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Quality of Life in Patients with Chronic Ischemic Heart Disease Clinical Trials Facts presented on Clinical Trials Search is not designed to be a substitute for certified medical advice, travels to or treatment with a real dr.. We aren't doctors. Always consult your mD on Quality of Life in Patients with Chronic Ischemic Heart Disease conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Quality of Life in Patients with Chronic Ischemic Heart Disease Clinical research trials and Quality of Life in Patients with Chronic Ischemic Heart Disease medical trials occur in many of places across the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally assess the effectiveness of new does drugs. The role of the studies / undertakings is to figure out certain human healthcare questions. Clinical trials are a popular means for doctors, government agencies, and private sector corporations to locate treatments for all forms of circumstances, including Quality of Life in Patients with Chronic Ischemic Heart Disease. Quality of Life in Patients with Chronic Ischemic Heart Disease Clinical Trials and other clinical trials permit volunteers to get medical treatment options before they are available to the masses. Most times the human subjects acquire treatment for free of charge, and sometimes they are paid for their time. Occasionally there is a cost for a Quality of Life in Patients with Chronic Ischemic Heart Disease clinical trial. Participants oftentimes recieve the finest healthcare available for their Quality of Life in Patients with Chronic Ischemic Heart Disease condition. Dangers are a reality, nonetheless, and might include extra or frequent physician calls, health hazards (potentially life-endangering), and/or the treatment being ineffectual. Trials are federally regulated with strict guidelines to protect clinical trials subjects.
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Home > "Q" Clinical Trials Conditions > Quality of Life in Patients with Chronic Ischemic Heart Disease  Quality of Life in Patients with Chronic Ischemic Heart Disease
Quality of Life in Patients with Chronic Ischemic Heart Disease
For Condition: Myocardial Ischemia,Ischemic Heart Disease
Status: Completed
Sponsor(s): Warren G Magnuson Clinical Center (CC) ,
Synopsis: This study will examine the health-related quality of life in patients being treated for chronic heart disease. Patients 18 years or older with chronic ischemic heart disease and left ventricular dysfunction enrolled in protocols in the National Heart Lung and Blood Institute's Cardiology Branch may participate in this study. Participants will complete five questionnaires at 3 separate times during the study-once during hospitalization at the NIH Clinical Center and again at home 6 months and 1 year later. The questionnaires, described below, require a total of about 30 minutes to complete. 1. Demographic Information Sheet -General information such as age, marital status, employment, education, and history of cardiac medical procedures. 2. General Health Survey -Patient's self-assessment, on a rating scale, of physical and emotional well being. Questions are related to the ability to perform work and daily living activities, mood and state of mind, limitations on social activities, energy level, pain level, general quality of life, etc. 3. Heart Disease Survey - Patient's self-assessment, on a rating scale, of the level of physical, social, emotional and functional well being related to his or her heart condition. Questions concern fatigue level, emotional outlook, social well being, etc. 4. Angina Survey - Information on the frequency of chest pain, chest tightness, or angina. 5. Symptom Distress Survey - Patient's ranking of the degree of symptom distress from chest discomfort, difficulty breathing, heart rate irregularities, wheezing and coughing. All information provided in the questionnaires will be kept confidential. Upon request, patients will be sent a summary of the study results when the study is completed.
Details: A majority of the research in patients with chronic ischemic heart disease and left ventricular dysfunction deals with increasing patient survival rates and years. Very little research has focused on patients' perceptions of living with this chronic debilitating disease. The purpose of this naturalistic, prospective study is to assess the Health Related Quality of Life (HRQOL), anginal symptoms and symptom distress experienced by patients with chronic ischemic heart disease and left ventricular dysfunction. The relationship between underlying cardiac condition, anginal symptoms, symptom distress and HRQOL will be examined. The trend in HRQOL across time versus treatment group will be evaluated. The question, does HRQOL, anginal frequency and symptom distress at baseline predict mortality and cardiac related hospitalization during the year following assessment will also be addressed. Patients who are enrolled in protocols in the Cardiology Branch of the National Heart Lung and Blood Institute (NHLBI) and diagnosed with chronic ischemic heart disease and left ventricular dysfunction will be asked to participate in this HRQOL study. Patients will complete measures of HRQOL (Medical Outcomes Short Form 36 Survey; Minnesota Living with Heart Failure Questionnaire) and symptom measures (anginal frequency subscale of the Seattle Angina Questionnaire; cardiopulmonary subscale of the Heart Transplant Symptom Checklist). Underlying cardiac condition will be assessed using exercise thallium imaging parameters (METS and perfusion defects) and positron emission tomography (PET) imaging parameter (viability). A sample size of 90 subjects is desired for this study. Data will be analyzed using multivariate statistics. It is expected that this study will provide new information regarding how patients with ischemic heart disease and left ventricular function feel their chronic illness and its corresponding treatment(s) affects their HRQOL.
Eligibility:
Study Type: Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: Known coronary artery disease. Left ventricular ejection fraction less that or equal to 45%. Signed informed consent. Must be able to read written English.
Total Enrollment: 105
Location and Contact Information:
Warren G. Magnuson Clinical Center (CC)
Bethesda, Maryland, 20892
United States
Additional Information:
Study ID Numbers: 000131; 00-CC-0131
Study Start Date: May 20, 2000
Record last reviewed: May 2, 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00005671
Other Myocardial Ischemia Studies:
1. Quality of Life in Patients with Chronic Ischemic Heart Disease
2. Outcomes following myocardial revascularization: on and off cardiopulmonary bypass
3. Warfarin versus Aspirin in Reduced Cardiac Ejection Fraction (WARCEF) Trial
Related Studies:
Other Myocardial Ischemia Clinical Trials
Other Maryland Clinical Trials
Other Bethesda Clinical Trials
Quality of Life in Patients with Chronic Ischemic Heart Disease
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