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Maturational Changes in Cardiac Structures -- Blood Pressure Relationship -- SCOR in Hypertension Clinical Trials References presented on Clinical Trials Search isn't meant to be a substitute for proven healthcare advice, trips or professional assistance using a genuine physician. We are not docs. Always confer with your physician about Maturational Changes in Cardiac Structures -- Blood Pressure Relationship -- SCOR in Hypertension conditions. Clinical Trials Search.org is a site devoted to listing clinical research studies in human subjects. Maturational Changes in Cardiac Structures -- Blood Pressure Relationship -- SCOR in Hypertension Clinical research trials and Maturational Changes in Cardiac Structures -- Blood Pressure Relationship -- SCOR in Hypertension healthcare trials happen in hundreds of localities throughout the United States of America. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials usually evaluate the potency of new drugs. The propose of the studies / projects is to answer particular human health questions. Clinical trials are a popular way for mDs, government agencies, and private sector companies to detect cures for all sorts of conditions, such as Maturational Changes in Cardiac Structures -- Blood Pressure Relationship -- SCOR in Hypertension. Maturational Changes in Cardiac Structures -- Blood Pressure Relationship -- SCOR in Hypertension Clinical Trials and other clinical trials allow volunteers to acquire healthcare treatment choices before they are available to the general public. Some times the subjects recieve professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a Maturational Changes in Cardiac Structures -- Blood Pressure Relationship -- SCOR in Hypertension clinical trial. Subjects frequently obtain the most expert healthcare possible for their Maturational Changes in Cardiac Structures -- Blood Pressure Relationship -- SCOR in Hypertension condition. Risks are a reality, nevertheless, and can include more or frequent doctor trips, medical risks (possibly life-threatening), and/or the treatment being uneffective. Trials are federally governed with stern guidelines to protect clinical trials patients.
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Home > "M" Clinical Trials Conditions > Maturational Changes in Cardiac Structures -- Blood Pressure Relationship -- SCOR in Hypertension Maturational Changes in Cardiac Structures -- Blood Pressure Relationship -- SCOR in Hypertension
Maturational Changes in Cardiac Structures -- Blood Pressure Relationship -- SCOR in Hypertension
For Condition: Cardiovascular Diseases,Heart Diseases,Hypertension
Status: Completed
Sponsor(s): National Heart, Lung, and Blood Institute (NHLBI) ,
Synopsis: To examine a school-based population of children for maturational changes in blood pressure and cardiac structures.
Details: BACKGROUND: Although excessive left ventricular mass has been viewed as an adaptation to increased blood pressure, it can precede the rise in blood pressure in hypertensive models. Excessive growth of the heart may reflect additional factors contributing to eventual level of blood pressure. In children, rapid heart growth may be predictive of subsequent high childhood blood pressure level and greater incidence of cardiovascular disease in adult relatives. These studies had the potential of defining maturational changes in known risk factors which might help predict future hypertensive disease. The study was a subproject within a Specialized Center of Research (SCOR) in Hypertension. The Request for Applications for the SCOR was released in October, 1988. DESIGN NARRATIVE: A total of 124 prepubertal males and females were followed longitudinally for five years. Yearly examinations defined the stages of sexual maturation. On four occasions each year, subjects were studied for resting and ambulatory blood pressure, echocardiography, anthropometry and activity assessment. Once yearly, each subject had blood drawn for hormone analyses and whole blood viscosity estimate. From these data, growth velocities of the heart and rate of change of blood pressure were determined. These parameters were analyzed to determine if rapid growth of the heart preceded or followed the rise in blood pressure observed during puberty and body size and composition, sexual maturation and hormone changes, and sympathetic activity. The study was a subproject within a SCOR in Hypertension. Approximately 7 percent of total dollars were awarded for this subproject.
Eligibility:
Study Type: Observational, Natural History, Longitudinal
Minimum Age/Maximum Age: /
Genders: Male
Protocol Entry Criteria: No eligibility criteria
Total Enrollment:
Location and Contact Information:
Additional Information:
Study ID Numbers: 4914;
Study Start Date: September 1990
Record last reviewed: May 2000
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00005469
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Maturational Changes in Cardiac Structures -- Blood Pressure Relationship -- SCOR in Hypertension
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