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Multicenter Trial of Prednisone in Alzheimer's Disease



Multicenter Trial of Prednisone in Alzheimer's Disease

For Condition: Alzheimer Disease
Status: Completed
Sponsor(s): National Institute on Aging (NIA) ,
Synopsis: This is a randomized placebo controlled, double blind study. Patients who meet eligibility criteria and decide to participate in the study will be randomly assigned to receive either drug treatment or a placebo. Neither the patients nor the participating investigators will know who is receiving the drugs and who is receiving the placebo. Participation involves 15 outpatient clinic visits over a 68 week period. Patients take study medication at varying doses (the maximum dose is 20 mg daily), along with calcium and vitamin supplements.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Double-Blind, Placebo Control
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Patients with Alzheimer's disease who are in stable medical condition Exclusion Criteria: - Patients with diabetes or severe osteoporosis
Total Enrollment: 

Location and Contact Information:

Overall Study Official:
LeonThal,  Principal Investigator,  University of California, San Diego

University of Minnesota
Minneapolis,  Minnesota,  55455
United States
 

Indiana University Alzheimer's Center
Indianapolis,  Indiana,  46202
United States
 

Mount Sinai Medical Center
New York City,  New York,  10029
United States
 

Washington University
St. Louis,  Missouri,  63110
United States
 

University of Pittsburgh
Pittsburgh,  Pennsylvania,  15213
United States
 

University of California, San Diego
San Diego,  California,  92093-0949
United States
 

Johns Hopkins University
Baltimore,  Maryland,  21224
United States
 

University of Southern California
Los Angeles,  California,  90033
United States
 

Columbia Presbyterian Medical Center
New York City,  New York,  11032
United States
 

University of Kansas Medical Center
Kansas City,  Kansas,  66160
United States
 

University of Texas
Dallas,  Texas,  75235-9070
United States
 

University of Alabama, Birmingham
Birmingham,  Alabama,  35294-0017
United States
 

University of Rochester
Rochester,  New York,  14620
United States
 

Vanderbilt University Medical Center
Nashville,  Tennessee,  37212-8646
United States
 

University of Miami
Miami,  Florida,  33140
United States
 

Mayo Clinic Jacksonville
Jacksonville,  Florida,  32225
United States
 

Burke Medical Research Institute
White Plains,  New York,  10605
United States
 

New York University Medical Center
New York City,  New York,  10016
United States
 

University of South Florida
Tampa,  Florida,  33162
United States
 


Additional Information:
Study ID Numbers:
  IA0002;  3U01AG10483-08S2
Study Start Date: 
Record last reviewed: November 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00000178

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3. Bathing persons with Alzheimer's disease aT Home (The BATH Study)

4. The Safety and Efficacy of an Investigational Drug in Delaying the Progression of Alzheimer's Disease

5. Evaluation Of Three Doses of NS 2330 in Patients with Mild to Moderate Dementia of the Alzheimer’s Type

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