|
Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia Clinical Trials Information presented on Clinical Trials Search is not designed to be a substitute for certified medical advice, trips or professional assistance with a real medical doctor. We aren't docs. Always confer with your doctor about Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia Clinical research trials and Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia health trials happen in many of cities across the US. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally measure the effectualness of new does drugs. The intention of the studies / projects is to figure out particular human healthcare questions. Clinical trials are a popular manner for doctors, government agencies, and private sector corporations to detect cures for all forms of circumstances, like Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia. Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia Clinical Trials and other clinical trials allow for volunteers to undergo medical treatment options before they are available to the general public. Most times the subjects get treatment for free of charge, and occasionally they are paid for their time. Occasionally there is a cost for a Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia clinical trial. Subjects frequently get the best healthcare possible for their Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia condition. Hazards are a reality, however, and could include more or frequent mD visits, health risks (possibly life-jeopardizing), and/or the treatment being ineffectual. Trials are federally regulated with exacting guidelines to protect clinical trials patients.
|
|
|
|
|
|
|
Home > "P" Clinical Trials Conditions > Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia  Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia
Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia
For Condition: Chronic Lymphocytic Leukemia,CLL
Status: Recruiting
Sponsor(s): Genta ,
Synopsis: This non-randomized study will test the safety and effectiveness of Genasense in patients with CLL.
Details: This study is a two-part phase I-II study. Part 1 will determine the MTD of Genasense in patients with CLL. This dose will then be tested in a non-randomized, multi-center, Phase II sequential clinical trial of Genasense used alone for treatment of patients with advanced CLL. Pharmacokinetics of Genasense and kinetics of Bcl-2 down regulation and re-expression in CLL cells will be followed in selected patients.
Eligibility:
Study Type: Interventional, Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: -Any age -Must have received at least one chemotherapy regimen that included fludarabine -Measurable disease -At least 3 weeks since biological therapy or radiation therapy for chronic lymphocytic leukemia -No previous stem cell transplantation -At least 3 weeks since surgery
Total Enrollment: 49
Location and Contact Information:
Long Island Jewish Medical Center *Recruiting*
New Hyde Park, New York,
United States
Recruiting Patient Recruiter 888-322-2264
MD Anderson Cancer Center *Recruiting*
Houston, Texas,
United States
Recruiting Patient Recruiter 888-322-2264
San Antonio Cancer Institute *Recruiting*
San Antonio, Texas,
United States
Recruiting Patient Recruiter 888-322-2264
US Oncology *Recruiting*
Dallas, Texas,
United States
Recruiting Patient Recruiter 888-322-2264
Ohio State University James Cancer Center *Not yet recruiting*
Columbus, Ohio,
United States
Not yet recruiting Patient Recruiter 888-322-2264
Additional Information:
Study ID Numbers: GL208; G3139,Bcl-2 Antisense
Study Start Date: January 2001
Record last reviewed: January 2001
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00021749
Other Chronic Lymphocytic Leukemia Studies:
1. Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia
Related Studies:
Other Chronic Lymphocytic Leukemia Clinical Trials
Other Texas Clinical Trials
Other Houston Clinical Trials
Phase I/II Study of Genasense in Patients With Chronic Lymphocytic Leukemia
|
|
|
|
|
|
|
|
