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Evaluation of the Effect on Glucose Control and Safety of AC2993 in Patients With Type 2 Diabetes Treated With Metformin, Sulfonylurea, or Metformin and Sulfonylurea Combination



Evaluation of the Effect on Glucose Control and Safety of AC2993 in Patients With Type 2 Diabetes Treated With Metformin, Sulfonylurea, or Metformin and Sulfonylurea Combination

For Condition: Diabetes Mellitus, Non-Insulin-Dependent
Status: No longer recruiting
Sponsor(s): Amylin Pharmaceuticals ,
Synopsis: This multi-center, open-label study is designed to examine the effects on long-term glucose control and safety of AC2993 in patients with type 2 diabetes treated with metformin, sulfonylurea, or metformin and sulfonylurea combination.
Details:
Eligibility:
Study Type:
  Interventional, Treatment, Safety/Efficacy Study
Minimum Age/Maximum Age: 20 Years/75 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Subjects with type 2 diabetes - Treated for at least 3 months prior to screening either with metformin, sulfonylurea, or metformin and sulfonylurea combination - BMI 25-45 kg/m^2 - HbA1c between 7.5 % and 12.5 %, inclusive Exclusion Criteria: - Treated with other oral anti-diabetic agents other than metformin and sulfonylureas within 3 months of screening - Patients previously treated with AC2993 - Patients presently treated with insulin
Total Enrollment: 

Location and Contact Information:

Peterfy Teaching Hospital
Budapest,  ,  H 1076
Hungary
 

Uzsoki Street Municipal Hospital
Budapest,  ,  H 1145
Hungary
 

Diagnostic Units Hungary Kft.
Budapest,  ,  H 1036
Hungary
 


Additional Information:
Study ID Numbers:
  2993-117; 
Study Start Date: 
Record last reviewed: February 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00044668

Other Diabetes Mellitus, Non-Insulin-Dependent Studies:
1. Identification and therapy efficacy of Type 2 diabetes in Hispanic patients

2. A Research Study to Assess the Mechanism By Which Glucovance, Metformin, and Glyburide Work To Control Glucose Levels In Patients With Type 2 Diabetes

3. The ORIGIN Trial (Outcome Reduction with Initial Glargine Intervention)

4. NNC 90-1170 Mechanism of Action: A double-blind, randomized, single-center, placebo-controlled, crossover study to examine beta-cell responsiveness to graded glucose infusion in subjects with type 2 diabetes

5. Evaluation of the Effect on Glucose Control and Safety of AC2993 in Patients With Type 2 Diabetes Treated With Metformin, Sulfonylurea, or Metformin and Sulfonylurea Combination

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Evaluation of the Effect on Glucose Control and Safety of AC2993 in Patients With Type 2 Diabetes Treated With Metformin, Sulfonylurea, or Metformin and Sulfonylurea Combination

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