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Home > "E" Clinical Trials Conditions > Erlotinib in Treating Patients with Advanced Non-Small Cell Lung Cancer Erlotinib in Treating Patients with Advanced Non-Small Cell Lung Cancer
Erlotinib in Treating Patients with Advanced Non-Small Cell Lung Cancer
For Condition: Carcinoma, Non-Small-Cell Lung
Status: Recruiting
Sponsor(s): OSI Pharmaceuticals ,
Synopsis: The purpose of this study is to determine if erlotinib will improve disease at doses that produce its characteristic rash in patients with advanced Non-Small Cell Lung Cancer.
Details: Only patients with 0 to 1 performance status on the ECOG scale are eligible.
Eligibility:
Study Type: Interventional, Treatment, Non-Randomized, Open Label, Uncontrolled, Single Group Assignment, Safety/Efficacy Study
Minimum Age/Maximum Age: 18 Years/
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Confirmed diagnosis of Stage IIIB or IV non-small cell lung cancer (histological or cytological). - Received prior chemotherapy treatment for advanced, metastatic non-small cell lung cancer. - Measurable disease per RECIST criteria. - Adequate bone marrow, hepatic, and renal function. Exclusion Criteria: - Breast cancer or skin cancer at any time in the past or any other cancer in the past 5 years. - Brain metastases that are unstable, require steroids, are life-threatening, or required radiation in the last 28 days. - Known hypersensitivity to minocycline. - History of serious cardiac disease that is not controlled. - Serious eye conditions. - Prior treatment with inhibitors of EGFR of any kind.
Total Enrollment: 50
Location and Contact Information:
CTRC Institute for Drug Development *Recruiting*
San Antonio, Texas, 78229
United States
Recruiting OSIP Information 800-572-1932
Additional Information:
Study ID Numbers: OSI-774-202; Dose to Rash
Study Start Date: August 2003
Record last reviewed: November 2003
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00072631
Other Carcinoma, Non-Small-Cell Lung Studies:
1. A Phase 2 Trial of Antisense Nucleotide to PKC-alpha (LY900003, ISIS 3521) Plus Gemcitabine and Carboplatin in Patients with Advanced, Previously Untreated Non-Small Cell Lung Cancer.
2. Trial of Avastin and Tarceva for Locally Advanced or Metastatic Non-Squamous Non-Small-Cell Lung Cancer in Previously Treated Patients
3. Iressa Expanded Access Program (EAP)
4. A Phase 3 Randomized Study of Lonafarnib in Combination With Paclitaxel and Carboplatin vs. Placebo in Combination with Paclitaxel and Carboplatin in Patients With Non-Small Cell Lung Cancer
5. Mistletoe Extract and Gemcitabine for the Treatment of Solid Tumor Cancers
Related Studies:
Other Carcinoma, Non-Small-Cell Lung Clinical Trials
Other Texas Clinical Trials
Other San Antonio Clinical Trials
Erlotinib in Treating Patients with Advanced Non-Small Cell Lung Cancer
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