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NF2 Natural History Consortium



NF2 Natural History Consortium

For Condition: Meningioma,Schwannoma, Vestibular,Neurofibromatosis 2
Status: Recruiting
Sponsor(s): House Ear Institute ,
Synopsis: OBJECTIVES: I. Define the growth rates and clinical course of NF2-related tumors in patients with neurofibromatosis type 2. Associate growth rate with physical function.
Details: PROTOCOL OUTLINE: Data on the clinical course and growth rate of NF2-related tumors in patients with neurofibromatosis 2. Patients are evaluated each year on a cranial and a spinal MRI, eye tests, hearing tests, quality of life, neurological tests, and physical functioning.
Eligibility:
Study Type:
  Observational, Natural History, Longitudinal
Minimum Age/Maximum Age: 5 Years/
Genders: Both
Protocol Entry Criteria: PROTOCOL ENTRY CRITERIA: --Disease Characteristics-- - Diagnosed with neurofibromatosis 2 on or after 01/01/93 - Must meet one of the following conditions: Bilateral vestibular schwannoma OR Family history of neurofibromatosis 2 (first degree family relative) AND Unilateral vestibular schwannoma at under 30 years OR Any 2 of the following: Meningioma Glioma Schwannoma Juvenile posterior subcapsular lenticular opacity/juvenile cortical cataract - No plans to treat vestibular schwannoma in next 12 months --Prior/Concurrent Therapy-- - Not specified --Patient Characteristics-- - Age: 5 and over
Total Enrollment: 100

Location and Contact Information:

Overall Study Official:
WilliamSlattery,  Study Chair,  House Ear Institute

University of Texas Health Science Center - Houston *Recruiting*
Houston,  Texas,  77225
United States
Recruiting Joseph  Chang 713-792-4875

Ohio State University *Recruiting*
Columbus,  Ohio,  43210
United States
Recruiting D.  Welling 614-292-2424

House Ear Institute *Recruiting*
Los Angeles,  California,  90057-9927
United States
Recruiting William  Slattery 213-483-9930

Klinikum Nord Ochsenzoll *Recruiting*
Hamburg,  ,  22419
Germany
Recruiting Victor  Mautner 49-40-5271-2872

Royal Victorian Eye and Ear Infirmary *Recruiting*
Melbourne,  , 
Australia
Recruiting Robert  Briggs 03 9929 8666

Massachusetts General Hospital *Recruiting*
Boston,  Massachusetts,  02114-2617
United States
Recruiting Mia  MacCollin 617-726-5724

Mount Sinai Medical Center, NY *Recruiting*
New York City,  New York,  10029
United States
Recruiting William  Carroll 212-241-4142


Additional Information:
Study ID Numbers:
  199/14226;  HEI-NF2,HEI-DAMD17-01-1-0710
Study Start Date: January 2002
Record last reviewed: October 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00004483

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