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Phase I Safety Study of anti-HIV Immune Serum Globulin (Human)



Phase I Safety Study of anti-HIV Immune Serum Globulin (Human)

For Condition: HIV Infections
Status: Completed
Sponsor(s): Abbott Laboratories ,
Synopsis: To investigate the potential benefit of providing passive immunity with hyperimmune anti-HIV human serum.
Details:
Eligibility:
Study Type:  Interventional, Treatment, Safety Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria Patients must have: - Proof of HIV infection. - Diagnosis of asymptomatic HIV infection or early AIDS related complex (ARC) with no zidovudine (AZT) or other anti-HIV therapy. OR a diagnosis of AIDS and = or > 3 months of AZT therapy. Exclusion Criteria Co-existing Condition: Patients with the following conditions or symptoms are excluded: - HIV-induced neurological disease. - IgA negative. Concurrent Medication: Excluded: - Immunomodulating agents. - Steroids. - Interferons. Patients with the following are excluded: - Active substance abuse. - Use of immunomodulating drugs such as steroids or interferons. - HIV-induced neurological disease. - IgA negative. Required with a diagnosis of AIDS: - = or > 3 months of zidovudine (AZT) therapy. Active substance abuse.
Total Enrollment: 12

Location and Contact Information:

Univ of Minnesota
Minneapolis,  Minnesota,  55455
United States
 


Additional Information:
Study ID Numbers:  060A;  0001-008
Study Start Date: 
Record last reviewed: February 1990
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00002036

Other Hiv Infections Studies:
1. The Safety and Effectiveness of SPC3 in HIV-1 Infected Patients

2. Tuberculosis in HIV Infected Patients in Uganda

3. A Study of Peer Education to Prevent HIV Transmission among Injection Drug Users and Their HIV Risk Contacts

4. Therapeutic Vaccination Followed by Treatment Interruption in HIV Infected Patients

5. Comparison of GW433908/Ritonavir to Nelfinavir When Used with Abacavir and Lamivudine in Patients That Have Not Taken Antiretroviral Drugs

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