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High Intensity Light Therapy in Alzheimer's Disease



High Intensity Light Therapy in Alzheimer's Disease

For Condition: Alzheimer's Disease,Dementia
Status: Recruiting
Sponsor(s): National Center for Complementary and Alternative Medicine (NCCAM) , National Institute on Aging (NIA)
Synopsis: The purpose of this study is to determine whether bright light improves the sleep, mood, and behavior of persons with Alzheimer's disease and related dementias (AD) who live in long-term care settings and, if so, to determine the best timing for the light therapy. The light levels being used in the study have been shown to improve depression in persons with seasonal affective disorder (SAD) and to relieve sleep problems in persons with jet lag and other body rhythm disturbances. Because persons with AD often will not remain still in front of a fluorescent panel, this project has involved renovations in the study units that provide for even, regulated, high-intensity light in all public areas of the study settings.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Single Blind, Dose Comparison, Crossover Assignment, Efficacy Study
Minimum Age/Maximum Age: 60 Years/
Genders: Both
Protocol Entry Criteria: Inclusion criteria: - Diagnosis of dementia - Residence on study units Exclusion criteria: - Bipolar disorder - Severe retinal (eye) disease
Total Enrollment: 180

Location and Contact Information:

Overall Study Official:
PhilipSloane,  Principal Investigator, 

John Umstead Hospital *Recruiting*
Butner,  North Carolina,  27514
United States
Recruiting C.  Mitchell 919-966-6074


Additional Information:
Study ID Numbers:
  1 R01 AT00212-01A1;  SloaneP
Study Start Date: March 2003
Record last reviewed: March 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00065689

Other Dementia Studies:
1. Alzheimer's Disease and Aging: Therapeutic potential of estrogen

2. Randomized Safety, Tolerability and Pilot Efficacy of AN-1792 in Alzheimer's Disease

3. PET Scan of Brain Metabolism in Relation to Age and Disease

4. Prevention of cognitive decline in Alzheimer's disease by ingested interferon alpha

5. Study of an Investigational Drug for the treatment of Alzheimer's Disease

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High Intensity Light Therapy in Alzheimer's Disease

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