|
Lipoprotein Metabolism in Normal Volunteers and Patients with Abnormal Levels of Lipoproteins Clinical Trials Facts presented on Clinical Trials Search is not designed to be a substitute for certified medical advice, travels to or treatment with a real dr.. We aren't doctors. Always consult your mD on Lipoprotein Metabolism in Normal Volunteers and Patients with Abnormal Levels of Lipoproteins conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Lipoprotein Metabolism in Normal Volunteers and Patients with Abnormal Levels of Lipoproteins Clinical research trials and Lipoprotein Metabolism in Normal Volunteers and Patients with Abnormal Levels of Lipoproteins medical trials occur in many of places across the U.S.A.. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally assess the effectiveness of new does drugs. The role of the studies / undertakings is to figure out certain human healthcare questions. Clinical trials are a popular means for doctors, government agencies, and private sector corporations to locate treatments for all forms of circumstances, including Lipoprotein Metabolism in Normal Volunteers and Patients with Abnormal Levels of Lipoproteins. Lipoprotein Metabolism in Normal Volunteers and Patients with Abnormal Levels of Lipoproteins Clinical Trials and other clinical trials permit volunteers to get medical treatment options before they are available to the masses. Most times the human subjects acquire treatment for free of charge, and sometimes they are paid for their time. Occasionally there is a cost for a Lipoprotein Metabolism in Normal Volunteers and Patients with Abnormal Levels of Lipoproteins clinical trial. Participants oftentimes recieve the finest healthcare available for their Lipoprotein Metabolism in Normal Volunteers and Patients with Abnormal Levels of Lipoproteins condition. Dangers are a reality, nonetheless, and might include extra or frequent physician calls, health hazards (potentially life-endangering), and/or the treatment being ineffectual. Trials are federally regulated with strict guidelines to protect clinical trials subjects.
|
|
|
|
|
|
|
Home > "L" Clinical Trials Conditions > Lipoprotein Metabolism in Normal Volunteers and Patients with Abnormal Levels of Lipoproteins  Lipoprotein Metabolism in Normal Volunteers and Patients with Abnormal Levels of Lipoproteins
Lipoprotein Metabolism in Normal Volunteers and Patients with Abnormal Levels of Lipoproteins
For Condition: Healthy,Hyperlipoproteinemia
Status: Completed
Sponsor(s): National Heart, Lung, and Blood Institute (NHLBI) ,
Synopsis: Researchers plan to study the fat-rich particles, called lipoproteins, which circulate in the blood. This study is designed to improve understanding of normal, as well as abnormal, lipoprotein metabolism and the role it plays in the development of hardening of the arteries (atherosclerosis). Patients participating in this study will receive an intravenous (directly into the vein) injection of a small amount of specially prepared amino acids. The amino acids being injected are the same amino acids present in a normal diet. The amount of amino acid given will be less than the amount eaten in a protein-rich meal. The amino acids will be labeled with nonradioactive heavy isotopes which are also present in the environment n low amounts. Patients participating in the study will be required to have blood samples taken, and provide urine samples throughout the course of the study. In addition, patient will be required to follow a specially formulated diet. Patients will be weighed throughout the course of the study.
Details: Apolipoproteins regulate the metabolism of lipids and lipoproteins in plasma of humans. In order to investigate the roles of apolipoproteins in these processes, we plan to quantitate the kinetics of the metabolism of apolipoproteins utilizing nonradioactive isotope labeled amino-acids.
Eligibility:
Study Type: Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: The subjects for these investigations will be either healthy normal volunteer control subjects or patients who have a dyslipoproteinemia. Subjects must be 18-80 years old.
Total Enrollment: 90
Location and Contact Information:
National Heart, Lung and Blood Institute (NHLBI)
Bethesda, Maryland, 20892
United States
Additional Information:
Study ID Numbers: 870207; 87-H-0207
Study Start Date: December 22, 1987
Record last reviewed: March 6, 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001226
Other Hyperlipoproteinemia Studies:
1. Evaluation of Lipoproteins
2. Lipoprotein Metabolism in Normal Volunteers and Patients with Abnormal Levels of Lipoproteins
Related Studies:
Other Hyperlipoproteinemia Clinical Trials
Other Maryland Clinical Trials
Other Bethesda Clinical Trials
Lipoprotein Metabolism in Normal Volunteers and Patients with Abnormal Levels of Lipoproteins
|
|
|
|
|
|
|
|
