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Home > "I" Clinical Trials Conditions > Intracellular Pharmacokinetics of Zidovudine Triphosphate in Maternal and Infant Cord Blood Mononuclear Cells.

Intracellular Pharmacokinetics of Zidovudine Triphosphate in Maternal and Infant Cord Blood Mononuclear Cells.



Intracellular Pharmacokinetics of Zidovudine Triphosphate in Maternal and Infant Cord Blood Mononuclear Cells.

For Condition: HIV Infections,Pregnancy
Status: Completed
Sponsor(s): National Institute of Allergy and Infectious Diseases (NIAID) ,
Synopsis: To determine the levels of zidovudine triphosphate ( AZT-TP ) in maternal and fetal cord blood mononuclear cells. To determine the ratio of AZT-TP to endogenous nucleoside triphosphate levels in maternal and fetal cells. To determine the extent of drug transfer through the feto/placental unit.
Details:
Eligibility:
Study Type:
  Observational, Natural History
Minimum Age/Maximum Age: 18 Years/
Genders: Female
Protocol Entry Criteria: 
Total Enrollment: 24

Location and Contact Information:

Overall Study Official:
FridlandA,  Study Chair, 

San Juan City Hosp
San Juan,  ,  009367344
Puerto Rico
 

Bellevue Hosp / New York Univ Med Ctr
New York City,  New York,  10016
United States
 

Mount Sinai Med Ctr / Pediatrics
New York City,  New York,  10029
United States
 

Univ of Medicine & Dentistry of New Jersey / Univ Hosp
Newark,  New Jersey,  071032714
United States
 

Regional Med Ctr at Memphis
Memphis,  Tennessee,  38103
United States
 

Saint Jude Children's Research Hosp of Memphis
Memphis,  Tennessee,  381052794
United States
 


Additional Information:
Study ID Numbers:
  ACTG 296; 
Study Start Date: 
Record last reviewed: March 1998
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00000830

Other Hiv Infections Studies:
1. Vulnerability of the Fetus/Infant to PAH, PM2.5 AND ETS.

2. Prenatal Screening For Smith-Lemli-Opitz Syndrome

3. A Study to Evaluate the Safety and Tolerance of Nelfinavir (NFV) Given with Zidovudine (ZDV) and Lamivudine (3TC) in HIV-Positive Pregnant Women and Their Infants

4. Problems Associated with the Use of Anti-HIV Drugs in HIV-Infected Pregnant Women

5. Quick Start Approach to Birth Control Pills

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Intracellular Pharmacokinetics of Zidovudine Triphosphate in Maternal and Infant Cord Blood Mononuclear Cells.

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