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Pharmacokinetics and Bioavailability of Liquid vs Tablet Buprenorphine - 6



Pharmacokinetics and Bioavailability of Liquid vs Tablet Buprenorphine - 6

For Condition: Opioid-Related Disorders
Status: No longer recruiting
Sponsor(s): National Institute on Drug Abuse (NIDA) ,
Synopsis: To evaluate the steady-state pharmacokinetics and bioavailability of buprenorphine sublingual tablets vs. sublingual solution.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Double-Blind, Uncontrolled, Crossover Assignment
Minimum Age/Maximum Age: 21 Years/50 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: M/F ages 21-50. Meet DSM-IV criteria for opioid dependence. Agree to conditions of the study and sign informed consent. Exclusion Criteria: Psychiatric disorder that requires medication therapy. History of seizures. Pregnant and/or nuring women. Dependence on ETOH or benzodiazepines or other sedative/hypnotics. Acute hepatitis. Other medical condtions that deem participation to be unsafe.
Total Enrollment: 1

Location and Contact Information:

Overall Study Official:
WalterLing,  Principal Investigator,  Friends Research Institute

Friends Research Institute
Los Angeles,  California,  90025
United States
 


Additional Information:
Study ID Numbers:
  NIDA-3-0010-6; 
Study Start Date: August 1996
Record last reviewed: August 1996
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00000341

Other Opioid-Related Disorders Studies:
1. Effects of Behavioral Contingencies on Effects of Nitrous Oxide - 12

2. Buprenorphine/Naloxone Treatment for Opioid Dependence-Experiment II-1 - 4

3. Alternate-Day Buprenorphine Administration. Phase IV - 5

4. Role of Instructions in Nitrous Oxide Effects and Choice - 10

5. PK0496 Pharmacokinetics of Buprenorphine - 10

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