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Efficacy of Osteopathic Manipulation in Chronic Obstructive Pulmonary Disease



Efficacy of Osteopathic Manipulation in Chronic Obstructive Pulmonary Disease

For Condition: Emphysema
Status: No longer recruiting
Sponsor(s): National Center for Complementary and Alternative Medicine (NCCAM) ,
Synopsis: The purpose of this study is to determine if osteopathic manipulative treatment (OMT) is effective for persons with emphysema as a component of their chronic obstructive pulmonary disease.
Details: OMT sessions are designed to improve chest wall compliance and diaphragmatic function which produce an immediate positive change in pulmonary function parameters and chest wall mobility. This research project will be a significant step in expanding the understanding of the role of OMT in the treatment of chronic lung disease. It is expected to yield evidence that OMT is an important adjunctive modality that improves pulmonary function, increases exercise tolerance, relieves dyspnea, and improves quality of life in those with COPD, and that would have widespread clinical application plus significant economic benefits. Participants in this study will be randomly assigned to receive either OMT or sham treatments once a week for 13 weeks. Outcome measures will be obtained at baseline; immediately following the first treatment; at 4, 8, and 12 weeks after initiation of treatment; and 4 weeks after termination of the treatment. Outcome variables include pulmonary function tests; quality-of-life questionnaires (including emotional functioning, fatigue, and dyspnea); and measurements of exercise tolerance and chest wall mobility.
Eligibility:
Study Type:
  Interventional, Treatment, Randomized, Placebo Control
Minimum Age/Maximum Age: /
Genders: 
Protocol Entry Criteria: 
Total Enrollment: 

Location and Contact Information:

Kirksville College of Osteopathic Medicine
Kirksville,  Missouri,  63501
United States
 


Additional Information:
Study ID Numbers:
  1 R21 AT00207-01A1; 
Study Start Date: April 2001
Record last reviewed: March 2004
Additional information available at: clinicaltrials.gov
Clinicaltrials.gov Reference link: NCT00034112

Other Emphysema Studies:
1. Determine the Safety and Efficacy of (R,R)-Formoterol in the Treatment of Subjects with COPD

2. Cost-Effectiveness of Lung Volume Reduction Surgery

3. Efficacy of Osteopathic Manipulation in Chronic Obstructive Pulmonary Disease

4. National Emphysema Treatment Trial (NETT)

5. Medication Adherence in COPD--A Self-Regulation Study

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Efficacy of Osteopathic Manipulation in Chronic Obstructive Pulmonary Disease

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