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Islet Transplantation for patients with Type 1 diabetes Clinical Trials Resources presented on Clinical Trials Search isn't meant to be a substitute for qualified health advice, visits or professional assistance with a real medical. We aren't doctors. Always consult your mD about Islet Transplantation for patients with Type 1 diabetes conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Islet Transplantation for patients with Type 1 diabetes Clinical research trials and Islet Transplantation for patients with Type 1 diabetes health trials occur in a lot of of places throughout the United States of America. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials typically assess the effectivity of new does drugs. The role of the studies / projects is to resolve certain human healthcare questions. Clinical trials are a popular way for doctors, government agencies, and private sector corporations to detect remedies for all varieties of circumstances, such as Islet Transplantation for patients with Type 1 diabetes. Islet Transplantation for patients with Type 1 diabetes Clinical Trials and other clinical trials allow volunteers to obtain health treatment choices before they are available to the general public. Most times the human subjects recieve professional assistance for free of charge, and every now and again they are paid for their time. Sometimes there is a cost for a Islet Transplantation for patients with Type 1 diabetes clinical trial. Human subjects frequently get the finest healthcare available for their Islet Transplantation for patients with Type 1 diabetes condition. Risks are a reality, however, and may include extra or frequent physician visits, medical dangers (possibly life-threatening), and/or the treatment being uneffective. Trials are federally governed with strict guidelines to protect clinical trials patients.

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Islet Transplantation for patients with Type 1 diabetes



Islet Transplantation for patients with Type 1 diabetes

For Condition: Diabetes Mellitus, Type 1
Status: Recruiting
Sponsor(s): National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ,
Synopsis: This protocol will test whether Type 1 diabetes (T1DM) can be reversed in patients with stable renal allografts by islet transplantation.
Details: We will test whether pancreatic islets isolated from cadaveric human donor pancreata can be transplanted into the portal vein of patients with T1DM who have stable renal allografts to achieve insulin independence for the recipient. The protocol will employ a defined islet isolation procedure, percutaneous islet infusion into the recipient's portal vein via an intra-portal catheter, tight glycemic control during the peri-transplant period, and an immunosupperesive protocol that avoids glucocorticoids.
Eligibility:
Study Type:
  Interventional, Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/65 Years
Genders: Both
Protocol Entry Criteria: Patients with type 1 diabetes with stable renal allografts
Total Enrollment: 10

Location and Contact Information:

Overall Study Official:
MarkHardy,  Principal Investigator,  Columbia Presbyterian Hospital

Columbia Presbyterian Medical Center *Recruiting*
New York City,  New York,  10032
United States
Recruiting Kevan  Herold 212-342-3253


Additional Information:
Study ID Numbers:
  9903; 
Study Start Date: August 2003
Record last reviewed: November 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00073281

Other Diabetes Mellitus, Type 1 Studies:
1. Evaluation of the Effect of Pramlintide on Satiety and Food Intake

2. Evaluation of the Bioavailability of Pramlintide

3. Single Dose and 34-Day Tolerance Study of INGAP Peptide in Insulin Deficient Patients

4. Islet Cell Transplantation Alone in Patients with Type I Diabetes Mellitus: steroid-free immunosuppression

5. The Diabetes Prevention Trial of Type 1 Diabetes (DPT-1)

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