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Naltrexone Treatment for Alcoholism Clinical Trials Facts presented on Clinical Trials Search isn't designed to be a substitute for proven healthcare advice, calls or treatment using a real mD. We aren't mDs. Always confer with your physician on Naltrexone Treatment for Alcoholism conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Naltrexone Treatment for Alcoholism Clinical research trials and Naltrexone Treatment for Alcoholism healthcare trials happen in a lot of of localities across the United States of America. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally measure the potency of new drugs. The aim of the studies / undertakings is to answer particular human medical questions. Clinical trials are a popular manner for doctors, government agencies, and private sector corporations to discover remedies for all kinds of circumstances, such as Naltrexone Treatment for Alcoholism. Naltrexone Treatment for Alcoholism Clinical Trials and other clinical trials allow volunteers to get healthcare treatment alternatives before they are available to the general public. Most times the participants receive treatment for without cost, and occasionally they are paid for their time. Sometimes there is a cost for a Naltrexone Treatment for Alcoholism clinical trial. Human subjects often receive the most effective healthcare possible for their Naltrexone Treatment for Alcoholism condition. Risks are a reality, nonetheless, and may include more or frequent dr. calls, healthcare hazards (perhaps life-threatening), and/or the treatment being ineffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.
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Home > "N" Clinical Trials Conditions > Naltrexone Treatment for Alcoholism  Naltrexone Treatment for Alcoholism
Naltrexone Treatment for Alcoholism
For Condition: Alcoholism
Status: Completed
Sponsor(s): National Institute on Alcohol Abuse and Alcoholism (NIAAA) ,
Synopsis: This study will evaluate the effectiveness of the medication naltrexone (Revia) for treating alcoholism. Individuals will be inpatients for a 2 week period and provide assessments of their alcohol withdrawal symptoms, craving, and mood. Following hospital discharge, individuals will be assigned randomly to receive naltrexone daily, naltrexone twice a day or a placebo. This part of the study will last 12 weeks, with regular measurements of drinking level, craving and mood. Assessments will be conducted 6 and 12 months after the beginning of the study.
Details:
Eligibility:
Study Type: Interventional, Treatment, Randomized, Placebo Control, Efficacy Study
Minimum Age/Maximum Age: 30 Years/55 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Meets criteria for alcohol dependence. - Committed to alcohol abstinence as a treatment goal. - Individuals will be required to identify two family members or close friends who are knowledgeable about their location, drinking behavior, and psychosocial status. Exclusion Criteria: - Meets criteria for any other psychoactive substance use disorder (excluding nicotine and caffeine). - Meets criteria for a major psychiatric disorder and are in need of or currently undergoing pharmacotherapy. - Females who are pregnant, lactating, or not using a reliable method of contraception. - Currently experiencing a serious medical condition that would place them at risk or interfere with study participation. - Experiencing acute hepatitis or liver failure or whose liver function test is more than 3 times normal. - Have a history of severe allergies, multiple adverse drug reactions or known allergy to naltrexone. - Vocabulary below the 5th grade reading level. - Abnormal MRI scan. - HIV infection due to the neurological sequelae. - Significant central nervous system diseases. - Seizure disorder or history of closed head trauma. - Neuroendocrine disorders. - Treatment with opiates within the last six months.
Total Enrollment: 192
Location and Contact Information:
Johns Hopkins Hospital
Baltimore, Maryland, 21205
United States
Additional Information:
Study ID Numbers: NIAAAMCC11855;
Study Start Date:
Record last reviewed: March 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00000438
Other Alcoholism Studies:
1. Treatment for Alcoholism and Post-Traumatic Stress Disorder (naltrexone)
2. Acamprosate Treatment: Mechanisms of Action
3. Timing of Smoking Intervention in Alcohol Treatment (nicotine patch)
4. Combination Nicotine Replacement for Alcoholic Smokers
5. COMBINE (acamprosate/naltrexone)
Related Studies:
Other Alcoholism Clinical Trials
Other Maryland Clinical Trials
Other Baltimore Clinical Trials
Naltrexone Treatment for Alcoholism
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