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Home > "M" Clinical Trials Conditions > Magnetic Resonance Imaging at Different Levels of Magnetic Intensity  Magnetic Resonance Imaging at Different Levels of Magnetic Intensity
Magnetic Resonance Imaging at Different Levels of Magnetic Intensity
For Condition: Cardiovascular Disease,Healthy
Status: Recruiting
Sponsor(s): National Heart, Lung, and Blood Institute (NHLBI) ,
Synopsis: Magnetic resonance imaging (MRI) is a diagnostic tool that creates high quality images of the human body without the use of X-ray (radiation). MRI uses different levels of magnetic fields to create images of the body and organs. Occasionally, researchers will give patients undergoing a MRI an injection of a substance called gadolinium. Gadolinium works by brightening areas of the magnetic resonance image, thereby improving the contrast. In this study researchers will use magnetic resonance imaging and contrast substances, like gadolinium, on normal volunteers in order to evaluate different aspects of its performance. Information gathered from this study may be used to develop more specific research studies involving MRI.
Details: Technical evaluation of magnetic resonance imaging and spectroscopy will be performed on normal volunteers. These studies may involve the intravenous administration of commercially available MR contrast media. The results will be used to evaluate the performance of various pulse sequences, gradient coils, and rf coils on human subjects and will provide essential ground work for specific patient protocols.
Eligibility:
Study Type: Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: INCLUSION CRITERIA: Any normal volunteer between ages 18 and 80 who is capable of giving informed consent. EXCLUSION CRITERIA: A subject will be excluded if he/she has a contraindication to MR scanning such as surgery that involved metal clips or wires which might be expected to concentrate radiofrequency fields or cause tissue damage from twisting twisting in a magnetic field. Examples include: Aneurysm clip; Implanted neural stimulator; Implanted cardiac pacemaker or autodefibrillator; Cochlear implant; Ocular foreign body (e.g. metal shavings); Insulin pump. Subjects will be excluded if it is deemed that they have a condition which would preclude their use for technical development (e.g. paralyzed hemidiaphragm, morbid obesity, claustrophobia, etc.) or present unnecessary risk (e.g. pregnancy, surgery of uncertain type, etc.). Lactating women and subjects with hemoglobinopathies, asthma, or renal or hepatic disease will be excluded from studies involving the administration of contrast agents.
Total Enrollment: 400
Location and Contact Information:
National Heart, Lung and Blood Institute (NHLBI) *Recruiting*
Bethesda, Maryland, 20892
United States
Recruiting Patient and Public Liaison Office 1-800-411-1222
Additional Information:
Study ID Numbers: 970026; 97-H-0026
Study Start Date: November 5, 1996
Record last reviewed: October 16, 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001619
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5. Comparing Angiomax to Heparin with Protamine in Patients Undergoing Cardiopulmonary Bypass (CPB)
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Magnetic Resonance Imaging at Different Levels of Magnetic Intensity
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