Texas Clinical
Trials By City

Houston Texas Clinical Trials

An Observational Study of Hepatitis C Virus in Pregnancy
This multi-center observational study examines risk factors for HCV transmission from mother to baby.
Status: Recruiting Start Date: October 2012 Completion Date: April 2019
Hatha Yoga in Lung Cancer Couples
The goal of this research study is to learn the opinion of patients and their caregiving about a couple-based Hatha Yoga program during treatment for cancer. Researchers also want to learn the effect of this program on lung function, distress, and quality of [more...]  life.
Status: Recruiting Start Date: September 2013 Completion Date: 
Hypofractionated Proton Beam Therapy for Localized Prostate Cancer
The goal of this clinical research study is to learn if delivering proton therapy in higher doses per treatment may help control prostate cancer just as well as the standard of care treatment. The safety of this treatment will also be studied. [more...]  Radiation dose is measured in units called Gray (Gy). The standard of care treatment schedule for proton therapy is 1.8-2 Gy, given 1 time per day, 5 days per week over a period of 8-9 weeks.
Status: Recruiting Start Date: October 2013 Completion Date: 
A Study of Demcizumab Plus Paclitaxel in Subjects With Platinum Resistant Ovarian
This is a Phase 1b/2 study of paclitaxel plus demcizumab in subjects with platinum resistant ovarian, primary peritoneal or fallopian tube cancer.
Status: Recruiting Start Date: August 2013 Completion Date: October 2015
The PIONEER-01 Pivotal Study of the Imagio Breast Imaging System
Imagio is a multi-modality device, comprised of opto-acoustic (OA) imaging co-registered with diagnostic grey-scale (B mode) ultrasound, that has been designed to concurrently collect OA images in conjunction with diagnostic grey-scale (B-mode) ultrasound. Imagio is expected to identify two [more...]  functional hallmarks of a potential malignancy: the presence of abnormal blood vessels (angiogenesis); and the relative reduction in oxygen content of hemoglobin. The technology is non-invasive and does not require any contrast agent or radio-isotope, which is required for other modalities such as MRI or PET. This is a prospective, single arm, controlled, multi-center, observational study that will compare Imagio versus conventional diagnostic ultrasound (CDU) for the visualization of suspicious masses.
Status: Recruiting Start Date: July 2013 Completion Date: January 2015
Crossover Trial of Systemic Chemotherapy in Patients With Metastatic Well-differentiated Mucinous Appendiceal Adenocarcinomas With Pseudomyxoma Peritonea
Appendiceal cancer is a rare disease that does not cause many symptoms. As such, doctors are not sure if chemotherapy actually has an effect on the disease. The goal of this clinical research study is to learn more about the effects that [more...]  chemotherapy may have on appendiceal cancer.
Status: Recruiting Start Date: July 2013 Completion Date: 
A Study to Evaluate the Safety and Efficacy of ABT-450/Ritonavir/ABT-267 (ABT-450/r/ABT-267) and ABT-333 Coadministered With Ribavirin (RBV) in Adults With Genotype 1 Chronic Hepatitis C Virus (HCV) Infection and Human Immunodeficiency Virus, Type 1 (HIV-1) Coinfection
The purpose of this study is to evaluate the safety and efficacy of ABT-450/r/ABT-267 and ABT-333 coadministered with RBV in HCV genotype 1 adults with HIV-1 coinfection.
Status: Recruiting Start Date: August 2013 Completion Date: November 2015
Evaluation of ETC-1002, Ezetimibe, and the Combination in Hypercholesterolemic Patients
The purpose of this research study is to see how ETC-1002 is tolerated in the body, to measure the amount of ETC-1002 in the blood, and to determine how ETC-1002 affects the [more...]  level of LDL-cholesterol (bad cholesterol) and other markers of health and disease in blood and urine in patients with elevated LDL-cholesterol with or without statin intolerance.
Status: Recruiting Start Date: September 2013 Completion Date: December 2014
Gemcitabine Pharmacokinetics After Preoperative Chemoradiation Therapy
The goal of this clinical research study is to learn if gemcitabine given during surgery can enter pancreas cancer cells in patients who have already received chemotherapy and radiation. Gemcitabine is a drug used to treat pancreatic cancer. [more...]  However, it has not previously been studied if gemcitabine can enter pancreatic cancer cells. Gemcitabine is designed to block the growth of cancer cells, which may cause cancer cells to die.
Status: Recruiting Start Date: March 2012 Completion Date: 
Candesartan as a Treatment for Cocaine Dependence
The purpose of this study is to see if a drug called Candesartan will help to reduce use of cocaine.
Status: Recruiting Start Date: January 2013 Completion Date: January 2014
H7N9 Mix and Match With AS03 and MF59 in Healthy Adults
This Phase II randomized, double-blinded, controlled study in up to 1000 males and non-pregnant females, 19 to 64 years old, inclusive, who are in good health and meet all eligibility criteria is designed to provide data on an A/H7N9 vaccine made with HA antigen [more...]  derived from the influenza A/Shanghai/2/2013 virus.
Status: Recruiting Start Date: September 2013 Completion Date: December 2014
A Phase 2 Study to Evaluate the Efficacy and Safety of AMG 334 in Migraine Prevention
Randomized, double-blind, placebo-controlled, parallel-group, multi-center study followed by open-label phase. To evaluate the effect of AMG 334 compared to placebo on the change from baseline in monthly migraine days
Status: Recruiting Start Date: August 2013 Completion Date: July 2015
A Prospective Observational Study to Evaluate Acute Kidney Injury Biomarkers In Patients Receiving First Cycle of Cisplatin Chemotherapy for Head and Neck Cancers
The project is designed to test new biomarkers that are more sensitive than the current standard in detecting injury to the proximal kidney tubule and will establish better criteria for when kidney safety concerns may halt further testing of a drug in humans.
Status: Recruiting Start Date: September 2012 Completion Date: December 2014
A Global Phase 3 Study to Evaluate the Safety and Efficacy of Elagolix in Subjects With Moderate to Severe Endometriosis-Associated Pain
A randomized study evaluating the safety and efficacy of elagolix in the management of moderate to severe endometriosis-associated pain in adult premenopausal female subjects.
Status: Recruiting Start Date: September 2013 Completion Date: April 2016
A Feasibility Study of Prophylactic White Blood Cell Transfusions
Patients with leukemia often have low white blood cell counts after chemotherapy, which puts them at greater risk of infection. The standard of care for preventing infections is to give these patients antibiotic, antifungal, and antiviral drugs during the time that white blood [more...]  cell counts are low. However, many patients still develop infections during chemotherapy. Radiated white blood cell transfusions are a standard treatment once a patient develops a severe infection. The goal of this clinical research study is to learn if giving white blood cell transfusions that are not radiated early in chemotherapy might delay or prevent infections in patients with leukemia. Researchers also want to learn more about the type and severity of any infections that do occur.
Status: Recruiting Start Date: September 2013 Completion Date: 
Effect of Perioperative Intravenous Lidocaine on Postoperative Quality of Recovery in Patients Undergoing Spine Surgery
Acute postoperative pain is an unpleasant, unwanted sensory and emotional experience for the patient. The investigators seek to determine if the addition of systemic lidocaine can improve the quality of recovery after spine surgery and reduce the requirement for opiate [more...]  therapy.
Status: Recruiting Start Date: August 2013 Completion Date: September 2014
NECTAR Everolimus Plus Cisplatin in Triple (-) Breast Cancer
RATIONALE: Everolimus plus Cisplatin may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. PURPOSE: The purpose of this study is to test how effective combing a Cisplatin [more...]  chemotherapy with Everolimus is in treating subjects with residual triple negative breast cancer, who have already received chemotherapy prior to surgery.
Status: Recruiting Start Date: July 2013 Completion Date: August 2016
Effect of Pumpkin Seeds on the Dietary Fatty Acid Intake and Blood Pressure in Women
The purpose of this study is to determine if the inclusion of 1.5 ounces of pumpkin seeds per day in the diet of women will alter dietary fatty acid intake or blood pressure.
Status: Recruiting Start Date: August 2013 Completion Date: January 2014
Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Positive Hepatitis B
The purpose of this study is to evaluate the safety and efficacy of tenofovir alafenamide (TAF) compared to that of tenofovir disoproxil fumarate (TDF) in treatment naive and experienced adult subjects with chronic hepatitis B virus (HBV) infection, as determined by [more...]  the achievement of HBV DNA < 29 IU/mL at Week 48.
Status: Recruiting Start Date: September 2013 Completion Date: May 2018
Tenofovir Alafenamide Versus Tenofovir Disoproxil Fumarate for Treatment of Hepatitis B e Antigen-Negative Hepatitis B
The purpose of this study is to evaluate the safety and efficacy of tenofovir alafenamide (TAF) compared to that of tenofovir disoproxil fumarate (TDF) in treatment naive and experienced adult subjects with chronic hepatitis B virus (HBV) infection, as determined by [more...]  the achievement of HBV DNA < 29 IU/mL at Week 48.
Status: Recruiting Start Date: September 2013 Completion Date: February 2018
Oral Rigosertib in Combination With Azacitidine
This study, as a Phase I/II clinical trial, has two parts. The objective in the first part of this study is to determine the largest dose of the experimental anti-cancer drug, oral rigosertib, that can be given safely in combination with azacitidine. Azacitidine is [more...]  an approved drug used to treat patients with myelodysplastic syndrome (MDS). The second part of the study will assess if treatment with rigosertib (at the dose determined in the first part), in combination with azacitidine, has measurable effects in patients with MDS and other diseases. Safety of patients is an objective throughout both parts of the study.
Status: Recruiting Start Date: August 2013 Completion Date: August 2015
Safety and Efficacy Study of Apremilast to Treat Psoriatic Arthritis
The purpose of this study is to determine whether apremilast is safe and effective for treating patients with psoriatic arthritis.
Status: Recruiting Start Date: August 2013 Completion Date: January 2017
Efficacy and Safety of Bimagrumab/BYM338 at 52 Weeks on Physical Function, Muscle Strength, Mobility in sIBM Patients
To evaluate the efficacy, safety and tolerability of multiple doses of bimagrumab/BYM338 vs placebo, when administered intravenously (i.v.), on physical function, muscle strength, and mobility in patients with sporadic inclusion body myositis (sIBM)
Status: Recruiting Start Date: September 2013 Completion Date: November 2015
BAP1 Testing in Instance Choroidal Nevi
BAP1 serum germline, is a simple blood test in patients with nevi. This study aims to examine the rate of germline BAP1 mutations in young patients diagnosed with choroidal nevi to explore the role for this test as a screening tool in the future [more...]  in this particular patient population.
Status: Recruiting Start Date: July 2013 Completion Date: 
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Clinical trials allow volunteers access to medical treatment options before they are available to the general public. Participants often receive the best healthcare available for their condition.

Risks are a reality, however, and may include more frequent doctor visits, health risks (possibly life-threatening), and/or the treatment being ineffective. Trials are federally regulated with strict guidelines to protect participants.

Houston Texas Clinical Trials Information presented on ClinicalTrialsSearch.org is not intended to be a substitute for qualified medical advice visit or treatment with a real physician. We are not physicians. Always consult with a medical doctor (MD). ClinicalTrialsSearch.org is a website dedicated to listing clinical research studies in human subjects, including those specifically related to Houston Texas. Clinical research trials and medical trials take place in hundreds of cities across the United States. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally measure the effectiveness of new treatments and drugs. The purpose of the studies is to answer specific human health questions. Clinical trials are a popular way for doctors, government agencies, and private sector companies to find treatments for all kinds of conditions. Clinical trials allow volunteers access to medical treatment options before they are available to the general public. Many times the participants receive treatment for free, and sometimes they are paid for their time. Participants often receive the best healthcare available possible for their condition. Risks are a reality, however, and may include more frequent doctor visits, health risks (possibly life-threatening), and/or the treatment being ineffective. U.S. - based Houston Texas studies are federally regulated with strict guidelines to protect patients.

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Feeling Depressed? A clinical trial might help.
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The State of Constipation Clinical Trials
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Constipation is a illness where the bowels cannot move waste material out of the body in a normal manner. There are various clinical trials recruiting participants to study the effectiveness of various treatments.

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