, Washington, 99210-0248
United States
CCOP - Ann Arbor Regional
Ann Arbor, Michigan, 48106
United States
Providence Cancer Therapy Center
Anchorage, Alaska, 99508
United States
Methodist Medical Center of Illinois
Peoria, Illinois, 61636
United States
York Hospital
York, Pennsylvania, 17315
United States
St. Joseph's Hospital
Milwaukee, Wisconsin, 53210
United States
Northeastern Ontario Regional Cancer Centre, Sudbury
Sudbury, Ontario, P3E 5J1
Canada
East Texas Medical Center - Cancer Institute
Tyler, Texas, 75701
United States
Medical College of Wisconsin
Milwaukee, Wisconsin, 53226
United States
Loyola University Medical Center
Maywood, Illinois, 60153
United States
Cancer Research for the Ozarks
Springfield, Missouri, 65807
United States
Arizona Cancer Center
Tucson, Arizona, 85724
United States
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, 48109-0752
United States
Alabama Oncology, LLC
Montgomery, Alabama, 36106-2801
United States
MBCCOP - Gulf Coast
Mobile, Alabama, 36652
United States
Vanderbilt-Ingram Cancer Center
Nashville, Tennessee, 37232-6838
United States
University of Wisconsin Comprehensive Cancer Center
Madison, Wisconsin, 53792
United States
Newfoundland Cancer Treatment and Research Foundation
St. Johns, Newfoundland and Labrador, A1B 3V6
Canada
University of Colorado Cancer Center
Denver, Colorado, 80262
United States
University of Pittsburgh Cancer Institute
Pittsburgh, Pennsylvania, 15213
United States
Joe Arrington Cancer Research and Treatment Center
Lubbock, Texas, 79410-1894
United States
Beckman Research Institute, City of Hope
Los Angeles, California, 91010
United States
O'Connor Hospital
San Jose, California, 95128
United States
Medical Center/John B. Amos Community Cancer Center
Columbus, Georgia, 31902
United States
CCOP - Kalamazoo
Kalamazoo, Michigan, 49007-3731
United States
Saint Agnes Cancer Center
Fresno, California, 93720
United States
Sylvester Cancer Center, University of Miami
Miami, Florida, 33136
United States
University Hospitals of Cleveland
Cleveland, Ohio, 44106
United States
Sparrow Regional Cancer Center
Lansing, Michigan, 48909
United States
Newark Beth Israel Medical Center
Newark, New Jersey, 07112
United States
Fox Chase Cancer Center at Virtua Memorial Hospital Burlington County
Mount Holly, New Jersey, 08060
United States
Albert Einstein Cancer Center
Philadelphia, Pennsylvania, 19141
United States
Whittingham Cancer Center
Norwalk, Connecticut, 06856
United States
St. John's Medical Center
Anderson, Indiana, 46016
United States
William Beaumont Hospital
Royal Oak, Michigan, 48073
United States
Hahnemann University Hospital
Philadelphia, Pennsylvania, 19102-1192
United States
NYU School of Medicine's Kaplan Comprehensive Cancer Center
New York City, New York, 10016
United States
Mercy Catholic Medical Center, Mercy Fitzgerald Divison
Darby, Pennsylvania, 19023
United States
Roger Williams Medical Center/BUSM
Providence, Rhode Island, 02908-4735
United States
Bridgeport Hospital
Bridgeport, Connecticut, 06610
United States
South Jersey Hospital - Millville
Millville, New Jersey, 08332
United States
University of Rochester Cancer Center
Rochester, New York, 14642
United States
Kimmel Cancer Center of Thomas Jefferson University - Philadelphia
Philadelphia, Pennsylvania, 19107
United States
Naval Medical Center, Portsmouth
Portsmouth, Virginia, 23708-2197
United States
Albert B. Chandler Medical Center, University of Kentucky
Lexington, Kentucky, 40536-0084
United States
Peninsula Regional Medical Center
Salisbury, Maryland, 21801
United States
St. Mary's Medical Center
Saginaw, Michigan, 48601
United States
Barbara Ann Karmanos Cancer Institute
Detroit, Michigan, 48201
United States
Sarasota Radiation and Medical Oncology Center
Sarasota, Florida, 34233
United States
CCOP - Central Illinois
Decatur, Illinois, 62526
United States
St. John Medical Center
Tulsa, Oklahoma, 74104
United States
Maine Medical Center
Portland, Maine, 04102
United States
CCOP - Columbia River Program
Portland, Oregon, 97213
United States
Nova Scotia Cancer Centre
Halifax, Nova Scotia, B3H 1V7
Canada
CCOP - MainLine Health
Wynnewood, Pennsylvania, 19096
United States
Rapid City Regional Hospital
Rapid City, South Dakota, 57709
United States
Jackson-Madison County General Hospital
Jackson, Tennessee, 38301
United States
Schiffler Cancer Center
Wheeling, West Virginia, 26003
United States
Comprehensive Cancer Institute of Huntsville
Huntsville, Alabama, 35801
United States
Radiation Therapy Associates - Fort Myers
Ft. Myers, Florida, 33901
United States
Elliot Regional Cancer Center
Manchester, New Hampshire, 03103
United States
McGill University Department of Oncology
Montreal, Quebec, H2W 1S6
Canada
Veterans Affairs Medical Center - Lexington
Lexington, Kentucky, 40511-1093
United States
Tom Baker Cancer Center - Calgary
Calgary, Alberta, T2N 4N2
Canada
Nebraska Health System
Omaha, Nebraska, 68198-7400
United States
University of Chicago Cancer Research Center
Chicago, Illinois, 60637
United States
CCOP - Cancer Research for the Ozarks
Springfield, Missouri, 65807
United States
Finger Lakes Radiation Oncology, P.C.
Clifton Springs, New York, 14432
United States
Tallahassee Memorial Healthcare
Tallahassee, Florida, 32308
United States
Mayo Clinic Cancer Center
Rochester, Minnesota, 55905
United States
Christ Hospital
Cincinnati, Ohio, 45219
United States
RMH Regional Canter Center
Harrisonburg, Virginia, 22801
United States
Cancer Care Ontario-Hamilton Regional Cancer Centre
Hamilton, Ontario, L8V 5C2
Canada
Anne Arundel Oncology Center
Annapolis, Maryland, 21401
United States
Gundersen Lutheran Medical Foundation
La Crosse, Wisconsin, 54601
United States
Ottawa Regional Cancer Centre - General Campus
Ottawa, Ontario, K1H 1C4
Canada
Hurley Medical Center
Flint, Michigan, 48503
United States
University of Texas Medical Branch
Galveston, Texas, 77555-0209
United States
CCOP - Upstate Carolina
Spartanburg, South Carolina, 29303
United States
Kingston Regional Cancer Centre
Kingston, Ontario, K7L 5P9
Canada
CCOP - Ochsner
New Orleans, Louisiana, 70121
United States
St. Francis Medical Center
Trenton, New Jersey, 08629
United States
Vermont Cancer Center
Burlington, Vermont, 05401-3498
United States
Cross Cancer Institute
Edmonton, Alberta, T6G 1Z2
Canada
Yakima Valley Memorial Hospital
Yakima, Washington, 98902
United States
Provena St. Joseph Hospital- Regional Cancer Care Center
Elgin, Illinois, 60123
United States
Veterans Affairs Medical Center - Philadelphia
Philadelphia, Pennsylvania, 19104
United States
Atlantic City Medical Center
Pomona, New Jersey, 08240
United States
Cooper Cancer Institute
Camden, New Jersey, 08103
United States
CCOP - North Shore University Hospital
Manhasset, New York, 11030
United States
Cancer Care Center
Pomona, California, 91767
United States
St. Louis University Health Sciences Center
St. Louis, Missouri, 63110-0250
United States
Mary Bird Perkins Cancer Center
Baton Rouge, Louisiana, 70809
United States
North Mississippi Medical Center/Cancer Center
Tupelo, Mississippi, 38801
United States
Columbia Hospital
Milwaukee, Wisconsin, 53211
United States
Louisville Radiation Oncology
Louisville, Kentucky, 40215
United States
Merle M. Mahr Cancer Center
Madisonville, Kentucky, 42431
United States
Northeast Medical Center
Concord, North Carolina, 28025
United States
Champlain Valley Physicians Hospital Medical Center
Plattsburgh, New York, 12901
United States
Radiation Medical Group, Inc.
San Diego, California, 92101-1492
United States
Sinai Hospital of Baltimore
Baltimore, Maryland, 21225
United States
Lykes Center for Radiation Therapy
Clearwater, Florida, 33757-0210
United States
Arthur G. James Cancer Hospital - Ohio State University
Columbus, Ohio, 43210
United States
InterCommunity Cancer Center at Rome
Rome, Georgia, 30161
United States
Radiation Oncology Affiliates of Maryland, P.A.
Baltimore, Maryland, 21237
United States
BC Cancer Agency
Vancouver, British Columbia, V5Z 4E6
Canada
Clarion Health Partners Inc.
Indianapolis, Indiana, 46206-1367
United States
John F. Kennedy Medical Center
Edison, New Jersey, 08818
United States
CCOP - Southeast Cancer Control Consortium
Winston Salem, North Carolina, 27104-4241
United States
Methodist Cancer Center - Omaha
Omaha, Nebraska, 68114
United States
Veterans Affairs Medical Center - Milwaukee (Zablocki)
Milwaukee, Wisconsin, 53295
United States
Herbert Irving Comprehensive Cancer Center
New York City, New York, 10032
United States
CCOP - Montana Cancer Consortium
Billings, Montana, 59101
United States
University of Utah Health Sciences Center
Salt Lake City, Utah, 84132
United States
University of Pennsylvania Cancer Center
Philadelphia, Pennsylvania, 19104
United States
Saskatoon Cancer Centre
Saskatoon, Saskatchewan, S7N 4H4
Canada
Community Medical Center
Toms River, New Jersey, 08755
United States
Memorial Hospital Cancer Center
Colorado Springs, Colorado, 80909
United States
Veterans Affairs Medical Center - Boston (Jamaica Plain)
Jamaica Plain, Massachusetts, 02130
United States
Virginia Mason Medical Center
Seattle, Washington, 98111
United States
Wendt Regional Cancer Center of Finley Hospital
Dubuque, Iowa, 52001
United States
Florida Radiation Oncology Group
Orange Park, Florida, 32073
United States
Tulane University School of Medicine
New Orleans, Louisiana, 70112
United States
Ingalls Memorial Hospital
Harvey, Illinois, 60426
United States
Doctor Leon Richard Oncology Centre
Moncton, New Brunswick, E1C 8X3
Canada
Harbor Hospital Center
Baltimore, Maryland, 21225
United States
Lehigh Valley Hospital
Allentown, Pennsylvania, 18103
United States
Northwestern Memorial Hospital
Chicago, Illinois, 60611
United States
McLaren Regional Cancer Center
Flint, Michigan, 48432
United States
Norris Cotton Cancer Center
Lebanon, New Hampshire, 03756
United States
CCOP - Metro-Minnesota
St. Louis Park, Minnesota, 55416
United States
Huntsville Hospital System
Huntsville, Alabama, 35801
United States
CCOP - Southern Nevada Cancer Research Foundation
Las Vegas, Nevada, 89106
United States
Saint John Regional Hospital
Saint John, New Brunswick, E2L 4L2
Canada
Bay Medical Center
Panama City, Florida, 32401
United States
CCOP - Dayton
Kettering, Ohio, 45429
United States
Baptist Hospital of Miami
Miami, Florida, 33176-2197
United States
Harrington Cancer Center
Amarillo, Texas, 79106
United States
James Graham Brown Cancer Center
Louisville, Kentucky, 40202
United States
CCOP - Toledo Community Hospital Oncology Program
Toledo, Ohio, 43623-3456
United States
Comprehensive Cancer Center of Wake Forest University Baptist Medical Center
Winston Salem, North Carolina, 27157-1082
United States
Martha Jefferson Hospital
Charlottesville, Virginia, 22901
United States
MD Anderson Cancer Center Orlando
Orlando, Florida, 32806
United States
Trinitas Hospital - Jersey Street Campus
Elizabeth, New Jersey, 07201
United States
Cape Cod Hospital
Hyannis, Massachusetts, 02601
United States
Meritcare Roger Maris Cancer Center
Fargo, North Dakota, 58122
United States
East Carolina University School of Medicine
Greenville, North Carolina, 27858-4354
United States
University of Tennessee, Memphis Cancer Center
Memphis, Tennessee, 38103
United States
Community Hospitals of Indianapolis - Regional Cancer Center
Indianapolis, Indiana, 46219
United States
University of Alabama Comprehensive Cancer Center
Birmingham, Alabama, 35294
United States
Ireland Cancer Center
Cleveland, Ohio, 44106-5065
United States
St. Anthony Hospital
Oklahoma City, Oklahoma, 73101
United States
St. Vincent Hospital
Green Bay, Wisconsin, 54307-3508
United States
Health First Holmes Regional Medical Center
Melbourne, Florida, 32901
United States
St. Joseph's Radiation Oncology Center
South Bend, Indiana, 46617
United States
New York Methodist Hospital
Brooklyn, New York, 11215-3609
United States
Johns Hopkins Oncology Center
Baltimore, Maryland, 21231
United States
Memorial Sloan-Kettering Cancer Center
New York City, New York, 10021
United States
H. Lee Moffitt Cancer Center and Research Institute
Tampa, Florida, 33612
United States
CCOP - Bay Area Tumor Institute
Oakland, California, 94609-3305
United States
Vassar Brothers Hospital
Poughkeepsie, New York, 12601
United States
Marshfield Clinic
Marshfield, Wisconsin, 54449
United States
Gulf Coast Cancer Treatment Center
Panama City, Florida, 32405-4587
United States
Centre Universitaire de Sante de l'Estrie - Site Fleurimont
Fleurimont, Quebec, J1H 5N4
Canada
Penn State Geisinger Cancer Center
Hershey, Pennsylvania, 17033
United States
MidMichigan Medical Center - Midland
Midland, Michigan, 48670
United States
Reading Hospital and Medical Center
Reading, Pennsylvania, 19612-6052
United States
Mobile Infirmary Medical Center
Mobile, Alabama, 36640-0460
United States
Mallinckrodt Institute of Radiology
St. Louis, Missouri, 63110
United States
Veterans Affairs Medical Center - East Orange
East Orange, New Jersey, 07018-1095
United States
Ball Memorial Hospital
Muncie, Indiana, 47303-3499
United States
UCSF Cancer Center and Cancer Research Institute
San Francisco, California, 94115-0128
United States
CCOP - Christiana Care Health Services
Wilmington, Delaware, 19899
United States
Marquette General Hospital
Marquette, Michigan, 49855
United States
Geisinger Medical Center
Danville, Pennsylvania, 17822-2001
United States
Greater Baltimore Medical Center and Cancer Center
Baltimore, Maryland, 21204
United States
Catawba Memorial Hospital
Hickory, North Carolina, 28601
United States
Medical University of South Carolina
Charleston, South Carolina, 29425-0721
United States
Mercy Hospital Cancer Center - Scranton
Scranton, Pennsylvania, 18501
United States
CCOP - Mount Sinai Medical Center
Miami, Florida, 33140
United States
Sutter Health Western Division Cancer Research Group
Greenbrae, California, 94904
United States
Akron City Hospital
Akron, Ohio, 44309
United States
CCOP - Columbus
Columbus, Ohio, 43206
United States
State University of New York Health Science Center at Brooklyn
Brooklyn, New York, 11203
United States
Southeastern Wisconsin Regional Cancer Center
Racine, Wisconsin, 53405
United States
Albert Einstein Comprehensive Cancer Center
Bronx, New York, 10461
United States
Saint Joseph Medical Center
Albuquerque, New Mexico, 87102
United States
MBCCOP - LSU Medical Center
New Orleans, Louisiana, 70112
United States
Akron General Medical Center
Akron, Ohio, 44302
United States
Virginia Baptist Hospital
Lynchburg, Virginia, 24503
United States
Walter Reed Army Medical Center
Washington D.C., District of Columbia, 20307-5000
United States
Waukesha Memorial Hospital
Waukesha, Wisconsin, 53188
United States
CCOP - Atlanta Regional
Atlanta, Georgia, 30342-1701
United States
Princess Margaret Hospital
Toronto, Ontario, M5G 2M9
Canada
University of Texas - MD Anderson Cancer Center
Houston, Texas, 77030-4009
United States
Northwestern Ontario Regional Cancer Centre, Thunder Bay
Thunder Bay, Ontario, P7A 7T1
Canada
California Cancer Center
Fresno, California, 93720
United States
Halifax Medical Center
Daytona Beach, Florida, 32114
United States
Cancer Care Ontario-London Regional Cancer Centre
London, Ontario, N6A 4L6
Canada
Toronto Sunnybrook Regional Cancer Centre
Toronto, Ontario, M4N 3M5
Canada
Northwest Community Hospital
Arlington Heights, Illinois, 60005
United States
Lutheran General Cancer Care Center
Park Ridge, Illinois, 60068
United States
Cancer Institute of New Jersey
New Brunswick, New Jersey, 08901
United States
Veterans Affairs Medical Center - Long Beach
Long Beach, California, 90822
United States
CCOP - Kansas City
Kansas City, Missouri, 64131
United States
University of California San Diego Cancer Center
La Jolla, California, 92093-0658
United States
Green Mountain Oncology Group
Rutland, Vermont, 05701
United States
Lineberger Comprehensive Cancer Center, UNC
Chapel Hill, North Carolina, 27599-7295
United States
Julie and Ben Rogers Cancer Institute
Beaumont, Texas, 77701
United States
Baptist Regional Cancer Center - Knoxville
Knoxville, Tennessee, 37901
United States
Loma Linda University Medical Center
Loma Linda, California, 92354
United States
Stanford University
Stanford, California, 94305
United States
Henry Ford Hospital
Detroit, Michigan, 48202
United States
Monmouth Medical Center
Long Branch, New Jersey, 07740
United States
Fox Chase Cancer Center
Philadelphia, Pennsylvania, 19111
United States
CCOP - Greenville
Greenville, South Carolina, 29615
United States
CCOP - Baptist Cancer Institute
Memphis, Tennessee, 38117
United States
CCOP - Southwestern Vermont Regional Cancer Center
Bennington, Vermont, 05201
United States
Veterans Affairs Medical Center - Miami
Miami, Florida, 33125
United States
Bayshore Medical Center
Pasadena, Texas, 77504
United States
UNIMED Medical Center
Minot, North Dakota, 58701
United States
Kaiser Permanente Medical Center - Los Angeles
Los Angeles, California, 90027
United States
St. Luke's Medical Center
Milwaukee, Wisconsin, 53215
United States
USC/Norris Comprehensive Cancer Center
Los Angeles, California, 90033-0800
United States
Western Pennsylvania Hospital
Pittsburgh, Pennsylvania, 15224
United States
Community Memorial Hospital
Menomonee Falls, Wisconsin, 53051
United States
Beth Israel Medical Center
New York City, New York, 10003
United States
Glendale Memorial Hospital and Health Center
Glendale, California, 91204
United States
St. Luke's Hospital Regional Cancer Center
Bethlehem, Pennsylvania, 18015
United States
Swedish Cancer Institute
Seattle, Washington, 98104
United States
Memorial Hospital of South Bend
South Bend, Indiana, 46601
United States
Mercy Hospital of Pittsburgh
Pittsburgh, Pennsylvania, 15219
United States
Wilkes Barre General Hospital
Wilkes Barre, Pennsylvania, 18764
United States
University of Florida Health Science Center
Gainesville, Florida, 32610-0296
United States
Cancer Center of Albany Medical Center
Albany, New York, 12208
United States
Associated Radiologists, P.A.
Warren, New Jersey, 07059
United States
Jonsson Comprehensive Cancer Center, UCLA
Los Angeles, California, 90095-1781
United States
University of Iowa Hospitals and Clinics
Iowa City, Iowa, 52242
United States
Ellis Fischel Cancer Center - Columbia
Columbia, Missouri, 65203
United States
Radiation Oncology Associates of West Alabama
Tuscallosa, Alabama, 35401
United States
New York Medical College
Valhalla, New York, 10595
United States
Bayfront Medical Center
Saint Petersburg, Florida, 33701
United States
West Florida Cancer Institute - Pensacola
Pensacola, Florida, 32514
United States
Delaware County Memorial Hospital
Drexel Hill, Pennsylvania, 19026
United States
Emory University Hospital - Atlanta
Atlanta, Georgia, 30322
United States
Romagosa Radiation Oncology Center
Lafayette, Louisiana, 70501
United States
LDS Hospital
Salt Lake City, Utah, 84143
United States
Roswell Park Cancer Institute
Buffalo, New York, 14263-0001
United States
CCOP - Santa Rosa Memorial Hospital
Santa Rosa, California, 95403
United States
Additional Information:
Study ID Numbers: CDR0000064522; RTOG-9508
Study Start Date: January 1996
Record last reviewed: April 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00002708
Other Brain Metastases Studies:
1. Radiosurgery With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain Metastases
2. Carmustine Implants in Treating Patients With Brain Metastases
3. Temozolomide and Radiation Therapy in Treating Patients With Stage IV Malignant Melanoma With Measurable and Unresectable Cancer Involving the Central Nervous System
4. Melatonin and Radiation Therapy in Treating Patients With Brain Metastases
5. Temozolomide in Treating Patients With Brain Metastases
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Radiation Therapy With or Without Radiosurgery in Treating Patients With Brain Metastases
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