|
Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure. Clinical Trials Facts presented on Clinical Trials Search isn't designed to be a substitute for proven healthcare advice, calls or treatment using a real mD. We aren't mDs. Always confer with your physician on Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure. conditions. Clinical Trials Search.org is a website dedicated to listing clinical research studies in human subjects. Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure. Clinical research trials and Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure. healthcare trials happen in a lot of of localities across the United States of America. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials generally measure the potency of new drugs. The aim of the studies / undertakings is to answer particular human medical questions. Clinical trials are a popular manner for doctors, government agencies, and private sector corporations to discover remedies for all kinds of circumstances, such as Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure.. Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure. Clinical Trials and other clinical trials allow volunteers to get healthcare treatment alternatives before they are available to the general public. Most times the participants receive treatment for without cost, and occasionally they are paid for their time. Sometimes there is a cost for a Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure. clinical trial. Human subjects often receive the most effective healthcare possible for their Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure. condition. Risks are a reality, nonetheless, and may include more or frequent dr. calls, healthcare hazards (perhaps life-threatening), and/or the treatment being ineffective. Trials are federally governed with rigorous guidelines to protect clinical trials subjects.
|
|
|
|
|
|
|
Home > "E" Clinical Trials Conditions > Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure.  Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure.
Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure.
For Condition: Heart Failure, Congestive
Status: Recruiting
Sponsor(s): Abbott Laboratories ,
Synopsis: The purpose of this study is to evaluate the efficacy of a 24-hour infusion of levosimendan compared with placebo in the treatment of decompensated chronic heart failure.
Details:
Eligibility:
Study Type: Interventional, Treatment, Randomized, Double-Blind, Placebo Control, Single Group Assignment, Efficacy Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - A written informed consent must be obtained for hospitalized male or female patients over 18 years old of age. - The eligible patients must be diagnosed with worsening heart failure as evidenced by dyspnea at rest, poor ejection fraction and have been treated with IV diuretics. - It is allowable for the patients to be treated with IV inotropes and vasodilators. Exclusion Criteria: The following criteria would exclude the patient from study: - invasive cardiac procedure (e.g. cardiac surgery, LVAD, cardioversion, cardiac re-synchronization), - rhythm disorders (e.g. earlier Torsades de Pointes, increased heart rate), - severe ventricular outflow obstruction, - angina, - hypotension, - uncorrected hypokalemia, - CNS (e.g. stroke, TIA), - respiratory (e.g. COPD, intubated patients, oral, - intravenous or intramuscular steroids), - renal insufficiency (e.g. increased serum creatinine, dialysis), - hepatic impairment (e.g. significant increase in liver enzymes), - decompensation from active infection and acute bleeding (e.g. severe anemia). - Female patients of child bearing potential must have a negative pregnancy test and use adequate contraceptive precautions. - Also excluded is the use of amrinone and milrinone prior to randomization, a history of hypersensitivity to levosimendan or any of the excipients and previous participation in a clinical trial with any experimental treatment within the last 30 days.
Total Enrollment:
Location and Contact Information:
Cardiovascular Medical Group & Research Institute *Recruiting*
Beverly Hills, California, 90210
United States
Recruiting
Launceston General Hospital/Cardiac Research Unit *Recruiting*
Launceston, Tasmania, 7250
Australia
Recruiting
The Princess Alexandra Hospital *Recruiting*
Woolloongabba, Queensland, 4102
Australia
Recruiting
VA Hospital of San Francisco *Recruiting*
San Francisco, California, 94121
United States
Recruiting
St. Vincent's Hospital *Recruiting*
New York City, New York, 10011
United States
Recruiting
Hennepin County Medical Center *Recruiting*
Minneapolis, Minnesota, 55414
United States
Recruiting
Heart Failure & Transplantation Program *Recruiting*
Newark, New Jersey, 07112
United States
Recruiting
Austin-Cardiovascular Associates *Terminated*
Austin, Texas, 78705
United States
Terminated
Victor Howard M.D., P.A. Heart Research Center *Recruiting*
Port Charlotte, Florida, 33952
United States
Recruiting
Wolfson Medical Center *Recruiting*
Holon, , 58100
Israel
Recruiting
Heart Specialists *Terminated*
Nassau Bay, Texas, 77058
United States
Terminated
University Of North Carolina *Terminated*
Chapel Hill, North Carolina, 27599
United States
Terminated
University Alabama at Birmingham *Recruiting*
Birmingham, Alabama, 35294
United States
Recruiting
Alegent Health Heart and Vascular Institute *Recruiting*
Omaha, Nebraska, 68122
United States
Recruiting
Barzilai Medical Center *Recruiting*
Ashkelon, , 78306
Israel
Recruiting
University of Connecticut Health Center *Recruiting*
Farmington, Connecticut, 06030
United States
Recruiting
University of Maryland Hospital *Recruiting*
Baltimore, Maryland, 21201
United States
Recruiting
Jacksonville Heart Center PA-Baptist Office *Recruiting*
Jacksonville, Florida, 32207
United States
Recruiting
Nisus Research/Northern Michigan Hospital *Recruiting*
Petoskey, Michigan, 49770
United States
Recruiting
St. Luke's Episcopal Hospital/Texas Heart Institute *Terminated*
Houston, Texas, 77030
United States
Terminated
Overlake Hospital Medical Center *Terminated*
Bellevue, Washington, 98004
United States
Terminated
MIMA Century Research Associates *Recruiting*
Melbourne, Florida, 32901
United States
Recruiting
Via Christi Research Inc. dba PriVia *Recruiting*
Wichita, Kansas, 67214
United States
Recruiting
VA Greater Los Angeles Healthcare System *Recruiting*
Los Angeles, California, 90073
United States
Recruiting
Northwestern Memorial Hospital/Heart Failure Program *Recruiting*
Chicago, Illinois, 60611
United States
Recruiting
A.R.I. Clinical Trials, Inc. *Terminated*
Redondo Beach, California, 90277
United States
Terminated
Watson Clinic Center for Research *Recruiting*
Lakeland, Florida, 33805
United States
Recruiting
University Health Science Center/Cardio Section *Recruiting*
Oklahoma City, Oklahoma, 73104
United States
Recruiting
Level 2, Cardiology Department/Royal Melbourne Hospital *Recruiting*
Parkville, Victoria, 3050
Australia
Recruiting
Heart Hospital of New Mexico - NW Heart Institute *Recruiting*
Albuquerque, New Mexico, 87106
United States
Recruiting
Queen Elizabeth Hospital/Cardiology Department *Recruiting*
Woodville, South Australia, 5011
Australia
Recruiting
Gill Heart Institute/University of Kentucky *Terminated*
Lexington, Kentucky, 40536
United States
Terminated
Flinders Medical Centre - Cardiac Research Department *Recruiting*
Bedford Park, South Australia,
Australia
Recruiting
Heart Research Institute/Sir Charles Gairdner Hospital *Recruiting*
Nedlands, Western Australia, 6009
Australia
Recruiting
Christiana Care Health System *Terminated*
Newark, Delaware, 19718
United States
Terminated
Sentara Norfolk General Hospital *Terminated*
Norfolk, Virginia, 23507
United States
Terminated
Merced Heart Associates *Recruiting*
Merced, California, 95340
United States
Recruiting
Boston Medical Center *Recruiting*
Boston, Massachusetts, 02118
United States
Recruiting
Hillsboro Cardiology, PC *Terminated*
Hillsboro, Oregon, 97123
United States
Terminated
Buxmont Cardiology Associates *Recruiting*
Sellersville, Pennsylvania, 18960
United States
Recruiting
University of Ottawa Health Institute *Not yet recruiting*
Ottawa, Ontario, K1Y 4W7
Canada
Not yet recruiting
St. Vincent's Hospital - Cardiology Investigational Unit *Recruiting*
Fitzroy, Victoria,
Australia
Recruiting
Providence Hospital Heart Failure Clinic *Recruiting*
Mobile, Alabama, 36685
United States
Recruiting
Arizona Heart Institute *Recruiting*
Phoenix, Arizona, 85006
United States
Recruiting
Denver Health Medical Center *Recruiting*
Denver, Colorado, 80204
United States
Recruiting
Dartmouth-Hitchcock Medical Center *Terminated*
Lebanon, New Hampshire, 03756
United States
Terminated
Jefferson Heart Institute *Terminated*
Philadelphia, Pennsylvania, 19107
United States
Terminated
George Washington University *Recruiting*
Washington D.C., District of Columbia, 20037
United States
Recruiting
Jack D. Weiler Hospital/Albert Einstein Hospital *Recruiting*
Bronx, New York, 10461
United States
Recruiting
Heart & Vascular Institute of Florida *Recruiting*
St. Petersburg, Florida, 33701
United States
Recruiting
San Diego Cardiac Center *Recruiting*
San Diego, California, 92123
United States
Recruiting
Jackson Memorial Hospital *Recruiting*
Miami, Florida, 33102
United States
Recruiting
University Hospitals of Cleveland *Recruiting*
Cleveland, Ohio, 44106
United States
Recruiting
Clarian Health - Methodist Research Institute Inc. *Terminated*
Indianapolis, Indiana, 46202
United States
Terminated
University of Arkansas for Medical Sciences *Terminated*
Little Rock, Arkansas, 72205
United States
Terminated
Carilion Department of Clinical Research *Recruiting*
Roanoke, Virginia, 24011
United States
Recruiting
The Ford Research Institute PA/NW Florida Heart Group PA *Terminated*
Pensacola, Florida, 32514
United States
Terminated
The Lindner Center *Recruiting*
Cincinnati, Ohio, 45219
United States
Recruiting
Oracle Research-The Heart Center *Recruiting*
Huntsville, Alabama, 35801
United States
Recruiting
Dallas VA Medical Center *Terminated*
Dallas, Texas, 75216
United States
Terminated
Inland Cardiology Associates *Recruiting*
Spokane, Washington, 99204
United States
Recruiting
International Heart Institute Montana Foundation *Recruiting*
Missoula, Montana, 59802
United States
Recruiting
Baystate Medical Center *Recruiting*
Springfield, Massachusetts, 01199
United States
Recruiting
Medical Research Institute *Recruiting*
Slidell, Louisiana, 70458
United States
Recruiting
Liverpool Hospital - Cardiology Research *Recruiting*
Liverpool, New South Wales, 2116
Australia
Recruiting
Cleveland Clinic Foundation/Department of Cardiology *Recruiting*
Cleveland, Ohio, 44195
United States
Recruiting
Cardiology Group, P.C. *Recruiting*
Tullahoma, Tennessee, 37388
United States
Recruiting
Montefiore Medical Center/Cardiology Department *Terminated*
Bronx, New York, 10467
United States
Terminated
Rush-Presbyterian-St. Luke's Medical Center *Recruiting*
Chicago, Illinois, 60612
United States
Recruiting
VA San Diego Healthcare System *Recruiting*
San Diego, California, 92161
United States
Recruiting
Royal Brisbane Hospital - Cardiology Department *Recruiting*
HERSTON, Queensland, QLD 4029
Australia
Recruiting
Central Cardiology Medical Center *Recruiting*
Bakersfield, California, 93301
United States
Recruiting
Hospital of Saint Raphael *Recruiting*
New Haven, Connecticut, 06511
United States
Recruiting
UCSD Medical Center, University of California *Recruiting*
San Diego, California, 92103
United States
Recruiting
Jacksonville Heart Center,PA *Recruiting*
Jacksonville, Florida, 32250
United States
Recruiting
Providence Portland Medical Center/Heart Failure Clinic *Terminated*
Portland, Oregon, 97213
United States
Terminated
San Diego Cardiovascular Research *Terminated*
Encinitas, California, 92024
United States
Terminated
Hillel Yaffe Medical Center *Recruiting*
Hadera, , 38100
Israel
Recruiting
Sieff Medical Center *Recruiting*
Zefat, , 13100
Israel
Recruiting
Los Angeles County/USC Medical Center *Terminated*
Los Angeles, California, 90033
United States
Terminated
William Beaumont Hospital *Terminated*
Royal Oak, Michigan, 48073
United States
Terminated
OSU Medical Center-Center Wellness & Prevention *Recruiting*
Columbus, Ohio, 43210
United States
Recruiting
Southwest Washington Medical Center *Recruiting*
Vancouver, Washington, 98664
United States
Recruiting
Oregon Health & Science University *Terminated*
Portland, Oregon, 97201
United States
Terminated
DUCCS Research of South Boston *Terminated*
South Boston, Virginia, 24592
United States
Terminated
Houston VA Medical Center *Recruiting*
Houston, Texas, 77030
United States
Recruiting
Sacramento Heart and Vascular Research Center *Recruiting*
Sacramento, California, 95825
United States
Recruiting
University of Florida *Recruiting*
Gainesville, Florida, 32610
United States
Recruiting
Prince of Wales Hospital *Recruiting*
Randwick, New South Wales,
Australia
Recruiting
Rockyview Hospital, Heart Health Institute *Not yet recruiting*
Calgary, Alberta, T2V 1P9
Canada
Not yet recruiting
Central Arkansas Veterans Healthcare System *Recruiting*
Little Rock, Arkansas, 72205
United States
Recruiting
Elgin Cardiology Associates *Terminated*
Elgin, Illinois, 60120
United States
Terminated
Columbia-Presbyterian Medical Center *Recruiting*
New York City, New York, 10032
United States
Recruiting
Henry Ford Health System *Terminated*
Detroit, Michigan, 48202
United States
Terminated
University of Texas Health Sciences *Recruiting*
San Antonio, Texas, 78229
United States
Recruiting
Royal North Shore Hospital - Cardiology Department *Recruiting*
St. Leonards, New South Wales,
Australia
Recruiting
Sarver Heart Center - University of Arizona Health Science *Terminated*
Tucson, Arizona, 85724
United States
Terminated
Loma Linda University Medical Center *Terminated*
Loma Linda, California, 92354
United States
Terminated
Augusta Cardiology Clinic, P.C. *Recruiting*
Augusta, Georgia, 30901
United States
Recruiting
The Johns Hopkins Hospital *Recruiting*
Baltimore, Maryland, 21287
United States
Recruiting
New Orleans Clinical Trial Management, Inc. *Recruiting*
Covington, Louisiana, 70433
United States
Recruiting
The Milton S. Hershey Medical Center *Recruiting*
Hershey, Pennsylvania, 17033
United States
Recruiting
University of Pittsburgh *Terminated*
Pittsburgh, Pennsylvania, 15213
United States
Terminated
UTHCT/Center for Clinical Research *Terminated*
Tyler, Texas, 75708
United States
Terminated
Hahnemann University Hospital/HF and Transplant Center *Recruiting*
Philadelphia, Pennsylvania, 19102
United States
Recruiting
Florida Cardiovascular Institute *Recruiting*
Tampa, Florida, 33609
United States
Recruiting
Baptist Clinical Research Center *Recruiting*
Memphis, Tennessee, 38120
United States
Recruiting
Concord Hospital - Heart Failure Clinic/Department of Cardiology *Recruiting*
Concord, New South Wales, NSW 2139
Australia
Recruiting
VA Medical Center - Cardiology Department *Recruiting*
Minneapolis, Minnesota, 55417
United States
Recruiting
Cardiology, P.C. Research *Recruiting*
Birmingham, Alabama, 35211
United States
Recruiting
Royal Hobart Hospital *Recruiting*
Hobart, Tasmania, 7000
Australia
Recruiting
Tulane University Health Sciences Center *Terminated*
New Orleans, Louisiana, 70112
United States
Terminated
Neureka Research, Willet Green Niller Centre *Not yet recruiting*
Sudbury, Ontario, P3E 6B4
Canada
Not yet recruiting
University of Washington *Recruiting*
Seattle, Washington, 98195
United States
Recruiting
Canberra Hospital/Cardiology Department *Recruiting*
Garran, Australian Capital Territory, 2605
Australia
Recruiting
Louisiana Heart Center *Recruiting*
Chalmette, Louisiana, 70043
United States
Recruiting
Heart Group *Recruiting*
Lancaster, Pennsylvania, 17603
United States
Recruiting
Midwest Heart Research Foundation *Terminated*
Lombard, Illinois, 60148
United States
Terminated
Hackensack University Medical Center *Terminated*
Hackensack, New Jersey, 07601
United States
Terminated
Kaplan Medical Center *Recruiting*
Rehovot, , 76100
Israel
Recruiting
Cedars-Sinai Medical Center *Recruiting*
Los Angeles, California, 90048
United States
Recruiting
Beloit Clinic, SC *Terminated*
Beloit, Wisconsin, 53511
United States
Terminated
Royal Prince Alfred Hospital/Department of Cardiology *Recruiting*
Camperdown, New South Wales, 2050
Australia
Recruiting
University of Alberta Hospitals *Not yet recruiting*
Edmonton, Alberta, T6G 2R7
Canada
Not yet recruiting
Assaf Harofe Medical Center *Recruiting*
Zrifin, , 70300
Israel
Recruiting
Yale University School of Medicine/Heart Failure Center *Terminated*
New Haven, Connecticut, 06510
United States
Terminated
Heart Institute, Hadassah MC *Recruiting*
Jerusalem, , 91120
Israel
Recruiting
Rhode Island Hospital/University Cardiology *Recruiting*
Providence, Rhode Island, 02905
United States
Recruiting
Cardiopulmonary Research Science & Technology Institute *Recruiting*
Dallas, Texas, 75230
United States
Recruiting
Wayne State University *Terminated*
Detroit, Michigan, 48201
United States
Terminated
Cardiovascular Research Institute of Dallas *Recruiting*
Dallas, Texas, 75231
United States
Recruiting
Iowa Heart Center *Terminated*
Des Moines, Iowa, 50314
United States
Terminated
Heart Care Midwest *Recruiting*
Peoria, Illinois, 61603
United States
Recruiting
St. Luke's Medical Center *Recruiting*
Milwaukee, Wisconsin, 53215
United States
Recruiting
University Hospitals Clinic *Terminated*
Columbus, Missouri, 65212
United States
Terminated
Cardiology Associates of West Reading *Terminated*
West Reading, Pennsylvania, 19611
United States
Terminated
Karinia House/Geelong Hospital *Recruiting*
Geelong, Victoria, 3220
Australia
Recruiting
Michigan Heart P.C. *Terminated*
Ypsilanti, Michigan, 48197
United States
Terminated
Universtiy of PA Health System *Recruiting*
Philadelphia, Pennsylvania, 19104
United States
Recruiting
University of Michigan Medical Center, CACR *Terminated*
Ann Arbor, Michigan, 48109
United States
Terminated
Baylor College of Medicine *Recruiting*
Houston, Texas, 77030
United States
Recruiting
Oklahoma Foundation-Cardiovascular *Recruiting*
Oklahoma City, Oklahoma, 73104
United States
Recruiting
Memorial Health University Medical Center Research Center *Terminated*
Savannah, Georgia, 31405
United States
Terminated
John Hopkins Bayview Medical Center *Terminated*
Baltimore, Maryland, 21224
United States
Terminated
Washington Hospital Center - Cardiac Surgery Department *Recruiting*
Washington D.C., District of Columbia, 20010
United States
Recruiting
St. Paul Clinic *Recruiting*
St. Paul, Minnesota, 55102
United States
Recruiting
The Creighton Cardiac Center *Recruiting*
Omaha, Nebraska, 68131
United States
Recruiting
University of Cincinnati Medical Center *Recruiting*
Cincinnati, Ohio, 45219
United States
Recruiting
University Hospital, Iowa City *Recruiting*
Iowa City, Iowa, 52242
United States
Recruiting
The Toledo Clinic & Outpatient Surgery *Terminated*
Toledo, Ohio, 43623
United States
Terminated
University of Saskatchewan *Not yet recruiting*
Saskatoon, Saskatchewan, S7N 3R2
Canada
Not yet recruiting
Geisinger Health System *Terminated*
Danville, Pennsylvania, 17822
United States
Terminated
Center Hospital University of Sherbrooke *Not yet recruiting*
Sherbrooke, Quebec, J1H 5N4
Canada
Not yet recruiting
Box Hill Hospital - Coronary Care Unit *Recruiting*
Box Hill, Victoria,
Australia
Recruiting
University of Calgary *Not yet recruiting*
Calgary, Alberta, T2N 4N1
Canada
Not yet recruiting
Miami Research & Education Foundation *Terminated*
Miami, Florida, 33156
United States
Terminated
Apex Cardiology Consultants, Inc. *Recruiting*
Inglewood, California, 90301
United States
Recruiting
Cardiac Centers of Louisiana, LLC *Recruiting*
Shreveport, Louisiana, 71135
United States
Recruiting
Saint Louis University Hospital *Recruiting*
St. Louis, Missouri, 63110
United States
Recruiting
Cardiovascular Associates/Office of Clinical Research *Terminated*
Birmingham, Alabama, 35209
United States
Terminated
University of Minnesota *Terminated*
Minneapolis, Minnesota, 55455
United States
Terminated
St. George Hospital/Cardiology Department *Recruiting*
Sydney, New South Wales,
Australia
Recruiting
Beth Israel Medical Center NY/Phillips Ambulatory Care Center *Terminated*
New York City, New York, 10003
United States
Terminated
Gosford Hospital *Recruiting*
Gosford, New South Wales,
Australia
Recruiting
EMMS Nazareth Hospital *Recruiting*
Nazareth, , 16100
Israel
Recruiting
Toledo Clinic & Outpatient Surgery/Department of Cardiology *Terminated*
Toledo, Ohio, 43623
United States
Terminated
Additional Information:
Study ID Numbers: 3001069;
Study Start Date:
Record last reviewed: May 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00048425
Other Heart Failure, Congestive Studies:
1. Effect of Behavioral Management on Quality of Life in Heart Failure
2. The DIAMOND Study: Distensibility Improvement And Remodeling in Diastolic Heart Failure
3. Exercise Effect on Aerobic Capacity and Quality of Life in Heart Failure
4. Telephone Intervention in Heart Failure Patients
5. The Role of Angiotensin Type I Receptor in the Regulation of Human Coronary Vascular Function
Related Studies:
Other Heart Failure, Congestive Clinical Trials
Other Indiana Clinical Trials
Other Indianapolis Clinical Trials
Evaluation of Intravenous Levosimendan Efficacy in the Short Term Treatment of Decompensated Chronic Heart Failure.
|
|
|
|
|
|
|
|
