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OSI-774 (Tarceva) in Treating Patients with Stage III or Stage IV Non-Small Cell Lung Cancer Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for qualified medical advice, visits or professional assistance by using a real mD. We are not docs. Always confer with your physician about OSI-774 (Tarceva) in Treating Patients with Stage III or Stage IV Non-Small Cell Lung Cancer conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. OSI-774 (Tarceva) in Treating Patients with Stage III or Stage IV Non-Small Cell Lung Cancer Clinical research trials and OSI-774 (Tarceva) in Treating Patients with Stage III or Stage IV Non-Small Cell Lung Cancer health trials occur in many of cities throughout the US. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally evaluate the effectivity of new does drugs. The intent of the studies / undertakings is to resolve particular human health questions. Clinical trials are a popular way for physicians, government agencies, and private sector companies to detect remedies for all sorts of conditions, including OSI-774 (Tarceva) in Treating Patients with Stage III or Stage IV Non-Small Cell Lung Cancer. OSI-774 (Tarceva) in Treating Patients with Stage III or Stage IV Non-Small Cell Lung Cancer Clinical Trials and other clinical trials permit volunteers to obtain healthcare treatment alternatives before they are available to the masses. Most times the participants undergo professional assistance for without cost, and occasionally they are compensated for their time. Occasionally there is a cost for a OSI-774 (Tarceva) in Treating Patients with Stage III or Stage IV Non-Small Cell Lung Cancer clinical trial. Test subjects typically receive the most expert healthcare available for their OSI-774 (Tarceva) in Treating Patients with Stage III or Stage IV Non-Small Cell Lung Cancer condition. Dangers are a reality, however, and may include more or frequent mD visits, healthcare dangers (perhaps life-endangering), and/or the treatment being ineffectual. Trials are federally regulated with rigid guidelines to protect clinical trials patients.
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Home > "O" Clinical Trials Conditions > OSI-774 (Tarceva) in Treating Patients with Stage III or Stage IV Non-Small Cell Lung Cancer OSI-774 (Tarceva) in Treating Patients with Stage III or Stage IV Non-Small Cell Lung Cancer
OSI-774 (Tarceva) in Treating Patients with Stage III or Stage IV Non-Small Cell Lung Cancer
For Condition: Carcinoma, Non-Small-Cell Lung
Status: Completed
Sponsor(s): OSI Pharmaceuticals , National Cancer Institute of Canada
Synopsis: The purpose of this study is to determine if OSI-774 will improve overall survival of patients with incurable stage IIIB/IV non-small cell lung cancer compared to standard of care. OSI-774 is a new type of drug under evaluation called an epidermal growth factor receptor (EGFR). OSI-774 is an investigational drug that has not yet been approved by the U.S. Food and Drug Administration (FDA).
Details:
Eligibility:
Study Type: Interventional, Treatment, Randomized, Double-Blind, Placebo Control, Parallel Assignment, Efficacy Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: - Clinical diagnosis of stage IIIB or IV non-small cell lung cancer. - Must have evidence of disease (clinical or radiological). - Have failed 1 but no more than 2 prior chemotherapy regimens, have recovered from any side effects and have not had any chemotherapy for at least 21 days. - If the patient has had surgery, the surgery was at least 2 weeks ago. - Patients whose cancer has spread to their brain or central nervous system are eligible, providing that they have been on stable dose of steroids for at least 4 weeks and are free of symptoms. - If the patient received radiation therapy, treatment was at least 4 weeks ago.
Total Enrollment: 700
Location and Contact Information:
Overall Study Official:
FrancesShepherd, Study Chair,
Newcastle Mater Misericordiae Hospital
Waratah, New South Wales, 2289
Australia
University of Chicago Medical Center
Chicago, Illinois, 60637
United States
Hospital Sao Lucas da PUCRS
Porto Alegre, RS CEP, 90610-000
Brazil
Asklepios Fachkiniken
Gauting, , 82131
Germany
Hamilton Regional Cancer Centre
Hamilton, Ontario, L9V 5C2
Canada
National Cancer Centre - Singapore
Singapore, , 169610
Singapore
CancerCare Manitoba (CCMB)
Winnipeg, Manitoba, R3E 0V9
Canada
Eastern Cape Oncology Centre
Port Elizabeth, , 6000
South Africa
The Royal Victoria Hospital
Barrie, Ontario, L4M 6M2
Canada
Oncotherapy Dept, National Hospital
Bloemfontein, , 9301
South Africa
Lund University Hospital
Lund, ,
Sweden
Southlake Regional Health Centre
Newmarket, Ontario, L3Y 2P9
Canada
Lungenklinik Hermer
Hermer, , 58675
Germany
Prince of Wales Hospital
Randwick, New South Wales, 2031
Australia
Kingston Regional Cancer Centre
Kingston, Ontario, K7L 5P9
Canada
Instituto Oncologico Angel Roffo
Capital Federal, , CP1417
Argentina
Rabin Medical Center Golda Campus
Petach-Tiqva, , 49372
Israel
Chiangmai University
Chiangmai, , 50002
Thailand
Instituto do Cancer Arnaldo Vieira de Carvalho
Sao Paulo, SP, 01224-010
Brazil
Toronto-Sunnybrook Reg.Canc.Center
Toronto, Ontario, M4N 3M5
Canada
Kaplan Medical Center
Rehovot, ,
Israel
Instituto Nacional de Cancerologia
Mexico City, CP, 14000
Mexico
Rabin Medical Center Beilinson Campus
Petach-Tiqva, , 49100
Israel
Zentrum fur pheulmologie und Thoraxchirurgie
Grosshansdorf, , 22927
Germany
Sotiria Hospital
ATHENS, , 115 27
Greece
Hospital Central Sur de Alta Especialidad, PEMEX
Mexico City, ,
Mexico
Hospital Britanico
Buenos Aires, , 1280
Argentina
Toronto East General Hospital
Toronto, Ontario, M4C 3E7
Canada
Sahlgrenska University Hospital
Lund, ,
Sweden
Greenlane Hospital - New Zealand
Auckland 3, ,
New Zealand
Peter MacCallum Cancer Institute
Victoria, , 3002
Australia
Centro Estatal de Cancerologia de Durango
Durango, ,
Mexico
Queen Mary Hospital
Hong Kong, ,
China
Northeastern Ontario Regional Cancer Centre
Sudbury, Ontario, P3E 5J1
Canada
Allan Blair Cancer Centre
Regina, Saskatchewan, S4T 7T1
Canada
Mary Potter Oncology Centre
Pretoria, ,
South Africa
Thoraxklinik Heidelberg
Heidelberg, , 69126
Germany
QEII Health Sciences Centre
Halifax, Nova Scotia, B3H 2Y9
Canada
Hopital Laval
Ste Foy, Quebec, G1V 4G5
Canada
Assaf Harofeh Medical Center
Zerifin, , 70300
Israel
Durban Oncology Centre
Westbridge, Durban, 4091
South Africa
Pamela Youde Nethersole Easter Hospital
Hong Kong, ,
China
Austin & Repatriation Medical Centre
Victoria, , 3084
Australia
Irmandade Santa Casa de Miseicordia de Porto
Porto Alegre, RS CEP, 90020-090
Brazil
Johannesburg Hospital
PARKTOWN, , 2193
South Africa
Sandton Oncology Centre
Parklands, , 2121
South Africa
Cancer Centre for the Southern Interior
Kelowna, British Columbia, V1Y 5L3
Canada
Sourasky Medical Center Oncology Institute
Tel Aviv, , 64239
Israel
University of Washington
Seattle, Washington, 98109
United States
Oncology Institute Bucharest
Bucharest, ,
Romania
Escola Paulista de Medicina
Sao Paulo, SP CEP, 040039-032
Brazil
Faculdade de Medicina do ABC
Santo Andre, SP CEP, 09060-650
Brazil
Lungenklinik Heckeshorn
Berlin, , 14109
Germany
Canberra Hospital- Australia
Woden, Australian Capital Territory, 2605
Australia
Credit Valley Hospital
Missisauga, Ontario, L5M 2N1
Canada
Wellington Hospital
Riddiford Street, Wellington,
New Zealand
Hospital Italiano
Capital Federal, ,
Argentina
Princess Margaret Hospital
Toronto, Ontario, M5G 2M9
Canada
Die Wilgers Hospital
Lynnwood, Pretoria,
South Africa
Royal Adelaide Hospital
South Australia, , 5000
Australia
BCCA - Vancouver Island
Victoria, British Columbia, V8R 6V5
Canada
Oncology Institute Ion Chiricuta
Cluj Napoca, , 3400
Romania
Hospital Vera Cruz S/A
Belo Horizonte, MG CEP, 30190-130
Brazil
Dr.H. Bliss Murphy Cancer Centre
St. John's, Newfoundland and Labrador, A1B 3V6
Canada
RAMBAM Medical Center
Haifa, ,
Israel
Ottawa Regional Cancer Centre
Ottawa, Ontario, K1H 1C4
Canada
National University Hospital
Singapore, , 119074
Singapore
Nucleo de Oncologia da Bahia
Salvador, Bahia, 40170-070
Brazil
Hopital Du Sacre - Coeur De Montreal
Montreal, Quebec, H4J 1C5
Canada
Clinical County Hospital
Sibiu, , 2400
Romania
Group Health Centre
Sault St. Marie, Ontario, P6A 2C4
Canada
Humbar River Regional Hospital
Weston, Ontario, M9N 1N8
Canada
McGill University
Montreal, Quebec, H2W 1S6
Canada
Rosebank Clinic Oncology Unit
Rosebank, ,
South Africa
Spitalul Universitar
Iasi, , 6600
Romania
Hotel Dieu Health Sciences Hospital
St. Catherines, Ontario, L2R 5K3
Canada
The Royal Melbourne Hospital
Parkville, Victoria, 3050
Australia
Mount Sinai Hospital
Toronto, Ontario, M5G 1X5
Canada
Tom Baker Cancer Centre
Calgary, Alberta, T2N 4N2
Canada
Institution: Clinica Las Condes
Santiago, ,
Chile
Sheba Medical Center Oncology Day Care
Tel Hashomer, , 52621
Israel
Centro Medico Confidence
Buenos Aires, CP, 1642
Argentina
Peterborough Regional Health Centre
Peterborough, Ontario, K9H 7B6
Canada
Hospital Interzonal de Agudos Evita
Buenos Aires, , B1824
Argentina
Haemek Medical Center
Afula, , 18101
Israel
Southern Medical Day Care Center
Wollongong, New South Wales, 2500
Australia
Hopital Notre-Dame du CHUM
Montreal, Quebec, H2L 4M1
Canada
Western Hospital
Footscray, Victoria, 3011
Australia
Instituto Alexander fleming
Buenos Aires, , C1426ANZ
Argentina
Div. of Med Onc. The National Cancer Institute of Thailand
Bangkok, , 10400
Thailand
Cross Cancer Institute
Edmonton, Alberta, T6G 1Z2
Canada
University of Pretoria
Pretoria, ,
South Africa
Pramongkutklao Hospital
Phayathai, Bangkok, 10400
Thailand
Instituto Nacional de Cancerologia
Rio de Janeiro, CEP, 20230-130
Brazil
Instituto do Cancer do Ceara
Fortaleza, CEP, 60430-230
Brazil
Hospital Churruca Visca
Buenos Aires, , C1427
Argentina
Sir Charles Gairdner Hospital
Nedlands, Western Australia, 6009
Australia
Additional Information:
Study ID Numbers: OSI-774-BR.21;
Study Start Date: October 2001
Record last reviewed: February 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00036647
Other Carcinoma, Non-Small-Cell Lung Studies:
1. Study of DN101 and Taxotere in patients with advanced non-small cell lung cancer
2. ALIMTA (pemetrexed) Plus Gemcitabine (Gemzar) for Patients with Locally Advanced or Metastatic Non-Small Cell Lung Cancer who have not had Previous Chemotherapy.
3. Study of Temozolomide in the Treatment of Brain Metastasis from Non-small-cell Lung Cancer
4. Phase II Trial of a 96-Hour Continuous Infusion of Paclitaxel Followed by Cisplatin for Patients with Stage III/IV and Relapsed NSCLC
5. OSI-774 (Tarceva) in Treating Patients with Stage III or Stage IV Non-Small Cell Lung Cancer
Related Studies:
Other Carcinoma, Non-Small-Cell Lung Clinical Trials
Other Clinical Trials
Other Gauting Clinical Trials
OSI-774 (Tarceva) in Treating Patients with Stage III or Stage IV Non-Small Cell Lung Cancer
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