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Radiation Therapy After Surgery in Treating Patients With Phyllodes Tumor of the Breast Clinical Trials Facts presented on Clinical Trials Search isn't designed to be a substitute for proven healthcare advice, calls or treatment by using a genuine medical doctor. We aren't mDs. Always confer with your doctor on Radiation Therapy After Surgery in Treating Patients With Phyllodes Tumor of the Breast conditions. Clinical Trials Search.org is a website devoted to listing clinical research studies in human subjects. Radiation Therapy After Surgery in Treating Patients With Phyllodes Tumor of the Breast Clinical research trials and Radiation Therapy After Surgery in Treating Patients With Phyllodes Tumor of the Breast healthcare trials occur in a lot of of places across the United States. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally assess the effectivity of new does drugs. The role of the studies / undertakings is to solve specific human healthcare questions. Clinical trials are a popular way for doctors, government agencies, and private sector companies to find treatments for all kinds of conditions, including Radiation Therapy After Surgery in Treating Patients With Phyllodes Tumor of the Breast. Radiation Therapy After Surgery in Treating Patients With Phyllodes Tumor of the Breast Clinical Trials and other clinical trials allow for volunteers to access health treatment choices before they are available to the general public. Many times the test subjects get treatment for without cost, and sometimes they are compensated for their time. Occasionally there is a cost for a Radiation Therapy After Surgery in Treating Patients With Phyllodes Tumor of the Breast clinical trial. Test subjects typically receive the most effective healthcare possible for their Radiation Therapy After Surgery in Treating Patients With Phyllodes Tumor of the Breast condition. Risks are a reality, nonetheless, and could include extra or frequent dr. calls, health hazards (perhaps life-jeopardizing), and/or the treatment being ineffective. Trials are federally regulated with rigid guidelines to protect clinical trials subjects.
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Home > "R" Clinical Trials Conditions > Radiation Therapy After Surgery in Treating Patients With Phyllodes Tumor of the Breast  Radiation Therapy After Surgery in Treating Patients With Phyllodes Tumor of the Breast
Radiation Therapy After Surgery in Treating Patients With Phyllodes Tumor of the Breast
For Condition: Phyllodes Tumor,breast cancer in situ,recurrent breast cancer
Status: Recruiting
Sponsor(s): Norris Cotton Cancer Center ,
Synopsis: RATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells. Radiation therapy following surgery may be effective in treating patients with phyllodes tumor of the breast. PURPOSE: Phase II trial to study the effectiveness of radiation therapy after surgery in treating patients with phyllodes tumor of the breast.
Details: OBJECTIVES: - Determine the local recurrence rate in patients with phyllodes tumors of the breast previously treated with local excision with negative margins and are now treated with adjuvant radiotherapy. - Determine the survival rate in patients treated with this regimen. OUTLINE: Within 12 weeks after prior local excision or breast reexcision, patients undergo adjuvant radiotherapy 5 days a week for a total of 28 treatments. Patients are followed every 6 months for 10 years. PROJECTED ACCRUAL: A total of 50 patients will be accrued for this study within approximately 6-7 years.
Eligibility:
Study Type: Interventional, Treatment
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: DISEASE CHARACTERISTICS: - Histologically proven phyllodes tumors of the breast with borderline or malignant grade, defined as 1 of the following: - Borderline, defined as 5-9 mitoses/10 high power fields (HPF), pushing or infiltrating margins, 2+ atypia - Malignant, defined as 10 or more mitoses/10 HPF, predominantly infiltrating margins, usually 3+ atypia with occasional 2+ atypia - Must have been excised with breast-conserving resection - No positive margins - Local recurrence of a previously excised phyllodes tumor allowed if the recurrence is in the area of the prior excision - No prior breast carcinoma or ductal carcinoma in situ in the ipsilateral breast - Hormone receptor status: - Not specified PATIENT CHARACTERISTICS: Age: - 18 and over Sex: - Female Menopausal status: - Not specified Performance status: - Not specified Life expectancy: - Not specified Hematopoietic: - Not specified Hepatic: - Not specified Renal: - Not specified Other: - Not pregnant - Negative pregnancy test - Fertile patients must use effective contraception PRIOR CONCURRENT THERAPY: Biologic therapy - Not specified Chemotherapy - Not specified Endocrine therapy - Not specified Radiotherapy - No prior radiotherapy to the ipsilateral breast Surgery - See Disease Characteristics
Total Enrollment:
Location and Contact Information:
Overall Study Official:
RichardBarth, Study Chair, Norris Cotton Cancer Center
Norris Cotton Cancer Center at Dartmouth Medical School *Recruiting*
Lebanon, New Hampshire, 03756-0002
United States
Recruiting Richard Barth 603-650-7903
Additional Information:
Study ID Numbers: CDR0000066410; DMS-9801,DMS-12752,NCI-V98-1442
Study Start Date:
Record last reviewed: April 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00003404
Other Phyllodes Tumor Studies:
1. Radiation Therapy After Surgery in Treating Patients With Phyllodes Tumor of the Breast
Related Studies:
Other Phyllodes Tumor Clinical Trials
Other New Hampshire Clinical Trials
Other Lebanon Clinical Trials
Radiation Therapy After Surgery in Treating Patients With Phyllodes Tumor of the Breast
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