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Mapping Personality Traits to Genes Clinical Trials Information presented on Clinical Trials Search isn't intended to be a substitute for proven healthcare advice, trips or treatment using a real physician. We are not docs. Always confer with your mD on Mapping Personality Traits to Genes conditions. Clinical Trials Search.org is a site dedicated to listing clinical research studies in human subjects. Mapping Personality Traits to Genes Clinical research trials and Mapping Personality Traits to Genes medical trials take place in hundreds of localities across the U.S.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials usually measure the effectiveness of new drugs. The intention of the studies / projects is to resolve certain human health questions. Clinical trials are a popular means for physicians, government agencies, and private sector corporations to detect remedies for all forms of circumstances, like Mapping Personality Traits to Genes. Mapping Personality Traits to Genes Clinical Trials and other clinical trials allow for volunteers to undergo healthcare treatment options before they are available to the masses. Most times the participants receive treatment for free, and every now and again they are paid for their time. Occasionally there is a cost for a Mapping Personality Traits to Genes clinical trial. Subjects typically recieve the finest healthcare available for their Mapping Personality Traits to Genes condition. Hazards are a reality, nonetheless, and might include more or frequent mD trips, health risks (potentially life-endangering), and/or the treatment being ineffective. Trials are federally regulated with stern guidelines to protect clinical trials subjects.
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Home > "M" Clinical Trials Conditions > Mapping Personality Traits to Genes  Mapping Personality Traits to Genes
Mapping Personality Traits to Genes
For Condition: Mental Disorder
Status: Completed
Sponsor(s): National Institute of Mental Health (NIMH) ,
Synopsis: Previous research involving families, twins, and adoption all support the idea that there is a substantial heritable aspect to personality. The goal of this research study is to determine how genetics influence heritable personality traits. The work will focus on how genetics affect the chemical messengers which brain cells use to communicate with each other (neurotransmitters). The study involves collecting personality data and DNA samples from related individuals, primarily male siblings and female siblings, but also including parents. Genetic tests performed on these samples will continue to focus on variations in genes, which potentially effect brain neurotransmission. This research has the potential to advance knowledge of genetic influences on human behavior that may be relevant both to normal personality and to psychopathology.
Details: Building on family, twin and adoption studies suggesting that substantial aspects of personality are heritable, research under this protocol explores potential genetic influences on normal personality dimensions. We have previously reported associations between variation in neurotransmitter system genes and variation in personality traits, both across and within families, in a sample of the general population. This study involves collecting personality data and DNA samples from related individuals, primarily male siblings and female siblings, but also including parents. Genetic tests performed on these samples will continue to focus on variations in genes, which potentially affect brain neurotransmission. In some cases, participants are recontacted to specifically investigate whether identified variations in neurotransmitter system genes actually affect neurotransmission. Large population samples are needed in this research, particularly since a new epidemiologically standard population sample will be obtained. This research has the potential to advance knowledge of genetic influences on human behavior that may be relevant both to normal personality and to psychopathology.
Eligibility:
Study Type: Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: Personality data and DNA samples will be collected from related individuals, primarily pairs of male and pairs of female siblings, but also including parents.
Total Enrollment: 2400
Location and Contact Information:
National Institute of Mental Health (NIMH)
Bethesda, Maryland, 20892
United States
Additional Information:
Study ID Numbers: 940122; 94-M-0122
Study Start Date: April 6, 1994
Record last reviewed: June 27, 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001414
Other Mental Disorder Studies:
1. Consequences of Conjugal Bereavement in Adults
2. Mapping Personality Traits to Genes
3. Neuropsychiatric Effects of Interferon-Alpha and Ribavirin
4. I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers
5. Test of A Model of Representational Knowledge Stored in the Human Prefrontal Cortex
Related Studies:
Other Mental Disorder Clinical Trials
Other Maryland Clinical Trials
Other Bethesda Clinical Trials
Mapping Personality Traits to Genes
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