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Living-Related Donor Bone Marrow Immunoregulation in Kidney Transplants



Living-Related Donor Bone Marrow Immunoregulation in Kidney Transplants

For Condition: Kidney Disease
Status: Recruiting
Sponsor(s): Department of Veterans Affairs Medical Research Service ,
Synopsis: Diabetes and end-stage kidney, liver and heart disease are prominent health issues among veteran patients. Successful solid organ transplantation in the absence of chronic immunosuppressive therapy (specific acquired immunological tolerance) is a desirable therapeutic option. This project extends recent observations supporting the use of concommitant donor bone marrow cell infusion as a means of medulating the immune response in kidney transplantation , thereby allowing a substantial decrease or withdrawal of potentially toxic immunosuppressive drugs.
Details:
Eligibility:
Study Type:
  Interventional, Prevention, Open Label, Active Control, Parallel Assignment, Efficacy Study
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: Living related donor kidney transplant recipients and the living related donors.
Total Enrollment: 

Location and Contact Information:

Overall Study Official:
VioletEsquenazi,  , 

VAMC Miami *Recruiting*
Miami,  Florida,  33125
United States
Recruiting Gustavo  Godoy 305-324-3179


Additional Information:
Study ID Numbers:
  IMMU-035-98S; 
Study Start Date: October 1998
Record last reviewed: June 2001
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00018785

Other Kidney Disease Studies:
1. Determination of Kidney Function

2. Effectiveness of the Investigational Drug Campath-1H in Preventing Rejection of Transplanted Kidneys

3. A Study of Zidovudine in HIV-Infected Patients with Kidney Problems

4. Living-Related Donor Bone Marrow Immunoregulation in Kidney Transplants

5. Evaluation of New Test Method to Measure Kidney Function

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Other Kidney Disease Clinical Trials
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Living-Related Donor Bone Marrow Immunoregulation in Kidney Transplants

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