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Mapping the Areas of the Brain Associated with Language in Children with Epilepsy Clinical Trials Info presented on Clinical Trials Search isn't intended to be a substitute for certified health advice, travels to or treatment by using a genuine physician. We are not physicians. Always consult your dr. on Mapping the Areas of the Brain Associated with Language in Children with Epilepsy conditions. Clinical Trials Search.org is a site committed to listing clinical research studies in human subjects. Mapping the Areas of the Brain Associated with Language in Children with Epilepsy Clinical research trials and Mapping the Areas of the Brain Associated with Language in Children with Epilepsy health trials occur in hundreds of cities throughout the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectivity of new drugs. The propose of the studies / undertakings is to resolve certain human health questions. Clinical trials are a popular means for physicians, government agencies, and private sector companies to locate treatments for all sorts of conditions, including Mapping the Areas of the Brain Associated with Language in Children with Epilepsy. Mapping the Areas of the Brain Associated with Language in Children with Epilepsy Clinical Trials and other clinical trials permit volunteers to acquire medical treatment choices before they are available to the masses. Some times the test subjects obtain professional assistance for free, and every now and again they are compensated for their time. Sometimes there is a cost for a Mapping the Areas of the Brain Associated with Language in Children with Epilepsy clinical trial. Participants oftentimes recieve the most expert healthcare available for their Mapping the Areas of the Brain Associated with Language in Children with Epilepsy condition. Hazards are a reality, however, and can include extra or frequent physician visits, health risks (potentially life-endangering), and/or the treatment being uneffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.

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Mapping the Areas of the Brain Associated with Language in Children with Epilepsy



Mapping the Areas of the Brain Associated with Language in Children with Epilepsy

For Condition: Epilepsy,Seizures
Status: Completed
Sponsor(s): National Institute of Neurological Disorders and Stroke (NINDS) ,
Synopsis: Researchers are interested in studying if magnetic resonance imaging (MRI) is practical for locating the areas of the brain associated with language in children with epilepsy. When a region of the brain is active, it uses more fuel in the form of oxygen and sugar (glucose). As the brain uses more fuel it produces more waste products, carbon dioxide and water. Blood carries fuel to the brain and waste products away from the brain. As brain activity increases blood flow to and from the area of activity increases also. Patients participating in the study will be asked to perform tasks designed to test language skills while undergoing an MRI to detect areas of the brain using oxygen and receiving blood flow.
Details: We propose to study the feasibility of utilizing MRI to perform functional mapping of language cortex in children with epilepsy. We will use 1.5 Tesla MRI to study cerebral blood flow and tissue oxygenation during cognitive activation tasks derived from previous adult studies.
Eligibility:
Study Type:  Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: Children aged 5-17 years. Partial epilepsy (localized). Ability to cooperate with task paradigms (IQ greater than 65). No cardiac pacemakers, cochlear implants, shrapnel, vascular clips, braces, or claustrophobia. No one with inability to cooperate with task paradigms.
Total Enrollment: 230

Location and Contact Information:

National Institute of Neurological Disorders and Stroke (NINDS)
Bethesda,  Maryland,  20892
United States
 


Additional Information:
Study ID Numbers:  930191;  93-N-0191
Study Start Date: August 2, 1993
Record last reviewed: September 11, 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001366

Other Epilepsy Studies:
1. Human Epilepsy Genetics--Neuronal Migration Disorders Study

2. Monitoring Patients with Uncontrolled Epilepsy

3. Metabolic Abnormalities in Children with Epilepsy

4. Neuropsychological Evaluation of Psychiatric and Neurological Patients

5. Brain Tissue Swelling and Seizure Activity in Inactive Cysticercosis

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