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Home > "I" Clinical Trials Conditions > Insulin Resistance and Insulin Secretion  Insulin Resistance and Insulin Secretion
Insulin Resistance and Insulin Secretion
For Condition: Diabetes Mellitus, Type 2
Status: Recruiting
Sponsor(s): National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) ,
Synopsis: This is a pilot study to examine the prevalence of metabolic risk factors (impaired insulin release and impaired insulin sensitivity) for type 2 diabetes mellitus in children and adults from a population that is at high risk for this disease. We hypothesize that at least one of these pre-diabetic traits will be evident in a large proportion of relatives of known type 2 diabetic children as compared to a control group of subjects without a family history of type 2 diabetes. By isolating these traits, it will be possible to determine the relative contributions of genes and environment to each trait and to identify those at risk for subsequent development of type 2 diabetes by virtue of having one trait. Ultimately, those individuals at risk, especially those with impaired insulin release, would hopefully benefit from intervention to prevent the weight gain that will 'unmask' their underlying pancreatic dysfunction and thus prevent or retard the development of type 2 diabetes.
Details:
Eligibility:
Study Type: Interventional, Prevention, Non-Randomized, Single Blind, Uncontrolled, Single Group Assignment, Bio-equivalence Study
Minimum Age/Maximum Age: 10 Years/20 Years
Genders: Both
Protocol Entry Criteria: Ascertainment criteria for probands: - age 10-20 years and - obesity (BMI >85% for sex and age) - diabetic criteria as described above or family history (first or second degree relative) with type 2 diabetes
Total Enrollment: 200
Location and Contact Information:
Columbia Presbyterian Medical Center/ Irving Center *Completed*
New York City, New York, 10032
United States
Completed
Russ Berrie Pavilion *Recruiting*
New York City, New York, 10032
United States
Recruiting Michael Rosenbaum
Additional Information:
Study ID Numbers: 9777;
Study Start Date:
Record last reviewed: November 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00073294
Other Diabetes Mellitus, Type 2 Studies:
1. Randomized Trial of Health Events Costs in Diabetic Blacks
2. Native Hawaiian Diabetes Intervention Program
3. Lifestyle interventions to reduce diabetes risk
4. NEW DAY: Nutrition, Exercise, Weight loss, Diabetes And You
5. Single Dose and 34-Day Tolerance Study of INGAP Peptide in Insulin Deficient Patients
Related Studies:
Other Diabetes Mellitus, Type 2 Clinical Trials
Other New York Clinical Trials
Other New York City Clinical Trials
Insulin Resistance and Insulin Secretion
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