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Electroconvulsive Therapy (ECT) Versus Drug Therapy for the Treatment of Depression Clinical Trials Information presented on Clinical Trials Search isn't designed to be a substitute for certified healthcare advice, travels to or professional assistance using a genuine medical doctor. We are not physicians. Always confer with your dr. about Electroconvulsive Therapy (ECT) Versus Drug Therapy for the Treatment of Depression conditions. Clinical Trials Search.org is a site devoted to listing clinical research studies in human subjects. Electroconvulsive Therapy (ECT) Versus Drug Therapy for the Treatment of Depression Clinical research trials and Electroconvulsive Therapy (ECT) Versus Drug Therapy for the Treatment of Depression medical trials happen in hundreds of places across the United States. A clinical trial or clinical study is a research project with human volunteer subjects. Clinical drug trials and pharmaceutical clinical trials usually measure the effectualness of new drugs. The intention of the studies / undertakings is to solve certain human healthcare questions. Clinical trials are a popular manner for mDs, government agencies, and private sector companies to locate treatments for all forms of circumstances, such as Electroconvulsive Therapy (ECT) Versus Drug Therapy for the Treatment of Depression. Electroconvulsive Therapy (ECT) Versus Drug Therapy for the Treatment of Depression Clinical Trials and other clinical trials allow for volunteers to undergo medical treatment choices before they are available to the general public. Some times the human subjects get treatment for free of charge, and sometimes they are paid for their time. Occasionally there is a cost for a Electroconvulsive Therapy (ECT) Versus Drug Therapy for the Treatment of Depression clinical trial. Participants frequently get the best healthcare available for their Electroconvulsive Therapy (ECT) Versus Drug Therapy for the Treatment of Depression condition. Risks are a reality, nonetheless, and can include extra or frequent physician trips, medical risks (possibly life-jeopardising), and/or the treatment being ineffective. Trials are federally governed with exacting guidelines to protect clinical trials subjects.
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Home > "E" Clinical Trials Conditions > Electroconvulsive Therapy (ECT) Versus Drug Therapy for the Treatment of Depression  Electroconvulsive Therapy (ECT) Versus Drug Therapy for the Treatment of Depression
Electroconvulsive Therapy (ECT) Versus Drug Therapy for the Treatment of Depression
For Condition: Depression
Status: No longer recruiting
Sponsor(s): National Institute of Mental Health (NIMH) ,
Synopsis: The purpose of this study is to compare continuation electroconvulsive therapy (C-ECT) to the drug combination of nortriptyline plus lithium in preventing a return of symptoms following initial ECT treatment in individuals with major depression.
Details: ECT is a highly effective treatment for major depressive disorder (MDD). However, depression relapse after acute-phase ECT remains a major public health problem. C-ECT may prevent a relapse of depressive symptoms, but its efficacy and safety have not been rigorously tested. This study will define the role of C-ECT in relapse prevention in people with MDD. Participants with MDD who experience a remission of depressive symptoms after an acute course of bilateral ECT will be randomly assigned to receive either nortriptyline plus lithium or C-ECT. Cognitive performance, global functioning, perceived health status, and susceptibility to side effects will be assessed. Neuropsychological tests, depression scales, and interviews will be used to assess participants.
Eligibility:
Study Type: Interventional, Treatment, Randomized, Active Control, Parallel Assignment, Efficacy Study
Minimum Age/Maximum Age: 18 Years/85 Years
Genders: Both
Protocol Entry Criteria: Inclusion Criteria: - Diagnosis of unipolar major depression - Referred for electroconvulsive therapy (ECT)
Total Enrollment: 55
Location and Contact Information:
UMDNJ
Newark, New Jersey, 07103
United States
Mayo Foundation
Rochester, Minnesota, 55905
United States
University of Texas Southwestern Medical Center
Dallas, Texas, 75235
United States
Northshore/Long Island Jewish Hilldide Hospital
Glen Oaks, New York, 11004
United States
Additional Information:
Study ID Numbers: 55495-06;
Study Start Date:
Record last reviewed: March 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00069394
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2. Antidepressant Treatment of AIDS Related Depression.
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5. The Effects of Hormone Withdrawal on Mood Symptoms in Women with Perimenopausal Depression
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Electroconvulsive Therapy (ECT) Versus Drug Therapy for the Treatment of Depression
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