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Home > "E" Clinical Trials Conditions > Exposure, Dose, Body Burden and Health Effects of Lead  Exposure, Dose, Body Burden and Health Effects of Lead
Exposure, Dose, Body Burden and Health Effects of Lead
For Condition: Lead Poisoning
Status: No longer recruiting
Sponsor(s): National Institute of Environmental Health Sciences (NIEHS) ,
Synopsis: This is a study of the effects that lead has on the health of the central nervous system (for example, memory), peripheral nervous system (for example, sensation and strength in the hands and fingers), kidneys, blood pressure, and the blood forming system. A total of 803 lead workers and 135 persons without occupational lead exposure are being studied in South Korea. Lead in the body is being assessed by measurement of blood lead, chelatable lead (an estimate of lead in the tissues), and lead in bone. Subjects are tested three times each over three years. Several genetic factors are also being assessed for the role they play in the health effects of lead. These genes are known to differ among individuals. We are interested to know whether different forms of the same genes can modify the effect lead has on health.
Details:
Eligibility:
Study Type: Observational, Natural History, Longitudinal, Defined Population, Prospective Study
Minimum Age/Maximum Age: 17 Years/70 Years
Genders: Both
Protocol Entry Criteria: Lead workers in South Korea in one of 26 specific lead-using facilities. Population controls in South Korea.
Total Enrollment: 944
Location and Contact Information:
Additional Information:
Study ID Numbers: 7198-CP-001;
Study Start Date: February 1997
Record last reviewed: July 2002
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00013819
Other Lead Poisoning Studies:
1. Randomized Study of Succimer (Dimercaptosuccinic Acid) on Growth of Lead-Poisoned Children
2. Exposure, Dose, Body Burden and Health Effects of Lead
3. Effect of environmental exposures on the egg fertilizing ability of human sperm
4. Lead Mobilization & Bone Turnover in Pregnancy/Lactation
5. Lead, Endocrine Disruption and Reproductive Outcomes
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Exposure, Dose, Body Burden and Health Effects of Lead
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