|
Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits Clinical Trials Facts presented on Clinical Trials Search is not designed to be a substitute for certified medical advice, travels to or professional assistance by using a genuine doctor. We aren't mDs. Always consult your physician about Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits conditions. Clinical Trials Search.org is a website committed to listing clinical research studies in human subjects. Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits Clinical research trials and Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits health trials occur in a lot of of cities throughout the US. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally evaluate the potency of new does drugs. The role of the studies / undertakings is to figure out specific human healthcare questions. Clinical trials are a popular manner for mDs, government agencies, and private sector companies to locate treatments for all sorts of conditions, including Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits. Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits Clinical Trials and other clinical trials permit volunteers to get medical treatment choices before they are available to the general public. Many times the test subjects get professional assistance for free of charge, and occasionally they are compensated for their time. Sometimes there is a cost for a Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits clinical trial. Human subjects often get the best healthcare possible for their Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits condition. Risks are a reality, nevertheless, and could include additional or frequent dr. calls, medical hazards (perhaps life-threatening), and/or the treatment being ineffectual. Trials are federally governed with exacting guidelines to protect clinical trials patients.
|
|
|
|
|
|
|
Home > "G" Clinical Trials Conditions > Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits  Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits
Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits
For Condition: Acquired Immunodeficiency Syndrome,Alcoholism,HIV Infection,Neoplasm,Smoking
Status: No longer recruiting
Sponsor(s): National Cancer Institute (NCI) ,
Synopsis: We propose to conduct a multifactorial genetic study of cancer risk-related behaviors and other complex human characteristics. The main areas of interest are tobacco smoking, excess alcohol consumption, psychological traits, and HIV/AIDS susceptibility and progression. The subjects will be adult male and female probands who display one or more of the phenotypes of interest together with their brothers, sisters and parents. Information on tobacco and alcohol use, psychological and personality traits, sexual behavior, HIV status and progression, and other characteristics with possible genetic components will be obtained through structured interviews and questionnaires. DNA will be prepared from blood samples and typed for a series of candidate genes chosen for function and for random polymorphic markers. By correlating the genotypic and phenotypic information, we hope to identify individual loci that interactively contribute to many different aspects of human health and disease.
Details: We propose to conduct a multifactorial genetic study of cancer risk-related behaviors and other complex human characteristics. The main areas of interest are tobacco smoking, excess alcohol consumption, psychological traits, and HIV/AIDS susceptibility and progression. The subjects will be adult male and female probands who display one or more of the phenotypes of interest together with their brothers, sisters and parents. Information on tobacco and alcohol use, psychological and personality traits, sexual behavior, HIV status and progression, and other characteristics with possible genetic components will be obtained through structured interviews and questionnaires. DNA will be prepared from blood samples and typed for a series of candidate genes chosen for function and for random polymorphic markers. By correlating the genotypic and phenotypic information, we hope to identify individual loci that interactively contribute to many different aspects of human health and disease.
Eligibility:
Study Type: Observational, Natural History
Minimum Age/Maximum Age: /
Genders: Both
Protocol Entry Criteria: INCLUSION CRITERIA: The basic requirement for entry in the study will be the presence of any individual smoker who is willing to complete the evaluation process and donate a blood sample. Additional siblings will be encouraged but not required to participate. Probands will be recruited through smoking cessation programs at the National Naval Medical Center. Attendees at programs offered by the Health Promotions Department and the Military Family Health Center will be invited to participate in this study. EXCLUSION CRITERIA: All subjects will be adults (greater than 18 years). There will be no exclusions based on sex, ethnic group, or race.
Total Enrollment: 4500
Location and Contact Information:
National Cancer Institute (NCI)
Bethesda, Maryland, 20892
United States
Additional Information:
Study ID Numbers: 960061; 96-C-0061
Study Start Date: April 15, 1996
Record last reviewed: March 26, 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00001500
Other Alcoholism Studies:
1. Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits
2. A Pilot Study to Investigate the Clinical Utility of the Peregrine Monte Carlo Dose Calculation System for Radiation Therapy Treatment Planning
3. A Phase I Trial of ZD1694 (TOMUDEX), an Inhibitor of Thymidylate Synthase, in Pediatric Patients with Advanced Neoplastic Disease
4. Continuing Care and Treatment for Patients with Cancer/AIDS/Skin Disease
5. 2-Methoxyestradiol (2-ME2) to Treat Solid Tumor Cancers
Related Studies:
Other Alcoholism Clinical Trials
Other Maryland Clinical Trials
Other Bethesda Clinical Trials
Genetic Factors and Interrelationships for Cancer Risk-Related Behaviors and Complex Traits
|
|
|
|
|
|
|
|
