|
Prospective Study of HIV Infection in Hemophiliacs Clinical Trials Resources presented on Clinical Trials Search is not meant to be a substitute for proven health advice, calls or treatment with a real medical. We aren't mDs. Always consult your doctor on Prospective Study of HIV Infection in Hemophiliacs conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Prospective Study of HIV Infection in Hemophiliacs Clinical research trials and Prospective Study of HIV Infection in Hemophiliacs healthcare trials take place in a lot of of localities throughout the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectiveness of new does drugs. The function of the studies / projects is to figure out specific human medical questions. Clinical trials are a popular means for doctors, government agencies, and private sector corporations to find cures for all varieties of conditions, like Prospective Study of HIV Infection in Hemophiliacs. Prospective Study of HIV Infection in Hemophiliacs Clinical Trials and other clinical trials allow volunteers to access health treatment options before they are available to the masses. Many times the subjects receive professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a Prospective Study of HIV Infection in Hemophiliacs clinical trial. Human subjects often obtain the finest healthcare possible for their Prospective Study of HIV Infection in Hemophiliacs condition. Hazards are a reality, nevertheless, and might include additional or frequent dr. calls, health hazards (potentially life-jeopardizing), and/or the treatment being uneffective. Trials are federally regulated with stern guidelines to protect clinical trials patients.
|
|
|
|
|
|
|
Home > "P" Clinical Trials Conditions > Prospective Study of HIV Infection in Hemophiliacs  Prospective Study of HIV Infection in Hemophiliacs
Prospective Study of HIV Infection in Hemophiliacs
For Condition: HIV Infections,Blood Disease,Hepatitis, Viral, Human,Cytomegalovirus Infections,Blood Transfusion,Acquired Immunodeficiency Syndrome,Hemophilia A
Status: Completed
Sponsor(s): National Heart, Lung, and Blood Institute (NHLBI) ,
Synopsis: To examine mechanisms of individual differences in the progression of HIV infection in hemophiliacs.
Details: BACKGROUND: In the late 1980s, hemophiliacs were transfused with a variety of blood products, including large amounts of cryoprecipitate. In comparison to other cohorts, hemophiliacs are CMV(-), resulting in a comparison group for the study of this virus as a potential cofactor. In contrast, non A, non-B hepatitis is common in comparison to other cohorts, and preliminary data prior to 1990 suggested that this chronic disease predisposes to more rapid progression of HIV infection. DESIGN NARRATIVE: Disease-free survival rates were determined in HIV-infected hemophiliacs. The effects of co-factors such as intensive transfusion, concomitant cytomegalovirus or chronic NANB hepatitis infection were ascertained. Host-virus interaction was assessed through the use of plasma cultures, specific antibody titers, and markers of immune changes detected by flow cytometry and immune function assays. The immunology of asymptomatic stable infection was investigated. The safety of volunteer donor blood products was determined in seronegative patients exposed to over 50,000 donors yearly and the risk of sexual transmission of HIV to spouses of seropostive patients was monitored.
Eligibility:
Study Type: Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Male
Protocol Entry Criteria: No eligibility criteria
Total Enrollment:
Location and Contact Information:
Additional Information:
Study ID Numbers: 3012;
Study Start Date: July 1990
Record last reviewed: November 2001
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00005309
Other Hepatitis, Viral, Human Studies:
1. A Compassionate Use Study of Tenofovir Disoproxil Fumarate as Treatment for HIV Infection
2. Effects of home visits on medication adherence in children and youth with HIV
3. Safety and Effectiveness of Giving Lamisil to HIV-Positive Subjects With Thrush Who Have Not Responded to Fluconazole Treatment
4. The Safety and Effectiveness of Interferon Alfa-2B Plus Didanosine in Patients with Kaposi's Sarcoma
5. Effects of Immunization with HIV-1 Immunogen Plus Anti-HIV Treatment Interruption on the Levels of HIV
Related Studies:
Other Hepatitis, Viral, Human Clinical Trials
Other Clinical Trials
Other Clinical Trials
Prospective Study of HIV Infection in Hemophiliacs
|
|
|
|
|
|
|
|
